The way in which a cell maintains its total calcium content is a central issue in physiology. While the calcium level is to some extent controlled by intracellular mechanisms, it ultimately depends upon the rate of transportation of calcium ions into and out of the cell across the plasma membrane. The sodium-calcium exchange system provides a unique means of controlling calcium fluxes, thus playing a key role in many cellular functions, from muscle contraction to vision. The aim of this book is to introduce the reader to the role of sodium-calcium exchange in calcium homeostasis. Each chapter is written by a leading scientist and aims to provide a comprehensive review of a particular area in this important field. The text should be of interest to researchers in membrane transport, calcium regulation and cellular homeostasis.
The sodium-calcium exchange in intact cells, Reinaldo Dipolo;
sodium-calcium exchange activity in plasma membrane vesicles, John P.Reeves
and Kenneth D.Phillipson; sodium-calcium exchange in secretory vesicles,
T.Saermark; development and use of inhibitors to study sodium-calcium
exchange, Gregory J.Kaczorowski et al; sodium-calcium exchange in the heart,
R.A.Chapman and D.Noble; numerical probes of sodium-calcium exchange, Donald
W.Hilgemann; the molecular biochemistry of the sodium-calcium exchanger,
Hannah Rahamimoff; the electrogenic sodium-calcium exchange, D.A.Eisner and
W.J.Lederer; sodium-calcium exchange in mammalian smooth muscles, Mordecai
P.Blaustein; sodium-calcium exchange and smooth muscle function in
non-vascular smooth muscles, C.C.Aickin and A.F.Brading; comparing
sodium-calcium exchange as studied with isotopes and measurements of [ Ca]1,
L.J.Mullins and J.Requena; the sodium-calcium exchange in photoreceptors,
Leon Lagnado and Peter A.McNaughton; the role of sodium-calcium exchange in
sodium transporting epithelia, Ann Taylor.
