The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to chemical warfare agents and toxic industrial chemicals because it decreases serious skin damage to the patient and, potentially, their doctor.
This multi-authored international text pulls together a century of decontamination research and helps the reader expedite solutions that will decrease morbidity and mortality. Complete with dozens of hiqh quality photographs and illustrations, Skin Decontamination aids industrial hygiene, dermatology, occupational physicians and thoseinvolved in the public health arena.
Chapter
1. Isolated Human and Animal Stratum Corneum As a Partial Model
for the 15 Steps of Percutaneous Absorption: Emphasizing Decontamination,
Part I.- Chapter
2. Isolated Human And Animal Stratum Corneum As A Partial
Model For The 15 Steps Of Percutaneous Absorption: Emphasizing
Decontamination Part II.- Chapter
3. Recent Knowledge: Human/Animal Skin
Decontamination.- Chapter
4. The Decontamination of Chemically Contaminated
Remains.- Chapter
5. Effectiveness of Chemical, Biological, Radiological, and
Nuclear (CBRN) Skin Decontaminants: Towards Tests Standardization.- Chapter
6. Effects of Soap-Water Wash on Human Epidermal Penetration.- Chapter
7.
Fuller's Earth: Old and Faithful Skin Decontaminant Against Toxic
Agents.- Chapter
8. Comparison of Four Different Fullers Earth Formulations
in Skin Decontamination.- Chapter
9. The Mass Decontamination Paradigm:
Response Relating to Gas Phase Exposures and Skin
Decontamination.- Chapter10. Binding Affinity and Decontamination of Dermal
Decontamination Gel (DDGel) to Model Chemical Warfare Agent (CWA)
Simulants.- Chapter
11. Dermostyx (IB1): High-efficacy and Safe Topical Skin
Protectant Against Percutaneous Toxic Agents.- Chapter
12. Understanding the
Impact of Responder Management Strategies on Public Experiences and Behaviour
During Mass Decontamination.
Hanjiang Zhu, PhD
University of California San Francisco, Dermatology
Department of Dermatology
2340 Sutter Street N461
San Francisco, CA 94143/0989
USA
Tel: 408-829-3797
Fax: 415-753-5304
sunnie.zhu@foxmail.com
Howard I. Maibach, MD
Professor, Dermatologist
University of California San Francisco
Department of Dermatology
2340 Sutter Street N461
San Francisco, CA 94143/0989
USA
Tel: (415)673-9693
Fax: (415) 673-3533
