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Understanding Coronavirus [Pehme köide]

(Columbia University, New York)
  • Formaat: Paperback / softback, 120 pages, kõrgus x laius x paksus: 125x180x10 mm, kaal: 130 g, Worked examples or Exercises
  • Sari: Understanding Life
  • Ilmumisaeg: 16-Jun-2020
  • Kirjastus: Cambridge University Press
  • ISBN-10: 1108826717
  • ISBN-13: 9781108826716
  • Formaat: Paperback / softback, 120 pages, kõrgus x laius x paksus: 125x180x10 mm, kaal: 130 g, Worked examples or Exercises
  • Sari: Understanding Life
  • Ilmumisaeg: 16-Jun-2020
  • Kirjastus: Cambridge University Press
  • ISBN-10: 1108826717
  • ISBN-13: 9781108826716
Since the identification of the first cases of the coronavirus in December 2019 in Wuhan, China, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', officially named SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the newly emerging virus and the inconsistent public health measures across different countries, have all served to increase the level of anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? What can we do to stop its spread? Written by a leading expert, this concise and accessible introduction provides answers to the most common questions surrounding coronavirus for a general audience.

Why is the information available about the coronavirus/COVID-19 so confusing? Written by a leading researcher, Understanding Coronavirus is a concise and accessible introduction to all the science and facts you need to understand how the virus works, how it spreads and how it compares to other respiratory viruses.

Arvustused

'With all the technology and medical knowledge of the 21st century a pandemic virus has defeated us. This book tells us why and how that could happen and what we can do about it. And as a bonus we get a comparison with the 1918 pandemic Flu. All this wrapped up in a clear, understandable and interesting way. We learn what is happening to us now and how to better prepare for the future.' Arnold J. Levine, Institute for Advanced Study, Princeton, New Jersey 'An extremely concise and important book that everyone should read to understand the dynamics of the COVID-19 pandemic.' Siddhartha Mukherjee, Columbia University, New York, and author of The Gene and The Emperor of All Maladies 'Raul Rabadan has written an essential book for the first pandemic of the 21st century, COVID19 caused by SARS-CoV-2. It's a wonderfully concise and accessible explanation of everything you want to know about the virus, the disease, and the outbreak. If you want to learn what is a coronavirus, how the outbreak started, what are the therapeutic options, and much more, I highly recommend this book. Professor Rabadan explains viruses in a way that is accessible to all.' Vincent Racaniello, Columbia University, New York 'A much-needed primer that offers basic information What Understanding Coronavirus does very well is clarify virology and epidemiology basics. Asking how quickly the virus spreads means explaining the basic reproduction number R0 and concepts such as 'flattening the curve' and herd immunity that everyone has been confronted with. It explains the symptoms, the typical course of the disease, how deadly it is, and that, yes, children and young adults get infected too, but their symptoms are usually less severe Understanding Coronavirus overall provides a lot of relevant information in a very readable and concise format. And at this price, you cannot really go wrong.' Leon Vlieger, Natural History Book Service 'A clear scientific guide to COVID-19 ... (it) illuminates coronavirus science not only with clear writing but also with good graphics and illustrations.' Clive Cookson, Financial Times 'This small book could be required reading for many politicians and journalists ' Tilli Tansey, Nature

Muu info

Why is information about the coronavirus/COVID-19 so confusing? Grasp the key facts in this concise, accessible and authoritative book.
Foreword by Series Editor xi
Preface xiii
List of Abbreviations
xvi
1 Introduction
1(6)
2 How Is the Coronavirus Spreading?
7(14)
How Long Does It Take to Have Symptoms?
8(1)
How Many People Will the Virus Infect?
9(1)
How Quickly Does the Virus Spread in the Population?
10(2)
How Many People Will Die from the Disease?
12(2)
How Does the Severity of Diseases Vary?
14(2)
What Is "Flattening the Curve" and Why Is It Important?
16(2)
What Is Herd Immunity?
18(3)
3 What Is a Coronavirus?
21(12)
What Is a Virus?
22(1)
What Are the Coronaviruses?
23(2)
Where Are Coronaviruses Found?
25(1)
What Is the Structure of a Coronavirus?
26(3)
How Does the Coronavirus Enter Cells and Replicate?
29(2)
How Are the New Coronaviruses Released from the Infected Cell?
31(2)
4 Now Is the Coronavirus Changing?
33(12)
What Is a Mutation?
34(3)
What Is a Recombination?
37(3)
How Do We Track Back the Origin of SARS-CoV-2?
40(5)
5 How Did the COVID-19 Outbreak Start and Evolve?
45(18)
What Is SARS-CoV-2 and What Is COVID-19?
45(1)
Where Was SARS-CoV-2 First Reported?
46(3)
Where Is It Coming From?
49(2)
How Is It Related to Other Coronaviruses?
51(2)
How Does It Enter Human Cells?
53(2)
How Does It Spread?
55(1)
What Are the Clinical Characteristics?
56(2)
How Deadly Is It?
58(1)
Are Age, Sex, and Other Diseases Affecting Death Rates?
59(1)
Does the Virus Infect Children?
59(3)
How Fast Is the Virus Spreading?
62(1)
Is the Coronavirus Diversifying?
62(1)
6 How Does the COVID-19 Outbreak Compare to the SARS Outbreak in 2003?
63(10)
How Did the SARS Outbreak Start?
64(2)
Where Was the SARS Virus Coming From?
66(2)
Were There Any Super-Spreaders?
68(1)
What Are the Clinical Characteristics of SARS and How Does It Compare to COVID-19?
69(1)
How Different Are SARS-CoV and SARS-CoV-2 and Their Diseases?
70(1)
How Did SARS Disappear?
71(1)
How Was SARS-CoV-2 Able to Propagate While SARS-CoV Was Controlled?
71(2)
7 How Does the COVID-19 Outbreak Compare to Seasonal and Pandemic Influenza?
73(12)
Is the Influenza Virus Related to Coronavirus?
74(1)
What Is Pandemic Influenza?
75(5)
What Is Seasonal Influenza?
80(2)
How Does Influenza Transmit and Cause Disease?
82(1)
How Does Influenza Virus and Illness Compare with SARS-CoV-2 and COVID-19?
82(1)
What Did We Learn from the Public Health Measures Taken in the 1918 Pandemic Flu?
83(2)
8 Are There Therapeutic Options?
85(6)
How Is the Virus Diagnosed?
85(3)
How Are the Infections Treated?
88(1)
Are There Any Drugs Used to Treat Coronavirus Infections?
88(2)
Are There Vaccines for Coronaviruses?
90(1)
Conclusions 91(4)
Summary of Common Misunderstandings 95(3)
Updates at Press 98(2)
Suggested Further Reading 100(9)
Figure and Quotation Credits 109(3)
Index 112
Raul Rabadan is a Professor in the Department of Systems Biology and Biomedical Informatics, as well as the director of the Program for Mathematical Genomics, at Columbia University. From 2001 to 2003, Dr. Rabadan was a fellow at the Theoretical Physics Division at CERN, the European Organization for Nuclear Research, in Geneva, Switzerland. In 2003 he joined the School of Natural Sciences at the Institute for Advanced Study in Princeton, New Jersey. He has been named one of Popular Science's Brilliant 10 (2010), a Stewart Trust Fellow (2013), and he received the Harold and Golden Lamport (2014), Diz Pintado (2018) and Phillip Sharp (2018) awards. Dr. Rabadan's current interest focuses on uncovering patterns of evolution in biological systems in particular, RNA viruses and cancer.