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Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice [Pehme köide]

(Ghent University, Belgium)
  • Formaat: Paperback / softback, 210 pages, kõrgus x laius: 229x152 mm, kaal: 350 g
  • Ilmumisaeg: 26-Nov-2018
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0128146125
  • ISBN-13: 9780128146125
Teised raamatud teemal:
  • Formaat: Paperback / softback, 210 pages, kõrgus x laius: 229x152 mm, kaal: 350 g
  • Ilmumisaeg: 26-Nov-2018
  • Kirjastus: Academic Press Inc
  • ISBN-10: 0128146125
  • ISBN-13: 9780128146125
Teised raamatud teemal:

Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice covers the complete aspects of lung function testing, ranging from standardized to newly introduced (IOS, FOT) methods. It provides an updated overview of advances in respiratory engineering, along with advice on which lung function tests are appropriate for which purpose. The author discusses non-standardized lung function testing, methods, clinical tests, diagnosis and future perspectives. Lung function measurement devices and protocols are also covered. This book covers multidisciplinary domains, bringing new technology ideas from mathematics, physics, biology and engineering into the field of respiratory engineering.

Users will find a single resource that brings together all of the disparate information on lung function testing technology currently contained in many journal articles.

  • Bridges the gap between engineers and clinicians with regard to pulmonary function techniques, from research, to design and clinical practice
  • Provides a comprehensive overview of all tools available for lung function testing, detailing their pros and cons
  • Includes information on incorporating new devices into existing procedures, along with methods for lung function testing
About the Contributors ix
Preface xiii
Acknowledgment xv
1 Introduction
1(4)
Clara M. Ionescu
Generic Context
1(2)
About This Book
3(1)
Beyond This Book
4(1)
References
4(1)
2 Standardized Pulmonary Function Testing
5(20)
Ubong Peters
David A. Kaminsky
Geoff N. Maksym
Spirometry
5(8)
Assessment of Bronchial Reversibility With Spirometry
8(1)
Assessment of Airway Hyperresponsiveness With Spirometry
9(2)
Limitations of Spirometry
11(2)
Body Plethysmography
13(4)
Summary
17(1)
Grants
18(1)
References
18(7)
3 Oscillometry for Lung Function Testing
25(84)
Ubong Peters
David A. Kaminsky
Swati Bhatawadekar
Lennart Lundblad
Geoff N. Maksym
History and Development of the Forced Oscillation Technique
25(1)
Principles of Measurement
26(3)
Types of Oscillatory Waveforms
29(1)
Data Acquisition and Processing
30(1)
Modeling of Lung Mechanics
30(1)
Important Measurement Precautions
31(2)
Clinical Application of Oscillometry
33(2)
Clinical Utility of Rrs and Rrs-Derived Indices
35(1)
Correlation Between Rrs and Other Measures of Lung Function and Quality of Life
36(2)
Clinical Utility of Xrs and Xrs-Derived Indices
38(1)
Correlation Between Xrs and FEV,, Symptoms, Severity and Control, and Quality of Life Outcomes
39(1)
Limitations of Oscillometry
40(2)
Summary
42(1)
Table of Symbols and Acronyms
42(1)
References
43(6)
3.1 Nonstandardized Lung Function Tests
49(2)
Ireneusz Jablonski
The Airflow Interrupter Technique
51(18)
Measurement Setup Used in Interrupter Lung Function Testing
53(2)
Interrupter Valve---Guide Points for Key Hardware Enabler in Interrupter Technique Measurement
55(4)
Algorithms of Postocclusional Data Processing
59(10)
Impulse Oscillometry
69(6)
Measurement Setup Used in Impulse Oscillometry
70(1)
Algorithms of the Oscillatory Data Processing
71(4)
Summary
75(1)
Acknowledgements
76(1)
References
76(5)
