These receptors are not similar either to the sound of a bell or to the fee to cross a bridge, but to a specific receptor discovered in the Drosophila embryo in 1996, and named toll. Researchers in neurobiology, immunology, and related specialties provide a theoretical and practical foundation for scientists at any level who are interested in studying their role in signal transduction at the cellular level. Among the topics are the intra-cellular trafficking of toll-like receptors, using receptor chimeras to dissect mechanisms of receptor localization and signaling, and the influence of injury on the receptors. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
