Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the...Loe edasi...
The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers includ...Loe edasi...
(Ilmumisaeg: 13-Oct-2023, Hardback, Kirjastus: Springer International Publishing AG, ISBN-13: 9783031426476)
Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the...Loe edasi...
(Ilmumisaeg: 02-Sep-2023, Hardback, Kirjastus: Springer International Publishing AG, ISBN-13: 9783031400469)
The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers includ...Loe edasi...
Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of p...Loe edasi...
The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bo...Loe edasi...
The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial l...Loe edasi...
Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, fro...Loe edasi...
This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulati...Loe edasi...
Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of p...Loe edasi...
(Ilmumisaeg: 07-Jul-2022, Hardback, Kirjastus: Springer International Publishing AG, ISBN-13: 9783031051173)
The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bo...Loe edasi...
(Ilmumisaeg: 07-Jun-2022, Hardback, Kirjastus: Springer International Publishing AG, ISBN-13: 9783031065118)
The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial l...Loe edasi...
Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game change...Loe edasi...
This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume Atherosclerosis: Diet and Drugs reflects the state-of-the-art and most re...Loe edasi...
This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume Atherosclerosis: Diet and Drugs reflects the state-of-the-art and most re...Loe edasi...
This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bon...Loe edasi...
Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, fro...Loe edasi...
This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulati...Loe edasi...
This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory a...Loe edasi...
Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases...Loe edasi...