The field of nutrigenomics seeks to understand the variability of the individual's response to food and the underlying mechanisms whereby foods exert their health-promoting properties. Focusing on Asian societies, Tai (endocrinology, Singapore General Hospital) and Gillies (DuPont Haskell Laboratory for Health and Environmental Sciences) explore the role of ethnic diversity, dietary patterns, and genetic adaptation in determining individual nutrient requirements throughout the life cycle. The book begins with a review of concepts and methods in the field, in areas such as nutrition and genome health, proteomics, diet and genomic stability, and ethical and social implications. This is followed by research on nutrigenomics and health topics, including the genetics of lipoprotein metabolism and heart disease, and gene expression in low-glycemic index diets. Applications to the food industry are also discussed. Material originated at a December 2005 meeting hosted by the International Life Sciences Institute and held in Singapore. The audience for the book includes scientists, and medical, nutrition, and other health professionals. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
Preface: Tai, E.S.; Gillies, P.J.; Concepts and Methods in
Nutrigenomics; Nutrition in the 'Omics' Era: Milner, J.A.; Nutrigenetics:
El-Sohemy, A.; Epigenomics and Nutrition: Cobiac, L.; Early Nutrition: Impact
on Epigenetics: Mathers, J.C.; Nutrition and Genome Health: Fenech, M.;
Nutrition: Ethics and Social Implications: Slamet-Loedin, I.H.; Jenie, U.A.;
Proteomics: Thongboonkerd, V.; Diet and Genomic Stability: Young, G.P.;
High-Throughput Genotyping: Lee, J.-E.; Nutrigenomics and Health;
Nutrient-Gene Interactions in Lipoprotein Metabolism - An Overview: Ordovas,
J.M.; Corella, D.; Kaput, J.; The Genetics of Lipoprotein Metabolism and
Heart Disease: Tai, E.S.; Gene-Environment Interactions and the Diabetes
Epidemic in India: Mohan, V.; Sudha, V.; Radhika, G.; Radha, V.; Rema, M.;
Deepa, R.; Gene Expression in Low Glycemic Index Diet - Impact on Metabolic
Control: Takeda, E.; Arai, H.; Muto, K.; Matsuo, K.; Sakuma, M.; Fukaya, M.;
Yamanaka-Okumura, H.; Yamamoto, H.; Taketani, Y.; Genetic Polymorphisms in
Folate-Metabolizing Enzymes and Risk of Gastroesophageal Cancers: A Potential
Nutrient-Gene Interaction in Cancer Development: Lin, D.; Li, H.; Tan, W.;
Miao, X.; Wang, L.; Dietary Quercetin Inhibits Proliferation of Lung
Carcinoma Cells: Hung, H.; Osteoporosis: The Role of Genetics and the
Environment: Ongphiphadhanakul, B.; Application of Nutrigenomics in Eye
Health: Delcourt, C.; Nutrigenomics - Applications to the Food Industry;
Nutrigenomics of Taste - Impact on Food Preferences and Food Production:
El-Sohemy, A.; Stewart, L.; Khataan, N.; Fontaine-Bisson, B.; Kwong, P.;
Ozsungur, S.; Cornelis, M.C.; Prospects for Improving the Nutritional Quality
of Dairy Meat Products: Coffey, S.G.; Functionality of Probiotics - Potential
for Product Development: Dekker, J.; Collett, M.; Prasad, J.; Gopal, P.;
Conclusion; Developing the Promise of Nutrigenomics through Complete Science
and International Collaborations: Kaput, J.; Executive Summary; ILSI's First
International Conference on Nutrigenomics: Opportunities in Asia: Florentino,
R.F.
