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Veterinary Immunology: Principles and Practice, Second Edition 2nd edition [Pehme köide]

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  • Formaat: Paperback / softback, 336 pages, kõrgus x laius: 261x194 mm, kaal: 760 g, 328 Illustrations, color
  • Ilmumisaeg: 23-Jun-2014
  • Kirjastus: Apple Academic Press Inc.
  • ISBN-10: 1482224623
  • ISBN-13: 9781482224627
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Veterinary Immunology: Principles and Practice, Second Edition 2nd editionSuurem pilt
  • Formaat: Paperback / softback, 336 pages, kõrgus x laius: 261x194 mm, kaal: 760 g, 328 Illustrations, color
  • Ilmumisaeg: 23-Jun-2014
  • Kirjastus: Apple Academic Press Inc.
  • ISBN-10: 1482224623
  • ISBN-13: 9781482224627
Teised raamatud teemal:
Püsilink: https://www.kriso.ee/db/9781482224627.html
Märksõnad:

Veterinary Immunology: Principles and Practice has become the adopted text in numerous veterinary schools throughout the world. Widely updated with advances in knowledge since 2011, this second edition reflects the rapid development in the field.

The new edition presents expanded information on commonly used diagnostic test procedures and discusses newly arising diseases such as bovine neonatal pancytopenia. Maintaining the same reliable format as its predecessor, the book includes:

  • Learning objectives at the start of each chapter
  • Key points at the end of each chapter
  • 17 clinical case studies demonstrating clinical context for the material covered in the chapters
  • Standard symbols in diagrams throughout the text to provide continuity
  • Clinical examples and clinicopathological figures throughout
  • A glossary of terms and list of commonly used abbreviations

Exploring the immunological concerns of both large animals and small, the book emphasizes immunological principles while applying them to the disease process and to clinical practice. It provides a practical textbook for veterinary students and a handy reference for practitioners.

Arvustused

"Information is clearly presented and well written, layering immunological knowledge with each chapter. I found the chapter lengths perfect providing comprehensive information without being overwhelming. The objectives of each chapter are defined at the beginning and key points concisely reviewed at the end, allowing easy navigation and assisting comprehension. The excellent illustrations are a boon for visual learners. Immunological systems, diagnostic test procedures, clinical disease, therapy, and recent developments in the field are explored. Finally a series of case studies helps bring together and test your understanding. ... A practical textbook for students and handy reference for clinicians. ... the authors kept a challenging subject alive with analogy, illustration and clear explanations, providing a basic knowledge of immune function and clearly relating this to clinical practice. I would recommend this book to anyone challenged, intrigued or inspired by veterinary immunology." Caroline Blundell, BVetMed CertSAM RCVS, in the Journal of Feline Medicine and Surgery

"... an excellent tool to understand the basic principles of immunology and veterinary immunology. ... updated with the most recent advances in veterinary immunology developments. ... the basic knowledge provided is always practice-oriented, with practical examples on disease pathogenesis and diagnosis. This is why this book is not only a useful tool for undergraduates, but also for postgraduate veterinarians either doing a PhD, internship or residency in any area of veterinary medicine. But it is also a useful tool for veterinary clinicians who are keen to have a solid and deeper understanding of the immunology of diseases and routine procedures (such as vaccination or immunotherapy). ... The format of this book is very helpful, with a great number of illustrations and graphics that I found extremely valuable to gain understanding of difficult concepts or mechanisms, as well as the learning objectives and key points boxes in each chapter." Albert Lloret, DVM, in European Journal of Companion Animal Practice

"an excellent companion to veterinary science students in their study of immunology and for the practising veterinarian interested in gaining a greater understanding of the principles behind clinical immunology." Australian Veterinary Journal

"This is a wonderful tool, very clearly designed and beautifully illustrated.. the reader is guided very logically in a journey of discovery of the immune system and the authors are keen on explaining clearly the latest knowledge in their field" Tomorrows Vets

"The second edition of Veterinary Immunology: Principles and Practice is exactly the type of textbook necessary for teaching immunology to veterinary students. It is also an excellent reference for practitioners and residents who need to review immunology in preparation for board examinations. The format of the book is inviting, with diagrams or photographs on most pages. Tables with pertinent information are well placed and easily understood. Having taught immunology to veterinary students at the University of California -Davis for over 30 years, I appreciate the logical order in which the material is presented. ... a concise, well-written, and well-illustrated book that will be very useful for teaching veterinary immunology." Laurel J. Gershwin, DVM, PhD, DACVM, University of California-Davis, in Vet Med Today: Book Reviews, JAVMA

