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xi |
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Foreword |
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xii |
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ICD-0 topographical coding |
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1 |
(1) |
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ICD-0 morphological coding |
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1 |
(6) |
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2 |
(5) |
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1 Introduction to CNS tumours |
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7 |
(8) |
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2 Gliomas, glioneuronal tumours, and neuronal tumours |
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15 |
(174) |
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16 |
(3) |
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Adult-type diffuse gliomas Astrocytoma, IDH-mutant |
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19 |
(37) |
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Oligodendroglioma, IDH-mutant and 1p/19q-codeleted |
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28 |
(11) |
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Glioblastoma, IDH-wildtype |
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39 |
(17) |
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Paediatric-type diffuse low-grade gliomas Diffuse astrocytoma, MYB- or MYBL1-altered |
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56 |
(13) |
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59 |
(3) |
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Polymorphous low-grade neuroepithelial tumour of the young |
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62 |
(3) |
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Diffuse low-grade glioma, MAPK pathway-altered |
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65 |
(4) |
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Paediatric-type diffuse high-grade gliomas Diffuse midline glioma, H3 K27-altered |
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69 |
(14) |
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Diffuse hemispheric glioma, H3 G34-mutant |
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74 |
(3) |
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Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype |
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77 |
(4) |
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Infant-type hemispheric glioma |
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81 |
(2) |
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Circumscribed astrocytic gliomas Pilocytic astrocytoma |
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83 |
(28) |
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High-grade astrocytoma with piloid features |
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90 |
(4) |
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Pleomorphic xanthoastrocytoma |
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94 |
(6) |
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Subependymal giant cell astrocytoma |
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100 |
(4) |
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104 |
(3) |
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Astroblastoma, MN1-altered |
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107 |
(4) |
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Glioneuronal and neuronal tumours Ganglioglioma |
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111 |
(48) |
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116 |
(3) |
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Desmoplastic infantile ganglioglioma /desmoplastic infantile astrocytoma |
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119 |
(4) |
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Dysembryoplastic neuroepithelial tumour |
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123 |
(4) |
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Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters |
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127 |
(3) |
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Papillary glioneuronal tumour |
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130 |
(3) |
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Rosette-forming glioneuronal tumour |
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133 |
(3) |
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Myxoid glioneuronal tumour |
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136 |
(3) |
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Diffuse leptomeningeal glioneuronal tumour |
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139 |
(4) |
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Multinodular and vacuolating neuronal tumour |
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143 |
(3) |
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Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) |
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146 |
(3) |
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149 |
(4) |
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Extraventricular neurocytoma |
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153 |
(3) |
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Cerebellar liponeurocytoma |
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156 |
(3) |
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Ependymal tumours Introduction |
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159 |
(30) |
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Supratentorial ependymoma |
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161 |
(3) |
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Supratentorial ependymoma, ZFTA fusion-positive |
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164 |
(3) |
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Supratentorial ependymoma, YAPI fusion-positive |
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167 |
(2) |
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Posterior fossa ependymoma |
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169 |
(3) |
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Posterior fossa group A (PFA) ependymoma |
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172 |
(3) |
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Posterior fossa group B (PFB) ependymoma |
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175 |
(2) |
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177 |
(3) |
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Spinal ependymoma, MYCN-amplified |
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180 |
(3) |
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183 |
(3) |
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186 |
(3) |
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189 |
(10) |
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190 |
(3) |
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Atypical choroid plexus papilloma |
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193 |
(2) |
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195 |
(4) |
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199 |
(42) |
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Medulloblastoma Introduction |
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200 |
(3) |
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Medulloblastomas, molecularly defined Medulloblastoma, WNT-activated |
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203 |
(17) |
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Medulloblastoma, SHH-activated and TP53-wildtype |
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205 |
(3) |
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Medulloblastoma, SHH-activated and TP53-mutant |
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208 |
(3) |
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Medulloblastoma, non-WNT/non-SHH |
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211 |
(2) |
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Medulloblastomas, histologically defined Medulloblastoma, histologically defined |
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213 |
(7) |
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Other CNS embryonal tumours Introduction |
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220 |
(21) |
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Atypical teratoid/rhabdoid tumour |
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221 |
(5) |
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Cribriform neuroepithelial tumour |
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226 |
(2) |
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Embryonal tumour with multilayered rosettes |
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228 |
(4) |
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CNS neuroblastoma, FOXR2-activated |
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232 |
(3) |
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CNS tumour with BCOR internal tandem duplication |
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235 |
(3) |
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CNS embryonal tumour NEC/NOS |
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238 |
(3) |
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241 |
(18) |
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242 |
(1) |
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243 |
(3) |
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Pineal parenchymal tumour of intermediate differentiation |
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246 |
(3) |
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249 |
(4) |
