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Clinical Neurovirology 2nd edition [Kõva köide]

Edited by (Nat. Inst. of Health, USA), Edited by (University of Pennsylvania, Philadelphia, USA)
  • Formaat: Hardback, 452 pages, kõrgus x laius: 280x210 mm, kaal: 1632 g, 2 Tables, color; 54 Tables, black and white; 31 Illustrations, color; 63 Illustrations, black and white
  • Ilmumisaeg: 14-May-2020
  • Kirjastus: CRC Press Inc
  • ISBN-10: 1498733166
  • ISBN-13: 9781498733168
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  • Formaat: Hardback, 452 pages, kõrgus x laius: 280x210 mm, kaal: 1632 g, 2 Tables, color; 54 Tables, black and white; 31 Illustrations, color; 63 Illustrations, black and white
  • Ilmumisaeg: 14-May-2020
  • Kirjastus: CRC Press Inc
  • ISBN-10: 1498733166
  • ISBN-13: 9781498733168
Teised raamatud teemal:
This is a comprehensive reference that includes the basic science, clinical features, imaging, pathology and treatment of specific viral entities affecting the central nervous system (CNS). It will assist professionals in their attempt to identify, examine and manage viral CNS infections and unravel the therapeutic and diagnostic challenges associated with viral CNS disorders.

Key Features











Features MRI scans, histopathology and lined diagrams showing pathophysiology





Much has happened in our understanding of CNS infections in recent years and a comprehensive book that covers the entire subject is much needed.





There is ongoing interest in infectious disease. The increasing globalization of medicine is putting demands on many more people to become familiar with issues from around that world that they did not see in training.

Arvustused

This second edition is a wonderful comprehensive reference for practicing neurologists and infectious disease specialists when faced with patients afflicted with viral-mediated neurological syndromes. A significant upgrade from the first edition, this edition includes newer topics, including West Nile, Ebola, Zika, enterovirus D68, and SARS-CoV-2 viruses, as well as significant advances in methodologies of detection and treatment. Drs. Nath and Berger have provided a very broad coverage to this topic, reflecting their clinical and scientific background, keeping both the clinical and scientific practitioners in mind. This text holds its own as a solidly comprehensive reference text for clinicians, including neurologists and infectious disease specialists, as well as for the immunologist and clinical scientist involved in the pathophysiology of virally mediated neurological illnesses. The editors are well-renowned neuroinfectious specialists in theirnfield who have sought experts from around the world to help contribute chapters to this text. There is a lack of textbooks in this area, and having an authoritative work helps the field progress further, especially with the advances made since the last edition was published in 2003.

Ali A Saherwala, MD(Thomas Jefferson University)