Foreword ix
Preface (First Edition) xi
Preface (Second Edition) xiii
Abbreviations xiv
Key to symbols xvii
Chapter 1 An overview of the immune system: innate and adaptive immunity and the inflammatory response
1(14)
Introduction
1(1)
History of immunology
1(2)
The immune system: an overview
3(9)
The evolution of the immune system
12(2)
Key points
14(1)
Chapter 2 Antigens and antibodies
15(12)
Introduction
15(1)
Antigens
15(3)
Antibodies
18(1)
Immunoglobulin classes
19(6)
Antigen-antibody interaction
25(1)
Key points
26(1)
Chapter 3 The complement system
27(12)
Introduction
27(1)
The classical and lectin pathways
28(2)
The alternative pathway
30(2)
The terminal pathway
32(1)
Biological consequences of complement activation
32(4)
Tests of complement function
36(1)
Key points
37(2)
Chapter 4 Serological testing
39(12)
Introduction
39(1)
Serological tests
40(10)
Key points
50(1)
Chapter 5 Cells and tissues of the immune system
51(20)
Introduction
51(1)
Primary lymphoid tissue
51(3)
Secondary lymphoid tissue
54(4)
Lymphocytes
58(2)
Distinguishing between immune cells
60(4)
Lymphocyte recirculation
64(5)
Mucosal lymphocyte recirculation
69(1)
Key points
70(1)
Chapter 6 The major histocompatibility complex
71(10)
Introduction
71(1)
Graft rejection
71(2)
Major histocompatibility antigens
73(1)
The major histocompatibility complex
73(2)
The inheritance of MHC
75(1)
MHC--disease associations
76(2)
Other applications of tissue typing
78(1)
Key points
79(2)
Chapter 7 Antigen presentation and cytokines
81(14)
Introduction
81(1)
Antigen presenting cells
81(3)
Antigen uptake
84(3)
Antigen processing and presentation
87(2)
Antigen presenting by CD1 molecules
89(1)
Antigen presentation by B cells and non-professional antigen presenting cells
90(1)
Cytokines
91(3)
Key points
94(1)
Chapter 8 The biology of T lymphocytes
95(18)
Introduction
95(1)
The T-cell receptor
95(3)
T-cell development and maturation
98(2)
T-cell activation
100(2)
The role of CD4+ T lymphocytes
102(3)
Cytotoxicity
105(4)
Memory cells
109(1)
γδ Lymphocytes
109(1)
Natural killer T cells
110(1)
Key points
111(2)
Chapter 9 The biology of B lymphocytes
113(12)
Introduction
113(1)
Antigen recognition by B cells
113(1)
Development and maturation of B lymphocytes
114(1)
Activation of the B lymphocyte
115(2)
B-cell receptor diversity
117(2)
The immunoglobulin class switch
119(1)
Affinity maturation
120(1)
Kinetics of the humoral immune response
120(1)
B1 and B2 lymphocytes
120(1)
Memory B lymphocytes
120(1)
Monoclonal antibodies
121(3)
Key points
124(1)
Chapter 10 Testing of cellular immune function
125(6)
Introduction
125(1)
Lymphocyte stimulation tests
125(3)
Tests of cytotoxic function
128(1)
Tests of phagocytic cell function
128(2)
Key points
130(1)
Chapter 11 Immune suppression
131(8)
Introduction
131(1)
Antigen usage
131(1)
Antibody-mediated suppression
132(1)
Immunoregulatory macrophages
133(1)
The neuroendocrine--immunological loop
133(1)
Regulatory (suppressor) T lymphocytes
134(4)
Key points
138(1)
Chapter 12 Hypersensitivity mechanisms
139(14)
Introduction
139(1)
The Gell and Coombs classification of hypersensitivity
140(1)
Type I hypersensitivity
140(3)
Type II hypersensitivity
143(2)
'type III hypersensitivity
145(3)
Type IV hypersensitivity
148(4)
Key points
152(1)
Chapter 13 The immune response to infectious agents
153(14)
Introduction
153(1)
The immune response to viral infection
153(3)
The immune response to bacterial infection
156(3)
The immune response to helminth infection
159(2)
The immune response to protozoal infection
161(2)
The immune response to fungal infection