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Papillary tumour of the pineal region |
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253 |
(3) |
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Desmoplastic myxoid tumour of the pineal region, SMAflCB 7-mutant |
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256 |
(3) |
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6 Cranial and paraspinal nerve tumours |
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259 |
(24) |
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260 |
(1) |
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261 |
(4) |
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265 |
(4) |
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269 |
(2) |
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Hybrid nerve sheath tumours |
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271 |
(2) |
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Malignant melanotic nerve sheath tumour |
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273 |
(2) |
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Malignant peripheral nerve sheath tumour |
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275 |
(4) |
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Cauda equina neuroendocrine tumour (previously paraganglioma) |
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279 |
(4) |
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283 |
(16) |
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8 Mesenchymal, non-meningothelial tumours involving the CNS |
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299 |
(40) |
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300 |
(1) |
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Fibroblastic and myofibroblastic tumours Solitary fibrous tumour |
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301 |
(5) |
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Vascular tumours Haemangiomas and vascular malformations |
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306 |
(4) |
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310 |
(4) |
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Skeletal muscle tumours Rhabdomyosarcoma |
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314 |
(3) |
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Tumours of uncertain differentiation Intracranial mesenchymal tumour, FET::CREB fusion-positive |
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317 |
(3) |
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320 |
(3) |
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Primary intracranial sarcoma, D/CER7-mutant |
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323 |
(3) |
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326 |
(4) |
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Chondro-osseous tumours Chondrogenic tumours Mesenchymal chondrosarcoma |
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330 |
(9) |
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332 |
(3) |
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Notochordal tumours Chordoma |
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335 |
(4) |
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339 |
(10) |
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340 |
(1) |
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Diffuse meningeal melanocytic neoplasms Melanocytosis and melanomatosis |
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341 |
(3) |
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Circumscribed meningeal melanocytic neoplasms Melanocytoma and melanoma |
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344 |
(5) |
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10 Haematolymphoid tumours involving the CNS |
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349 |
(32) |
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350 |
(1) |
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Lymphomas CNS lymphomas Primary diffuse large B-cell lymphoma of the CNS |
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351 |
(11) |
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Immunodeficiency-associated CNS lymphomas |
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356 |
(2) |
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Lymphomatoid granulomatosis |
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358 |
(2) |
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Intravascular large B-cell lymphoma |
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360 |
(2) |
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Miscellaneous rare lymphomas in the CNS MALT lymphoma of the dura |
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362 |
(8) |
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Other low-grade B-cell lymphomas of the CNS |
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364 |
(2) |
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Anaplastic large cell lymphoma (ALK+/ALK-) |
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366 |
(2) |
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T-cell and NK/T-cell lymphomas |
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368 |
(2) |
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Histiocytic tumours Erdheim-Chester disease |
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370 |
(11) |
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372 |
(2) |
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374 |
(2) |
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Langerhans cell histiocytosis |
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376 |
(3) |
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379 |
(2) |
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381 |
(10) |
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12 Tumours of the sellar region |
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391 |
(26) |
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392 |
(1) |
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Adamantinomatous craniopharyngioma |
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393 |
(4) |
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Papillary craniopharyngioma |
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397 |
(4) |
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Pituicytoma, granular cell tumour of the sellar region, and spindle cell oncocytoma |
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401 |
(5) |
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Pituitary adenoma / pituitary neuroendocrine tumour |
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406 |
(9) |
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415 |
(2) |
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417 |
(6) |
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Metastases to the brain and spinal cord parenchyma |
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418 |
(3) |
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Metastases to the meninges |
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421 |
(2) |
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14 Genetic tumour syndromes involving the CNS |
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423 |
(60) |
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424 |
(2) |
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426 |
(3) |
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429 |
(5) |
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434 |
(3) |
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Von Hippel-Lindau syndrome |
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437 |
(4) |
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441 |
(5) |
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446 |
(3) |
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449 |
(3) |
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Constitutional mismatch repair deficiency syndrome |
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452 |
(4) |
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Familial adenomatous polyposis 1 |
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456 |
(2) |
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Naevoid basal cell carcinoma syndrome |
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458 |
(2) |
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Rhabdoid tumour predisposition syndrome |
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460 |
(2) |
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462 |
(2) |
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464 |
(3) |
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Familial paraganglioma syndromes |
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467 |
(4) |
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Melanoma-astrocytoma syndrome |
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471 |
(2) |
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473 |
(2) |
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BAP1 tumour predisposition syndrome |
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475 |
(3) |
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478 |
(3) |
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ELP1-medulloblastoma syndrome |
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481 |
(2) |
Contributors |
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483 |
(6) |
Declaration of interests |
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489 |
(2) |
IARC/WHO Committee for ICD-O |
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491 |
(2) |
Sources |
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493 |
(8) |
References |
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501 |
(56) |
Subject index |
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557 |
(11) |
Previous volumes in the series |
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568 |
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