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RNA Control and Regulation: (Cold Spring Harbor Symposia on Quantitative Biology LXXXIV) [Pehme köide]

(Cold Spring Harbor Laboratory), (Cold Spring Harbor Laboratory), (Cold Spring Harbor Laboratory)
  • Formaat: Paperback / softback, 310 pages
  • Sari: Symposium Proceedings
  • Ilmumisaeg: 31-Aug-2020
  • Kirjastus: Cold Spring Harbor Laboratory Press,U.S.
  • ISBN-10: 162182392X
  • ISBN-13: 9781621823926
Teised raamatud teemal:
  • Formaat: Paperback / softback, 310 pages
  • Sari: Symposium Proceedings
  • Ilmumisaeg: 31-Aug-2020
  • Kirjastus: Cold Spring Harbor Laboratory Press,U.S.
  • ISBN-10: 162182392X
  • ISBN-13: 9781621823926
Teised raamatud teemal:
Previous Cold Spring Harbor Symposia have addressed many different aspects of RNA biology such as Mechanisms of Transcription (1998), The Ribosome (2001), Epigenetics (2004) and Regulatory RNAs (2006). The 84th Cold Spring Harbor Symposium focused on RNA Control & Regulation and provided a current synthesis of the enormous progress in our understanding of RNA's influence on cells and organisms and how, when aberrant, its effects may contribute to the progression of disease. It is rare to find such a wide-ranging perspective on this topic in one volume and this collection of papers will be valuable to investigators in many fields. The topics covered at the meeting included: RNA-Based Structures; RNA Modifications; Nuclear Localization of RNA; Quality Control & Editing; RNA & Gene Regulation; Cotranscriptional Splicing; Intron/Exon Boundaries; Alternative Polyadenylation; Transposon Control; Small Noncoding RNAs; Long Noncoding RNAs; RNA & Development; Membrane-Less Organelles; Phase Separation; RNA-Based Diseases; and Novel RNA Functions. Numerous speakers participated in interviews during the course of the Symposium week and this volume includes transcripts of those discussions and the Dorcas Cummings lecture, for the general public, which was given by Dr. Jennifer Doudna.
Symposium Participants vii
Foreword xix
Global Analyses and Structures
Zipcode Binding Protein 1 (ZBP1; IGF2BP1): A Model for Sequence-Specific RNA Regulation
1(10)
Jeetayu Biswas
Leti Nunez
Sulagna Das
Young J. Yoon
Carolina Eliscovich
Robert H. Singer
Pre-mRNA Splicing in the Nuclear Landscape
11(10)
Tucker J. Carrocci
Karla M. Neugebauer
Recognition of Poly(A) RNA through Its Intrinsic Helical Structure Terence
21(10)
T.L. Tang
Lori A. Passmore
Subcellular Spatial Transcriptomes: Emerging Frontier for Understanding Gene Regulation
31(16)
Furqan M. Fazal
Howard Y. Chang
Gene Regulation
Transcriptional Coactivator PGC-1α Binding to Newly Synthesized RNA via CBP80: A Nexus for Co- and Posttranscriptional Gene Regulation
47(8)
Xavier Rambout
Hana Cho
Lynne E. Maquat
Mechanistic Dissection of RNA-Binding Proteins in Regulated Gene Expression at Chromatin Levels
55(12)
Jia-Yu Chen
Do-Hwan Lim
Xiang-Dong Fu
Linking RNA Processing and Function
67(16)
Run-Wen Yao
Chu-Xiao Liu
Ling-Ling Chen
Attenuation of Eukaryotic Protein-Coding Gene Expression via Premature Transcription
83(12)
Termination Deirdre C. Tatomer
Jeremy E. Wilusz
Regulation of RNA Functions
3' UTRs Regulate Protein Functions by Providing a Nurturing Niche during Protein Synthesis
95(10)
Christine Mayr
The THO Complex as a Paradigm for the Prevention of Cotranscriptional R-Loops Rosa Luna
105(10)
Ana G. Rondon
Carmen Perez-Calero
Irene Salas-Armenteros
Andres Aguilera
U1 snRNP Telescripting Roles in Transcription and Its Mechanism
115(8)
Chao Di
Byung Ran So
Zhiqiang Cai
Chie Arai
Jingqi Duan
Gideon Dreyfuss
Functional and Mechanistic Interplay of Host and Viral Alternative Splicing Regulation during Influenza Infection
123(10)
Matthew G. Thompson
Kristen W. Lynch
Chromatin and RNA
Small RNA Function in Plants: From Chromatin to the Next Generation Jean-Sebastian Parent
133(8)
Filipe Borges
Atsushi Shimada
Robert A. Martienssen
A Nuclear RNA Degradation Pathway Helps Silence Polycomb/H3K27me3-Marked Loci in Caenorhabditis elegans
141(14)
Anna Mattout
Dimos Gaidatzis
Veronique Kalck
Susan M. Gasser
To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome
155(10)
Mahesh Lingaraju
Jan M. Schuller
Sebastian Falk
Piotr Gerlach
Fabien Bonneau
Jerome Basquin
Christian Benda
Elena Conti
Long Noncoding RNAs in Development and Regeneration of the Neural Lineage
165(14)
Hadas Hezroni
Rotem Ben Tov Perry
Igor Ulitsky
Small RNAs and Defense Systems
How Complementary Targets Expose the microRNA 3' End for Tailing and Trimming during Target-Directed microRNA Degradation
179(6)
Paulina Pawlica
Jessica Sheu-Gruttadauria
Ian J. MacRae
Joan A. Steitz
Dicer's Helicase Domain: A Meeting Place for Regulatory Proteins
185(10)
Sarah R. Hansen
Adedeji M. Aderounmu
Helen M. Donelick
Brenda L. Bass
Reconstitution of siRNA Biogenesis In Vitro: Novel Reaction Mechanisms and RNA Channeling in the RNA-Directed DNA Methylation Pathway
195(8)
Jasleen Singh
Craig S. Pikaard
Membraneless Bodies and Phase Separation
RNP Granule Formation: Lessons from P-Bodies and Stress Granules
203(14)
Giulia Ada Corbet
Roy Parker
Biophysical Properties of HP1 -Mediated Heterochromatin
217(10)
Serena Sanulli
John D. Gross
Geeta J. Narlikar
Architectural RNAs for Membraneless Nuclear Body Formation
227(12)
Tomohiro Yamazaki
Shinichi Nakagawa
Tetsuro Hirose
Summary
Myriad RNAs and RNA-Binding Proteins Control Cell Functions, Explain Diseases, and Guide New Therapies
239(4)
Byung Ran So
Gideon Dreyfuss
Dorcas Cuminings Lecture
243(8)
Dorcas Cummings Lecture
245(6)
Jennifer Doudna
Conversations at the Symposium
251(54)
Karen Adelman
253(3)
Andres Aguilera
256(3)
David Bartel
259(3)
Ling-Ling Chen
262(2)
Caroline Dean
264(2)
Susan Gasser
266(2)
Sarnie Jaffrey
268(3)
Leemor Joshua-Tor
271(3)
Alberto Kornblihtt
274(2)
Adrian Krainer
276(3)
Lynne Maquat
279(3)
Karla Neugebauer
282(3)
Nicholas Proudfoot
285(3)
Oliver Rando
288(3)
Phillip Sharp
291(3)
Maria-Elena Torres-Padilla
294(2)
Igor Ulitsky
296(3)
Jeremy Wilusz
299(3)
Feng Zhang
302(3)
Author Index 305(2)
Subject Index 307