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1 Introduction of Micro-Nanorobotic Manipulation Systems |
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1 | (44) |
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1.1 Background of Micro-Nanorobotic Manipulation Systems |
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2 | (5) |
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1.1.1 Why Micro to Nanotechnology? |
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3 | (1) |
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1.1.2 What Is Micro to Nanotechnology? |
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4 | (1) |
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1.1.3 What Is Micro-Nanorobotic Manipulation Systems? |
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4 | (3) |
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1.2 Strategies and Related Works of Micro-Nanorobotic Manipulation Systems |
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7 | (16) |
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8 | (1) |
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8 | (1) |
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1.2.3 Applicable Fields of Micro-Nanorobotic Manipulation Systems |
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8 | (6) |
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1.2.4 Related Works of Micromanipulations |
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14 | (4) |
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1.2.5 Related Works of Nanomanipulations |
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18 | (5) |
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1.3 Application Fields of Micro-Nanorobotic Manipulation Systems |
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23 | (22) |
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1.3.1 For Micro-Nano Mechatronics |
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23 | (4) |
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1.3.2 For Micro-Nanorobotics |
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27 | (1) |
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1.3.3 For System Cell Engineering |
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28 | (1) |
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1.3.4 For Single Cell Analysis |
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29 | (3) |
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1.3.5 For 3D Cell Assembly |
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32 | (6) |
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38 | (7) |
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2 Physics in Micro-Nano Scale |
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45 | (16) |
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2.1 Scaling Effects in Micro-Nano Scale |
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45 | (1) |
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2.2 Mechanics in Micro-Nano Scale |
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46 | (1) |
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2.2.1 van der Waals Forces |
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46 | (1) |
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2.2.2 Elastic Properties in Micro-Nanometer Scale |
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47 | (1) |
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2.3 Electronics in Micro-Nano Scale |
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47 | (4) |
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2.3.1 Electrostatic Force |
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47 | (1) |
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48 | (1) |
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2.3.3 Electrophoretic Force |
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49 | (1) |
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2.3.4 Field Emission Mechanism |
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49 | (1) |
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2.3.5 Optical Dielectrophoresis |
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50 | (1) |
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2.4 Fluidics in Micro-Nano Scale |
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51 | (2) |
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51 | (1) |
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2.4.2 Diffusion Phenomenon |
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51 | (1) |
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2.4.3 Navier-Stokes Equations |
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51 | (1) |
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52 | (1) |
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52 | (1) |
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53 | (1) |
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2.5 Surface Interaction in Micro-Nano Scale |
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53 | (5) |
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2.5.1 Analysis of Intermolecular and Surface Forces |
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54 | (1) |
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2.5.2 Picking Up by Applying Dielectrophoresis under Surface Forces |
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55 | (1) |
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2.5.3 Adhesion Force of Micro-Nano Fibers |
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56 | (2) |
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2.6 Laser Trapping Mechanism |
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58 | (3) |
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59 | (2) |
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3 Related Technologies on Micro-Nanorobotic Manipulation Systems |
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61 | (46) |
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3.1 Materials and Science in Micro-Nano Scale |
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61 | (12) |
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3.1.1 Carbon Nanomaterials |
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61 | (1) |
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61 | (8) |
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69 | (1) |
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3.1.4 Hydrophilic/Hydrophobic Material |
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69 | (2) |
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3.1.5 Biocompatible Material |
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71 | (2) |
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3.2 Microscopes in Micro-Nano Scale |
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73 | (10) |
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3.2.1 Optical Microscopes |
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73 | (4) |
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3.2.2 Scanning Probe Microscopes |
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77 | (1) |
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3.2.3 Electron Microscope |
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78 | (5) |
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3.3 Fabrication Techniques in Micro-Nano Scale |
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83 | (7) |
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83 | (2) |
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3.3.2 Electron-Beam-Induced Fabrication System |
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85 | (3) |
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3.3.3 Focused Ion Beam System |
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88 | (1) |
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3.3.4 Nano-imprinting System |
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89 | (1) |
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3.3.5 Self-Assembly Techniques |
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90 | (1) |
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3.4 Sensing and Actuation in Micro-Nano Scale |
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90 | (4) |
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3.4.1 Sensing in Micro-Nano Scale |
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90 | (2) |
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3.4.2 Actuation in Micro-Nano Scale |
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92 | (2) |
