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Stress Challenges and Immunity in Space: From Mechanisms to Monitoring and Preventive Strategies Softcover Reprint of the Original 1st 2012 ed. [Pehme köide]

  • Formaat: Paperback / softback, 469 pages, kõrgus x laius: 235x155 mm, kaal: 988 g, XIII, 469 p., 1 Paperback / softback
  • Ilmumisaeg: 23-Aug-2016
  • Kirjastus: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • ISBN-10: 3662502429
  • ISBN-13: 9783662502426
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  • Formaat: Paperback / softback, 469 pages, kõrgus x laius: 235x155 mm, kaal: 988 g, XIII, 469 p., 1 Paperback / softback
  • Ilmumisaeg: 23-Aug-2016
  • Kirjastus: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • ISBN-10: 3662502429
  • ISBN-13: 9783662502426
Teised raamatud teemal:
This book analyzes the interaction of living conditions in space, the immune system and astronauts' health. It explains how such analysis may help in preventing, diagnosing and counteracting immune-related alterations in health on earth as well as in space.

This book analyzes the interaction of living conditions in space, the immune system and astronauts’ health. It explains how such analysis may help in preventing, diagnosing and counteracting immune-related alterations in health on earth as well as in space.



Stress of either psychological or physical nature can activate and/or paralyse humans’ innate and adaptive immunity.  However, adequate immunity is crucial to the maintenance of health on earth and in space.  During space flight, human physiology and health are challenged by complex environmental stressors which might be at their most pronounced during lunar or interplanetary missions.  While previous publications have addressed the physiological changes that occur during space flight, this book goes further, by adopting an interdisciplinary approach to analyze the complex interaction of living conditions in space, the immune system, and astronauts’ health.  It is explained how such analysis of the consequences of stress for the immune system may help in preventing, diagnosing, and counteracting immune-related alterations in health on earth as well as in space

Part I: Prelude: A personal view from above.-A view from the ESA Topical
Team Stress and Immunity.

Part II: "Stress and Immunity"-research: a tight link between space and
earth: What is Stress? The impact of everyday stressors on the immune system
and health.

Part III: Stress & Immune Allostasis in Space, from brain to immune
responses: Neurobiological mechanisms of stress and glucocorticoid effects on
learning and memory: implications for stress disorders on earth and in
space.- The autonomous nervous system.- Circadian rhythm and stress.-
Endocannabinoids, new-old mediators of stress homeostasis.- Immune System,
definitions and stress-sensitive functions.- Innate Immunity under conditions
of space flight.-NK Cells assessments: a thirty year old History of Immune
stress interaction in Space.- Adaptive Immunity and Spaceflight.-Stress,
Hypoxia, and Immune Response.- Gravitational force triggered stress in
cells of the immune system.-Microbial Stress: Spaceflight-induced alterations
in microbial virulence and infectious disease risks for the crew.- Stress,
Spaceflight, and Latent Herpes Viruses Reactivation.- Stress and
Radiation-responsiveness.

Part IV: Preventive and Diagnostic Tool & Strategies: Consideration on
minimal or non-invasive monitoring applications.- Psychological Monitoring.-
Breath gas analyses.- Microbiological environment, complementary procedures.-
Thermoregulation.- Flow Cytometry.-  Radiation Sensitivity.

Part V: Therapeutic Strategies: Intro.- Psychological.- Physical.-
Nutrition.- Pharmacological.