Assessment of liver disease severity.- Hepatitis C and autoimmunity.- Extrahepatic manifestations.- Treatment indications and pretreatment assessment.- Available agents - contraindications and potential drug-drug interactions.- Current management of patients with HCV genotype 1.- Current management of patients with HCV genotype 2.- Current management of patients with HCV genotype 3.- Current management of patients with HCV genotype 4.- Current management of patients with HCV genotype 5 or 6.- The role of RAVs in the current management of HCV.- Management of patients with HCV decompensated cirrhosis.- Management of patients with acute hepatitis C.- Management of transplant patients.- Management of immune complex-mediated manifestations of HCV.- Management of patients with co-infections (HBV, HIV).- Management of patients under hemodialysis.-Management of active drug addicts or patients on maintenance substitution.- Management of patients with hemoglobinopathies or bleeding disorders.- Follow-up during and after treatment.