Muutke küpsiste eelistusi

Small Molecule Microarrays: Methods and Protocols 2010 [Kõva köide]

Edited by , Edited by
  • Formaat: Hardback, 228 pages, kõrgus x laius: 254x178 mm, kaal: 711 g, XI, 228 p., 1 Hardback
  • Sari: Methods in Molecular Biology 669
  • Ilmumisaeg: 21-Sep-2010
  • Kirjastus: Humana Press Inc.
  • ISBN-10: 1607618443
  • ISBN-13: 9781607618447
Teised raamatud teemal:
  • Kõva köide
  • Hind: 141,35 €*
  • * hind on lõplik, st. muud allahindlused enam ei rakendu
  • Tavahind: 166,29 €
  • Säästad 15%
  • Raamatu kohalejõudmiseks kirjastusest kulub orienteeruvalt 2-4 nädalat
  • Kogus:
  • Lisa ostukorvi
  • Tasuta tarne
  • Tellimisaeg 2-4 nädalat
  • Lisa soovinimekirja
  • Formaat: Hardback, 228 pages, kõrgus x laius: 254x178 mm, kaal: 711 g, XI, 228 p., 1 Hardback
  • Sari: Methods in Molecular Biology 669
  • Ilmumisaeg: 21-Sep-2010
  • Kirjastus: Humana Press Inc.
  • ISBN-10: 1607618443
  • ISBN-13: 9781607618447
Teised raamatud teemal:
Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols showcases a collection of contributions guiding researchers toward ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. Organized by the categories of small molecules presented on the microarrays, this detailed volume describes in-depth techniques for chemical libraries, peptide libraries, and carbohydrate microarrays. Written in the highly successful Methods in Molecular BiologyT series, chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, vital tips on troubleshooting this often difficult technology, and advice on avoiding known pitfalls.Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous depictions of key hands-on experience and seeks to inspire a future generation of microarray practitioners to take this significant technology forward.

This title examines ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. It details techniques for chemical libraries, peptide libraries and carbohydrate microarrays.
Preface v
Contributors ix
1 The Expanding World of Small Molecule Microarrays
1(16)
Mahesh Uttamchandani
Shao Q. Yao
2 Construction of Photo-Cross-Linked Microarrays of Small Molecules
17(6)
Naoki Kanoh
3 Small Molecule Microarray: Functional-Group Specific Immobilization of Small Molecules
23(20)
Hyang Yeon Lee
Seung Bum Park
4 Detecting Protein-Small Molecule Interactions Using Fluorous Small Molecule Microarrays
43(14)
Arturo J. Vegas
Angela N. Koehler
5 A Method for Small Molecule Microarray-Based Screening for the Rapid Discovery of Affinity-Based Probes
57(12)
Haibin Shi
Mahesh Uttamchandani
Shao Q. Yao
6 Nanodroplet Chemical Microarrays and Label-Free Assays
69(10)
Dhaval Gosalia
Scott L. Diamond
7 Nanodroplet Microarrays for High-Throughput Enzyme Screening
79(16)
Kang L.D. Aw
Shao Q. Yao
Mahesh Uttamchandani
8 The Application of the Chemical Array for Biological Study
95(14)
Isao Miyazaki
Siro Simizu
Hiroyuki Osada
9 Peptide Arrays with a Chip
109(16)
Alexander Nesterove
Edgar Dorsam
Yun-Chien Cheng
Christopher Schirwitz
Frieder Markle
Felix Loffler
Kai Konig
Volker Stadler
Ralf Bischoff
Frank Breitling
10 In situ Chemical Modification of Peptide Microarrays: Characterization by Desorption/Ionization on Silicon Nanowires
125(10)
Gaelle Piret
Herve Drobecq
Rabah Boukherroub
Oleg Melnyk
11 In situ Chemical Modification of Peptide Microarrays: Application to the Study of the Antibody Responses to Methylated Antigens
135(12)
Remi Desmet
Eric Diesis
Herve Drobecq
Carine Rouanet
Karim Chemlal
Anne-Sophie Debrie
Jean-Michel Hougardy
Francoise Mascart
Camille Locht
Oleg Melnyk
12 Peptide Microarrays on Coated Silicon Slides for Highly Sensitive Antibody Detection
147(14)
Marina Cretich
Francesco Damin
Renato Longhi
Cecilia Gotti
Clelia Galati
Lucio Renna
Marcella Chiari
13 Antibody Signatures Defined by High-Content Peptide Microarray Analysis
161(12)
Antonia Masch
Johannes Zerweck
Ulf Reimer
Holger Wenschuh
Mike Schutkowski
14 High Density Peptide Microarrays for Proteome-Wide Fingerprinting of Kinase Activities in Cell Lysates
173(10)
Alexandra Thiele
Matthias Weiwad
Johannes Zerweck
Gunter Fischer
Mike Schutkowski
15 A Peptide Microarray for Detecting Protein Kinase Activity in Cell Lysates
183(12)
Xiaoming Han
Yoshiki Katayama
16 Chemical Microarrays Constructed by Selective Attachment of Hydrazide-Conjugated Substances to Epoxide Surfaces and Their Applications
195(14)
Sungjin Park
Myung-Ryul Lee
Injae Shin
17 A Microarray-Based Method to Perform Nucleic Acid Selections
209(16)
Olga Aminova
Matthew D. Disney
Index 225