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3.5 Control Techniques in Micro-Nano Scale |
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94 | (4) |
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3.5.1 Master-Slave Control System for Micro-Nano Manipulation |
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95 | (2) |
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3.5.2 Control of Master-Slave Control System for Laser Manipulation |
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97 | (1) |
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3.6 Assembly Techniques in Micro-Nano Scale |
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98 | (9) |
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3.6.1 2D Assembly Technique in Micro-Nano Scale |
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98 | (1) |
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3.6.2 3D Assembly Technique in Micro-Nano Scale |
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99 | (1) |
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100 | (7) |
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4 Micromanipulation System under Optical Microscope |
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107 | (30) |
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4.1 Biomicromanipulation Methods for On-Chip Cell Experiments |
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107 | (6) |
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4.2 Multiple Trapping by Optical Tweezers |
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113 | (7) |
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4.2.1 Time Shared Scanning (TSS) Laser Trapping System |
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113 | (4) |
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4.2.2 Computer Generated Hologram (CGH) method |
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117 | (3) |
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4.3 Configurations of Micro-Fluidics Chips |
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120 | (2) |
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4.4 Non-contact Manipulation with Micro-tool |
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122 | (7) |
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4.4.1 Roles of Micro-tool for On-Chip Cell Experiment System |
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123 | (2) |
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4.4.2 On-Chip Cell Experiment System with Non-contact Manipulation of Micro-tool |
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125 | (1) |
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4.4.3 Reversible Injection Method of Microtool by Dielectrophoretic Floating of Microtool |
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126 | (3) |
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4.5 Micro-tools for Lasermicromanipulations |
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129 | (8) |
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134 | (3) |
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5 Rotational Speed Control of Single Bacterial Flagellar Motor |
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137 | (26) |
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5.1 Background of Rotational Speed Control of Single Bacterial Flagellar Motor |
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137 | (3) |
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137 | (1) |
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5.1.2 Principal of Flagellar Motor |
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137 | (1) |
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5.1.3 Research Goal of Micro-Nanorobots Using Flagellar Motor |
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138 | (1) |
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5.1.4 Driving Force Generated by Flagellum |
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139 | (1) |
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5.2 Experimental Set-Up for Rotational Speed Control of Single Bacterial Flagellar Motor |
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140 | (8) |
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5.2.1 Switching Discharge between Micro-Nano Dual Pipettes |
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141 | (3) |
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5.2.2 Simultaneous Discharge from Micro-Nano Dual Pipettes |
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144 | (1) |
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5.2.3 Upgrade of Micro-Nano Dual Pipettes System |
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144 | (1) |
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5.2.4 Concept of Simultaneous Discharge |
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145 | (1) |
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5.2.5 Automation of Voltage Control and Synchronization with Video |
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146 | (1) |
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5.2.6 Hardware Configuration |
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146 | (1) |
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5.2.7 Rotational Speed Control of Bacterial Flagellar Motor |
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147 | (1) |
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5.3 Rotational Speed Measurement of Flagellar Motor |
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148 | (7) |
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148 | (1) |
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5.3.2 Experimental Set-Up for Rotational Speed Measurement of Flagellar Motor |
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149 | (1) |
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5.3.3 Experimental Results of Rotational Speed Measurement of Flagellar Motor |
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150 | (3) |
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5.3.4 Discussions of Rotational Speed Measurement of Flagellar Motor |
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153 | (2) |
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5.4 Steady-State Control of Rotational Speed of Flagellar Motor |
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155 | (8) |
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5.4.1 Experimental Set-up for Steady-State Control of Rotational Speed of Flagellar Motor |
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155 | (2) |
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5.4.2 Experimental Results of Steady-State Control of Rotational Speed of Flagellar Motor |
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157 | (1) |
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5.4.3 Estimation of Torque Generated by Flagellar Motor |
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158 | (1) |
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159 | (4) |
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6 Nanomanipulation System under Electron Microscope |
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163 | (34) |
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6.1 Configuration of Nanomanipulation System |
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163 | (1) |
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6.2 Nanorobotic Manipulation System Inside SEM |
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163 | (9) |
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6.2.1 Design of Nanorobotic Manipulation System Inside SEM |
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163 | (2) |
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6.2.2 Link Coordination of Nanorobotic Manipulation System Inside SEM |
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165 | (6) |
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6.2.3 Configuration of Control System of Nanorobotic Manipulation System Inside SEM |
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171 | (1) |
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6.3 Hybrid Nanorobotic Manipulation System Inside SEM/TEM |
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172 | (9) |
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6.4 Nanorobotic Manipulation System Inside E-SEM |
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181 | (4) |
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6.4.1 Design of Nanorobotic Manipulation System Inside E-SEM |