Preface ix
Acknowledgments xi
Editors xiii
Contributors xv
Part I Introduction: Epidemiology, Socioeconomic Impact, And Challenges Ahead 1(42)
1 Introduction to virus structure, classification, replication, and hosts
3(14)
Philippe Simon
Kevin M. Coombs
2 Neuropathogenesis of viral infections
17(10)
Avindra Nath
Joseph R. Berger
3 An approach to pathogen discovery for viral infections of the nervous system
27(8)
Prashanth S. Ramachandran
Michael R. Wilson
4 Neuropathology of CNS viral infections and the role of brain biopsy in the diagnosis
35(8)
Susan Morgello
Part II DNA Viruses 43(110)
5 Herpes simplex viruses
45(14)
Israel Steiner
Felix Benninger
6 Varicella zoster virus infection
59(14)
Don Gilden
Randall J. Cohrs
Dallas Jones
Maria A. Nagel
7 Epstein-Barr virus and the nervous system
73(16)
Alexandros C. Tselis
Kumar Rajamani
Pratik Bhattacharya
8 Cytomegalovirus
89(20)
Joseph R. Berger
9 Progressive multifocal leukoencephalopathy
109(32)
Eric M.L. Williamson
Joseph R. Berger
10 Adenovirus
141(12)
Jennifer McGuire
Joseph R. Berger
Part III Retroviruses 153(32)
11 HIV neurological complications
155(22)
Alessandro Fois
Bruce Brew
12 Human T lymphotropic virus type 1 (HTLV-1)
177(8)
Shila Azodi
Steven Jacobson
Part IV RNA Viruses 185(150)
13 Rabies and other lyssaviruses
187(38)
Thiravat Hemachudha
Jiraporn Laothamatas
Henry Wilde
14 Neurological manifestations of West Nile virus
225(12)
Daniel E. Smith
J. David Beckham
Daniel M. Pastula
Kenneth L. Tyler
15 Chikungunya virus and Japanese encephalitis virus
237(12)
Jennifer L. Lyons
16 Arthropod-borne virus encephalitis
249(24)
Joseph R. Berger
17 Enteroviruses
273(14)
Karen Straube-West
Burk Jubelt
18 Measles and its neurological complications
287(20)
Benedikt Weissbrich
Jurgen Schneider-Schaulies
19 Rubella
307(6)
Avindra Nath
20 Influenza neurologic complications
313(16)
Larry E. Davis
Jennifer R. Plourde
21 Nipah encephalitis, a fatal encephalitis with bats as reservoir
329(6)
Chong-Tin Tan
Kum-Thong Wong
Part V Miscellaneous 335(108)
22 Von Economo's encephalitis
337(14)
Joseph R. Berger
23 Neurological events following immunizations
351(14)
James J. Sejvar
24 Central nervous system viral infections complicating immunosuppression
365(16)
Amy A. Pruitt
25 Post-viral syndromes
381(12)
Anusha K. Yeshokumar
Eliza Gordon-Lipkin
Brenda Banwell
26 Viral neuro-oncogenesis: Polyomaviruses and brain tumors
393(16)
Martyn K. White
Sidney E. Croul
Kamel Khalili
27 Autoimmune disorders that can be mistaken for viral illness
409(14)
Maxwell Greene
Eric Lancaster
28 Antiviral therapeutics for viral infections of the central nervous system
423(16)
Richard Whitley
29 Neurological manifestations of coronavirus infections
439(4)
Avindra Nath
Joseph R. Berger
Index 443
Avindra Nath

Dr. Nath is the Chief of the Section of Infections of the Nervous System at the National Institute of Neurological Disorders and Stroke. He was previously Professor in the Department of Neurology and Director of the Division of Neuroimmunology and Neurological Infections at Johns Hopkins University. His career has been dedicated to studying the clinical manifestations, pathophysiology and developing treatment for brain infections since the beginning of the AIDS pandemic. He has traveled to several countries to study these infections including Liberia during the Ebola epidemic. He teaches medical students, residents and clinical fellows on CNS infections for which he has received several teaching awards. He frequently talks at grand rounds, seminars and conferences around the world on viral infections of the brain and has been teaching courses on viral encephalitis at the American Academy of Neurology for over 20 years. His laboratory research is focused mainly on retroviral infections particularly HIV infection. More recently, his laboratory is studying the pathophysiology of Ebola and Zika viruses. He is the past President of the International Society of Neurovirology (ISNV) and an elected member of the Association of American Physicians. He is the recipient of the Pioneer award from the ISNV and the Wybran award from the Society of Neuroimmune Pharmacology.

Joseph R. Berger

Dr. Berger, M.D., is Professor of Neurology and Associate Chief of the Multiple Sclerosis Division of the Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia. His career has been dedicated to the diagnosis, treatment and investigation of neuroinfectious and neuroinflammatory disorders. His foray into neuroinfectious diseases started with the investigation of the neurological complications of HIV/AIDS while at the University of Miami at the inception of the AIDS pandemic and an endowment there established the Whigham-Berger Endowed Chair, the first endowed chair for the study of the neurological complications of HIV/AIDS. Dr. Berger continued his research in HIV and PML while at the University of Kentucky where he was Chairman of the Department of Neurology from 1995 to 2013. With Dr. Robert Levy, he co-founded and co-chaired the international Neuroscience of HIV conference. He is a fellow of the American College of Physicians, American Academy of Neurology and the American Neurological Association. Among his many awards are the Pioneer Award from the International Society of Neurovirology and the Distinguished Teaching Award from the American Neurological Association.