Contributors |
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ix | |
Preface |
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xi | |
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2 | (1) |
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2 Forward Genetics: From Large Screens to Targeted Screens |
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3 | (1) |
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3 Reverse Genetics: Morpholino Knockdowns |
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4 | (4) |
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4 Reverse Genetics: TILLING |
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8 | (2) |
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5 Reverse Genetics: Zinc Finger Nucleases |
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10 | (3) |
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6 Gain of Function: Targeted Misexpression of Genes |
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13 | (3) |
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7 Genetic Ablation of Specific Cell Population |
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16 | (2) |
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18 | (8) |
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2 Organization and Physiology of the Zebrafish Nervous System |
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26 | (3) |
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2 Nervous System Development and General Organization |
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29 | (6) |
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3 General Organization of the Zebrafish Nervous System, Subdivisions and Main Functions |
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35 | (9) |
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4 The Peripheral Nervous System |
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44 | (3) |
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47 | (3) |
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6 Motor Systems and Integrative Centers |
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50 | (1) |
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7 Monoaminergic and Related Regulatory Systems |
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51 | (4) |
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55 | (7) |
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9 Nervous System Plasticity |
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62 | (20) |
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3 Zebrafish Vision: Structure and Function of the Zebrafish Visual System |
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82 | (1) |
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2 Structure of the Visual System |
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82 | (13) |
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95 | (2) |
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97 | (2) |
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99 | (10) |
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6 Complex Visual Behavior |
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109 | (2) |
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111 | (13) |
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4 The Zebrafish Inner Ear |
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124 | (3) |
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2 Development of the Inner Ear |
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127 | (7) |
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3 Generation and Homeostasis of Endolymph in the Zebrafish Inner Ear |
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134 | (3) |
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4 Zebrafish Sensory Hair Cells |
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137 | (4) |
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141 | (3) |
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144 | (3) |
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147 | (9) |
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156 | (4) |
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160 | (14) |
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5 Endocrinology of Zebrafish: A Small Fish with a Large Gene Pool |
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174 | (1) |
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175 | (37) |
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3 Stress: The Cortisol Stress Axis |
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212 | (2) |
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214 | (7) |
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221 | (2) |
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6 Energy Homeostasis: Food Intake and Metabolism |
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223 | (6) |
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229 | (3) |
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232 | (18) |
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6 Developmental Physiology of the Zebrafish Cardiovascular System |
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1 Cardiovascular Disease: Models Wanted |
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250 | (1) |
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2 Current Models for Cardiovascular System Studies |
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251 | (1) |
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3 Filling a Niche with Zebrafish |
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252 | (1) |
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4 Unique Advantages of the Zebrafish for Cardiovascular Studies |
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252 | (1) |
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5 Vertebrate Cardiac Development |
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253 | (1) |
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6 Origin and Lineage of Cells in the Cardiovascular System |
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253 | (1) |
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7 Zebrafish Genetics and Development of the Cardiovascular System |
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254 | (1) |
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8 Genetic Infrastructure and Tools for Zebrafish Studies |
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255 | (1) |
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9 Zebrafish Cardiovascular Mutants |
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255 | (3) |
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10 Mutants Affecting Rate, Rhythm and Contractile Properties of the Heart |
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258 | (2) |
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11 Relationship Between Cardiovascualr Function and Form |
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260 | (1) |
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12 Endothelial Cell Specification and Differentiation |
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261 | (1) |
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13 Specification of Artery and Vein |
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261 | (2) |
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14 Cell Migration of Angioblasts and Vascular Patterning |
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263 | (1) |
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15 Angiogenesis of the Intersegmental Vessels |
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264 | (1) |
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16 Lumenization of Vessels |
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264 | (1) |
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17 Vascular Stabilization, Mural Cells, and Extracellular Matrix |
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265 | (1) |
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18 Angiogenesis of Organs |
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266 | (2) |
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19 Chemical Biology Approaches to Study Cardiovascular Biology |
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268 | (1) |
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20 Forces that Influence Cardiovascular Development |
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269 | (4) |
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21 Endothelial Cell Survival |
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273 | (1) |
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22 Zebrafish Models for Vascular Anomalies |
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273 | (1) |
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23 Tools for the Study of Cardiovascular Physiology |
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274 | (1) |
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275 | (1) |
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276 | (1) |
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277 | (13) |
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290 | (1) |
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2 The Principles of Gas Exchange |
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291 | (2) |
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3 The Site of Gas Exchange |
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293 | (3) |
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296 | (3) |
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299 | (2) |
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301 | (2) |
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303 | (2) |
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305 | (7) |
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8 Ionic and Acid---Base Regulation |
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312 | (1) |
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2 Identification of Ionocytes in Skin/gills |
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313 | (2) |
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3 Sodium Uptake and Acid Secretion by Skin/gills |
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315 | (5) |
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4 Chloride Uptake and Base Excretion |
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320 | (2) |
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322 | (1) |
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323 | (2) |
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7 Differentiation and Functional Regulation of Ionocytes |
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325 | (5) |
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8 Neuroendocrine Control of Ion Uptake and Acid-Base Regulation |
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330 | (2) |
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9 Renal Ionic and Acid Base Regulation |
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332 | (2) |
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10 Conclusions and Perspectives |
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334 | (12) |
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9 The Zebrafish as a Model for Human Disease |
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346 | (1) |
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347 | (5) |
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3 Hematopoictic Disorders |
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352 | (5) |
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4 Cardiovascular Diseases |
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357 | (2) |
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5 Chemical Screening in Zebrafish |
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359 | (3) |
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362 | (6) |
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10 Perspectives on Zebrafish as a Model in Environmental Toxicology |
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368 | (2) |
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2 Current Issues in Environmental Toxicology |
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370 | (3) |
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3 The Zebrafish Toxicology Landscape: Emergence of a New Model |
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373 | (2) |
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4 Molecular Environmental Toxicology: The Defensome Concept |
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375 | (19) |
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5 Advances and Insights with Zebrafish |
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394 | (12) |
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6 Toxicity and Environmental Assessment with Zebrafish |
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406 | (5) |
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7 Areas of Looming Significance and Promising Approaches |
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411 | (8) |
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419 | (22) |
Index |
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441 | (12) |
Other Volumes in the Fish Physiology Series |
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453 | |