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182 | (1) |
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6.4.2 Link Coordination of Nanorobotic Manipulation System Inside E-SEM |
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183 | (2) |
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185 | (3) |
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6.6 Nano-tool Exchanger System under Hybrid Microscope |
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188 | (2) |
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6.7 Automation of Nanorobotic Manipulation System Inside E-SEM |
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190 | (7) |
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195 | (2) |
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7 Measurement/Manipulation/Assembly of Carbon Nanotubes under FE-SEM/TEM |
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197 | (46) |
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7.1 Application Fields of Nanomanipulation System under FE-SEM/TEM |
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197 | (1) |
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7.2 Mechanical Evaluation of Carbon Nanotubes |
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197 | (4) |
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7.3 Deposition Using Carbon Nanotube Emitters |
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201 | (19) |
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7.4 3D Assembly of Carbon Nanotube |
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220 | (10) |
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7.5 Nano-actuator Using Telescoping Carbon Nanotube |
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230 | (13) |
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237 | (6) |
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8 Biological Cell Manipulation/Measurement/Analysis under E-SEM |
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243 | (84) |
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8.1 Application Fields of Nano-manipulation System under E-SEM |
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243 | (1) |
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8.2 Single Cell Nano-surgery System Using Nano-tools |
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243 | (1) |
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8.3 Observation of Biological Cells by E-SEM |
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243 | (3) |
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8.3.1 Preparing the W303 Wild-Type Yeast Cells for E-SEM Observation |
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244 | (1) |
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8.3.2 Qualitative Evaluation of-Cell Survivability of W303 Cells under E-SEM Observation |
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245 | (1) |
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8.4 Mechanical Property Characterization of Single Cell Using Nanotools |
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246 | (32) |
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8.4.1 Nanoindentation Process |
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246 | (2) |
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8.4.2 Force Measurement Using AFM Cantilever |
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248 | (1) |
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8.4.3 Determination of the Cantilever Deflection via Angular Deflection |
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249 | (3) |
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8.4.4 Calibration of the Spring Constant of the AFM Cantilever |
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252 | (5) |
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8.4.5 Modeling of Single Cell Stiffness |
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257 | (5) |
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8.4.6 Fabrication of Nanoprobe |
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262 | (2) |
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8.4.7 Measurement of Single Cell Stiffness by E-SEM Nanomanipulation |
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264 | (14) |
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8.5 Viscoelastic Measurement of Single Cell Using Sharp, Flat and Bucking Tips Inside E-SEM |
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278 | (13) |
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8.5.1 Modeling for Viscoelastic Measurement of Single Cell |
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280 | (5) |
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8.5.2 Fabrication and Calibration of Nanoprobe for Viscoelastic Measurement of Single Cell |
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285 | (2) |
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8.5.3 Viscoelastic Measurement of Single Cell by E-SEM Nanomanipulation |
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287 | (4) |
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8.6 Single Cell Adhesion Force Measurement Using Nanofork |
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291 | (8) |
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8.6.1 Fabrication and Calibration of Nanoprobe and Line-Patterned Substrate for Viscoelastic Measurement of Single Cell |
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293 | (3) |
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8.6.2 Experimental Result of Adhesion Measurement of Single Cells by Nanofork |
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296 | (3) |
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8.7 Dynamic Single Cell-Cell Adhesion Force Measurement Using Nanopicker |
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299 | (8) |
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8.7.1 Preparation of a Micro Probe |
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301 | (1) |
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8.7.2 Cell Transfer by the Micro Probe |
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302 | (3) |
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8.7.3 Results and Discussion |
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305 | (2) |
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8.8 Electrical Measurement of Single Cell Using Dual Nanoprobe |
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307 | (5) |
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8.8.1 Analysis of the Single Cells Electrical Measurement Using Dual Nanoprobe |
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307 | (2) |
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8.8.2 Fabrication of the Dual Nanoprobe |
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309 | (2) |
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8.8.3 Electrical Measurement of Dead Cells under HV Mode |
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311 | (1) |
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8.9 Automation System of Single Cell Analysis Using Nanotools |
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312 | (4) |
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313 | (2) |
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315 | (1) |
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8.10 Local Measurement and Injection to C. elegans Using Nanotools |
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316 | (11) |
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8.10.1 Direct Observation of C. elegans by E-SEM |
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316 | (1) |
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8.10.2 Viability Test of C. elegance though E-SEM |
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317 | (1) |
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8.10.3 Local Stiffness Evaluation of C. elegans Using Nanoprobe Inside E-SEM |
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318 | (2) |
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8.10.4 Local Injection into C. elegans Using Nanoprobe Inside E-SEM |
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320 | (1) |
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321 | (6) |
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327 | (4) |
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327 | (1) |
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328 | (3) |
Subject Index |
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331 | |