Smart Biosensor Technology [Kõva köide]

A smart biosensor, as Knopf (mechanical and materials engineering, U. of Ontario, Canada) and Bassi (chemical and biochemical engineering, U. of Ontario) define it, is "a compact analytical device that combines a biological, or biologically derived, sensing element with an electrical, optical, or chemical transducer." Stressing that it is the synergistic functional integration of component parts that makes a biosensor "smart," they present 23 chapters that together provide a multidisciplinary perspective on the field. Opening chapters discuss the intelligent properties of biological macromolecules, optical methods of single molecule detection, nanoscale optical biosensors and biochips for cellular diagnostics, conducting polymer nanowire-based biomolecular field-effect transistor, machine learning and smart biosensor functions, and neuronal network biosensors. Seven chapters then address issues of material design and selection, followed by a section on bioelectronics. The volume concludes with six chapters on applications in detection and monitoring, including optical biosensors in foodborne pathogen detection, multiarray biosensors for toxicity monitoring and bacterial pathogens, approaches to allergy detection using aptasensors, biosensors for virus detection, and detection of influenza. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

Synergy is the key to creating more intelligent biosensors. Engineers develop smaller, more integrated technologies; biologists and chemists develop increasingly selective and sensitive sensor elements; material scientists develop ways to bring it all together. However, most books focus only on the chemistry aspects of biosensor technologies. With a multidisciplinary perspective, Smart Biosensor Technology examines the design, applications, and future directions of this rapidly evolving field.

This book collects contributions from leading specialists in a variety of scientific and engineering disciplines involved in different aspects of biosensor design and technology. Five broad sections provide a systematic structure that builds progressively from key concepts to emerging technologies and future directions. Following an introduction to the fundamental characteristics and functions of the underlying technologies, two sections explore the role materials play in developing smart biosensors. Next, the editors devote an entire section to bioelectronics with a focus on a biophotonic material called bacteriorhodopsin and its application to photoelectric biosensing, chemical sensing, and color imaging. They also present design and fabrication of new bioelectronic sensing arrays on flexible substrates. The final section explores a variety of smart biosensor applications in detecting food pathogens, monitoring toxicity, and detecting allergens and viruses.

Building a solid background in the underlying technologies and demonstrating how to apply this knowledge to solve real problems, Smart Biosensor Technology is a comprehensive, interdisciplinary guide to extending the capabilities of biosensors for a broad range of fields.