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E-raamat: Sex and Gender Effects in Pharmacology

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Sex and Gender Effects in PharmacologySuurem pilt
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Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
Part 1 Pharmacological Basic Principles .- The impact of sex and gender
in medicine and pharmacology.- Sex differences in pharmacokinetics.- Clinical
pharmacological considerations in transgender medicine.- Sex and gender
differences in the pharmacology of the overactive urinary bladder.- Part 2
Pathologies of the Brain.- Sex differences in the evaluation and treatment of
stroke.- Sex differences in pain and its treatment.- Therapeutics For
Substance-Using Women: The Need To Elucidate Sex-Specific Targets For
Better-Tailored Treatments.- Intersection of sex and depression:
pathogenesis, presentation and treatments.- Biological and clinical
implications of sex-specific differences in Alzheimers disease.- Part 3
Diabetes, metabolic diseases & cardiovascular risk.- Gender Differences In
Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management.
- Sex Differences in Glucose Homeostasis.- Sex-gender-based differences in
metabolic diseases.- Hypothalamic pituitary gonadal axis disorders impacting
fertility in both sexes and the potential of kisspeptin-based therapies to
treat them.
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Püsilink: https://www.kriso.ee/db/97830314264836e.html
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