3.2 Oscillometry for Lung Function Testing
81(1)
Ubong Peters
David A. Kaminsky
Swati Bhatawadekar
Lennart Lundblad
Geoff N. Maksym
History and Development of the Forced Oscillation Technique
81(1)
Principles of Measurement
82(3)
Types of Oscillatory Waveforms
85(1)
Data Acquisition and Processing
86(1)
Modeling of Lung Mechanics
86(3)
Important Measurement Precautions
89(2)
Clinical Application of Oscillometry
91(7)
Clinical Utility of Rrs and Rrs-Derived Indices
91(3)
Correlation Between Rrs and Other Measures of Lung Function and Quality of Life
94(1)
Clinical Utility of Xrs and Xrs-Derived Indices
95(2)
Correlation between Xrs and FEV1, symptoms, severity and control, and quality of life outcomes
97(1)
Limitations of Oscillometry
98(2)
Summary
100(1)
Table of Symbols and Acronyms
101(1)
Acknowledgments
101(1)
References
102(7)
4 Information From Time-Based Signals
109(16)
Cristina I. Muresan
Dana Copot
Stress and Strain Curves
109(5)
Basic Elements
109(3)
Viscoelasticity in the Lungs
112(2)
Models for Evaluating Respiratory Properties
114(3)
Integer-Order Impedance Models
114(2)
Fractional Order Impedance Models
116(1)
Heterogeneity and Nonlinearity in the Lung Tissue
117(5)
Acknowledgments
122(1)
References
123(2)
5 Diffusion
125(38)
5.1 Diffusion in Small Airways
127(1)
Dana Copot
Evaluating and Modeling Diffusion
127(11)
Generic Models of Diffusion Through Porous Media
127(6)
Molecular Diffusion
133(3)
Gas Diffusion Through the Respiratory Membrane
136(2)
Effects of Geometry and Porosity on Diffusion
138(12)
Structural Changes in Chronic Obstructive Pulmonary Disease
138(2)
Diffusion at Low Frequencies
140(6)
Evaluating Nonlinear Diffusion Effects in Patients With COPD
146(4)
Acknowledgments
150(1)
References
150(3)
5.2 The Multiple-Breath Nitrogen Washout Test
153(1)
Ubong Peters
David A. Kaminsky
History and Development of the Multiple-Breath Nitrogen Washout Test
153(1)
Measurement Principles
154(5)
Physiological Interpretation and Clinical Utility of Washout Outcomes
159(1)
Important Measurement Considerations
160(1)
Strengths and Weaknesses
161(1)
Conclusions
161(1)
Grants
161(1)
Acknowledgments
161(1)
References
161(2)
6 Added Value of Other Clinical Tests
163(8)
Clara M. Ionescu
Computed Tomography Scans
163(1)
Sound-Based Diagnosis
164(3)
Electrical Impedance Tomography
166(1)
References
167(4)
7 Diagnosis of Asthma and Chronic Obstructive Pulmonary Disease
171(14)
Eric Derom
Clara M. Ionescu
Asthma and Chronic Obstructive Pulmonary Disease Phenotypes
171(5)
Asthma----Chronic Obstructive Pulmonary Disease Overlap Phenotype
173(1)
Frequent Exacerbator Phenotype
173(1)
Upper Lobe-Predominant Emphysema Phenotype
174(1)
Rapid Decliner Phenotype
174(1)
Comorbid Phenotype
174(1)
Physical Frailty Phenotype
174(1)
Emotional Frailty Phenotype
174(2)
Which Lung Function Tests for Which Purpose
176(2)
Patient Monitoring and Management
178(3)
References
181(4)
8 Perspectives
185(4)
Clara M. Ionescu
Index 189
Prof. Dr. Clara Mihaela Ionescu is the holder of the Flanders Research Foundation FWO post-doctoral scholarship at Ghent University. She is author of more than 150 scientific papers of which more than 100 cited in Web of Science, with an h-index of 13.

Currently she is involved in 5 international projects with both industrial and biomedical applications, for identification and control. She was a member of the European Respiratory Society 2006-2008 and she was the first to coin the link between fractional order impedance models for respiratory properties to actual physiology and morphology of the lungs. She is member of several technical committees of IFAC and IEEE, including domains of biomedical engineering applications.