163(2)
Key points
165(2)
Chapter 14 Cancer immunology and immune system neoplasia
167(14)
Introduction
167(1)
Tumour antigens
167(1)
The antitumour immune response
168(1)
Tumour-promoting immune activity
169(1)
Immunotherapy to enhance the antitumour immune response
170(1)
Tumours of the immune system
171(8)
Key points
179(2)
Chapter 15 Immunological tolerance
181(6)
Introduction
181(1)
Neonatal tolerance
181(1)
Adult tolerance
182(1)
Oral tolerance
182(1)
Oral tolerance as immunotherapy
183(1)
Self-tolerance
184(1)
Fetomaternal tolerance
185(1)
Key points
186(1)
Chapter 16 Autoimmunity and autoimmune disease
187(14)
Introduction
187(1)
Autoimmune disease
188(1)
The genetic basis for autoimmunity
189(1)
Age susceptibility to autoimmune disease
190(1)
Hormonal influence on autoimmunity
190(1)
Primary versus secondary autoimmune disease
190(6)
Immunodiagnostic tests for autoimmunity
196(3)
Key points
199(2)
Chapter 17 Allergy
201(12)
Introduction
201(1)
Factors predisposing to allergic disease
202(2)
The hygiene hypothesis
204(1)
Allergic disease in animals
205(5)
Diagnosis of allergic disease
210(2)
Key points
212(1)
Chapter 18 Immune system ontogeny and neonatal immunology
213(8)
Introduction
213(1)
Immune system ontogeny
213(1)
Passive transfer of maternal immune protection
213(2)
Neonatal vaccination
215(2)
Failure of passive transfer
217(1)
Primary immunodeficiency
218(1)
Neonatal isoerythrolysis
218(1)
Early life immune development
219(1)
Key points
220(1)
Chapter 19 Immunodeficiency
221(12)
Introduction
221(1)
Primary immunodeficiency
221(7)
Secondary immunodeficiency
228(3)
Key points
231(2)
Chapter 20 Vaccination
233(16)
Introduction
233(1)
Passive immunization
233(1)
Active immunization
234(1)
Infectious vaccines
235(2)
Non-infectious vaccines
237(2)
Vaccines other than for infectious disease
239(1)
Mucosal vaccines
239(1)
Needle-free vaccination
240(1)
Future vaccine developments
240(1)
Basic principles of vaccination
240(4)
Vaccine husbandry
244(1)
Adverse consequences of vaccination
244(3)
Key points
247(2)
Chapter 21 Immunotherapy
249(16)
Introduction
249(1)
Immunosuppressive agents
250(5)
Janus kinase inhibitors
255(1)
Immunostimulatory agents
255(1)
Allergen-specific immunotherapy
256(1)
Intravenous immunoglobulin therapy
257(1)
Recombinant cytokine therapy
258(1)
Cytokine gene therapy
258(1)
Monoclonal antibody therapy
259(1)
Antigen-specific immunotherapy
259(1)
Parasite therapy
260(1)
Gene therapy
260(2)
Stem cell therapy
262(1)
Adjunct immunotherapy
262(1)
Key points
263(2)
Chapter 22 Case studies in clinical immunology
265(30)
Introduction
265(1)
The basis of immune-mediated disease
265(1)
How common is immune-mediated disease?
266(1)
Immunodiagnosis
266(1)
Case 1 Canine immune-mediated haemolytic anaemia
267(2)
Case 2 Canine immune-mediated thrombocytopenia
269(2)
Case 3 Canine systemic lupus erythematosus
271(3)
Case 4 Feline blood transfusion
274(2)
Case 5 Feline multiple myeloma
276(2)
Case 6 Equine purpura haemorrhagica
278(1)
Case 7 Bovine thymic lymphoma
279(1)
Case 8 Canine atopic dermatitis
280(1)
Case 9 Equine severe combined immunodeficiency
281(1)
Case 10 Canine lymphocytic thyroiditis
282(2)
Case 11 Canine immune-mediated polyarthritis
284(2)
Case 12 Bovine allergic rhinitis
286(1)
Case 13 Canine drug reaction
287(2)
Case 14 Canine trapped neutrophil syndrome
289(1)
Case 15 Feline lymphoid leukaemia
290(2)
Case 16 Equine neonatal isoerythrolysis
292(1)
Case 17 Immunological aspects of a herd outbreak of bovine viral diarrhoea virus infection
293(2)
Glossary 295(14)
Index 309