Fibroblast growth factors (FGFs) are secreted protein ligands that act in a paracrine or endocrine fashion to carry out their pleiotropic functions in development, tissue homeostasis and metabolism. Especially in recent years, more and more attention has been paid to this super family. In the past 30 years, Prof. Xiaokun Li’s research team has been focused on the field of basic mechanism and bioengineering of FGFs in China. This book is the second version which collected research results of Li’s team from 2013 to 2018. All these 9 chapters spans reviews of FGFs, injury repair and regeneration, metabolism, structure and modification, signaling pathway and pharmacology, pharmaceutics and new materials, bioreactor and engineering as well as FGF/FGFR inhibitors and others. This work should be a helper primer to scientists and particularly young students entering the FGFs field with their eye toward basic research and application.
The book contains nine chapters, systematically introducing readers to FGF, in the fields of injury repair and regeneration, endocrinology and metabolism, structure and modification, pharmaceutics, pharmacology, FGF/FGFR inhibitor, engineering and new drug development.
- Since the publication of the first edition of this book, Professor Li and his team have expanded their research considerably and this is reflected in the second edition, which contains approximately 90% new material
- The book contains information on “breakthrough discoveries which have been made since publication of the first edition
- Introduces detailed research methods and technologies of FGFs, so it can be used as a “toolbox by the user
- Is comprehensive and systematic: providing all-round view of FGF, including basic research and industry application
