The effect of xenobiotics on general host resistance and on specific immune functions has recently become the focus of much research. Xenobiotics and Inflammation synthesizes current information on how chemicals (xenobiotics) can modulate the immune system, focusing on the process of inflammation. It provides a much needed, single-source reference for researchers investigating the mechanisms responsibIe for altered host resistance following exposure to xenobiotics. Emphasis is on the roles of cytokines and growth factors in the inflammatory process and how production of these mediators is modified by xenobiotics. Researchers exploring cell growth, angiogenesis, hematopoetic differentiation, and recruitment to and proliferation of cells in various tissue sites will find this book timely and useful. The editors have brought together experts in inflammation, cytokines, cell growth, immunology, and toxicology to provide a highly useful volume. Divided into three sections, the book offers an organ system approach to understanding inflammatory and xenobiotics.
Focusing on inflammation, and particularly on the role of cytokines and growth factors, explores how chemicals can modulate the immune system. Among the topics are the effects of metals on lymphocyte development and function, xenobiotic-induced skin toxicity, and ozone-induced inflammatory response in pulmonary cells. Annotation copyright Book News, Inc. Portland, Or.
