Rapley (University of Hertfordshire, UK) and Harbon, a consultant in enzyme technology, present an overview of recent developments in the field of molecular-based diagnostics of disease markers. Following a historical overview of pharmacogenetics and pharmacogenomics, experts in the field illustrate the latest techniques with examples from their own laboratories and describe approaches to the identification of new target compounds. The book will be useful to students in courses on molecular medicine, biotechnology, and molecular biology, and will also be of use as a reference for researchers in the biotechnology and pharmaceutical industries. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
This advanced level textbook provides a comprehensive overview of recent developments in the area of molecular based diagnostics (including nucleic acids, biosensors and immunoessays) of disease markers. It also covers the impact of techniques such as in vitro nucleic acid amplifications (e.g. PCR) and other amplification methods, as well as gene and biochip production and automated techniques such as fluorescent sequencing.
The book discusses key concepts where new and merging areas, including pharmacogenomics, proteomics and functional genomics, are being researched and developed. In addition, examples are given where this new area of bioscience has or may be successfully applied.