Stem Cell-Mediated Regulation of Pyroptosis provides a comprehensive exploration of pyroptosis, a type of programmed cell death, and its relationship with stem cells and their exosomes. The book opens by outlining the basic mechanisms of pyroptosis and detailing the most current methodologies for its detection. Emphasizing the role of stem cells in tissue repair and regeneration, especially in the context of inflammatory diseases, this work bridges foundational concepts with advanced research findings. Readers are introduced to the interplay between pyroptosis and stem cells before the discussion transitions into multiple clinical applications.
Additionally, the book examines how stem cell-mediated regulation of pyroptosis impacts a variety of conditions, including cerebral and spinal injuries, cardiac injury, osteoarthritis, and cancer. It discusses emerging therapeutic strategies and the potential for targeting the pyroptosis pathway in disease treatment. The text also provides a forward-looking perspective on future research directions, offering valuable insights for professionals in cell biology, regenerative medicine, immunology, and therapeutic development.
1. Pyroptosis: an introduction
2. Methods for comprehensive detection of pyroptosis
3. Stem cells and pyroptosis
4. Stem cells and pyroptosis in cerebral injury
5. Stem cells and pyroptosis in spinal injury
6. Stem cells and pyroptosis in cardiac injury
7. Stem cells on pyroptosis in liver injury
8. Stem cells and pyroptosis in lung injury
9. Stem cells and pyroptosis in retinal injury
10. Stem cells and pyroptosis in periodontal injury
11. Stem cells and pyroptosis in atherosclerosis
12. Stem cells and pyroptosis in osteoarthritis
13. Stem cells and pyroptosis renal injury
14. Stem cells and pyroptosis in muscle injury
15. Stem Cells and pyroptosis in cancer
Debalina Bhattacharya is currently working as an Assistant Professor in the Department of Microbiology, Maulana Azad College, West Bengal, India. Previously, she worked as a postdoctoral fellow in the Department of Biotechnology and Department of Biochemistry, University of Calcutta, West Bengal, India. She holds a PhD in bionanotechnology from Jadavpur University, West Bengal, India. She has been awarded UGC DS Kothari Post-Doctoral Fellowship in 2015 and DST-SERB National Post-Doctoral fellowship in 2018. She has co-authored 24 peer-reviewed research articles and review articles and 17 book chapters. She has also previously co-edited a book with Elsevier, "Exosomal RNA: Role in Human Diseases and Therapy". Dr. Mainak Mukhopadhyay is currently working as Associate Professor at the Department of Biosciences, JIS University, Kolkata, India. Previously, he worked as a research fellow at ONGC Energy Centre, Delhi, India. He holds a PhD in Bioenergy from the Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, India. He has been awarded the Petrotech Research Fellowship in 2008. In 2016 he was awarded the Early Career Research Award from DST-SERB. In addition to editing two books, he has co-authored 13 peer-reviewed papers, 19 book chapters and filled 3 patents. He has also co-edited another book with Elsevier, "Exosomal RNA: Role in Human Diseases and Therapy".
