Muutke küpsiste eelistusi

Understanding the Gut Microbiota [Kõva köide]

  • Formaat: Hardback, 184 pages, kõrgus x laius x paksus: 244x175x15 mm, kaal: 476 g
  • Ilmumisaeg: 10-Feb-2017
  • Kirjastus: John Wiley & Sons Inc
  • ISBN-10: 1118801423
  • ISBN-13: 9781118801420
  • Formaat: Hardback, 184 pages, kõrgus x laius x paksus: 244x175x15 mm, kaal: 476 g
  • Ilmumisaeg: 10-Feb-2017
  • Kirjastus: John Wiley & Sons Inc
  • ISBN-10: 1118801423
  • ISBN-13: 9781118801420

This book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans. Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective of knowledge about this high profile and fast-moving topic. Building on general ecological principles, the book aims to help the reader to understand how the microbiota is formed, how it works, and what the consequences are to humans.

Understanding the Gut Microbiota focuses on conceptual progress made from studies of the human bowel microbiota. Where appropriate, it draws on knowledge obtained from other animal species to provide conceptual enlightenment, but this is essentially a book about humans and their bowel microbes. Particular research approaches are recommended to fill knowledge gaps so that fundamental ecological theory and information about the microbiota can be translated into benefits for human health. The relationship between food for humans and resulting food for bowel bacteria emerges as an important topic for consideration.

This concise scholarly treatise of the microbiota of the human bowel will be of great interest and use as a text and reference work for professionals, teachers and students across a wide range of disciplines, including the health sciences, general biology, and food science and technology. The provision of handy ‘explanation of terms’ means that those with a general interest in science can also read the book with enjoyment.

Preface vii
Acknowledgements ix
1 Introduction
1(6)
References
4(3)
2 Prime Facts
7(12)
Summary
14(1)
Explanation of Terms
15(1)
References
16(3)
3 A Sense of Community
19(20)
Summary
33(1)
Explanation of Terms
33(2)
References
35(4)
4 Assembling Communities
39(24)
Summary
55(1)
Explanation of Terms
55(1)
References
56(7)
5 Bowel Society
63(8)
References
69(2)
6 Chemostat Bowel
71(16)
Summary
82(1)
Explanation of Terms
82(1)
References
83(4)
7 Revealing Secret Lives
87(18)
Summary
98(1)
Explanation of terms
98(3)
References
101(4)
8 Remembrance of Microbes Past
105(10)
Summary
111(1)
References
112(3)
9 Out of Tune: Dysbiosis
115(24)
Summary
130(1)
Explanation of Terms
130(2)
References
132(7)
10 We may be Lost, but we're Making Good Time
139(20)
Particularly Important Considerations
143(2)
Running Out of Fuel?
145(1)
The End of the Journey
146(1)
References
146(3)
Addendum: A Brief Summary of Technological Aspects of -omics
149(1)
General Features of Nucleic Acid-based Technology
149(1)
Older Electrophoretic Methods for Screening Microbiota Compositions
150(1)
Fluorescent Probes (FISH/FC)
151(1)
Measuring the Abundance of Bacterial Groups by qPCR
152(1)
Using DNA Chips to Screen Microbiota Compositions
153(1)
Detailed Phylogenetic Analysis
154(1)
Metagenomics: Determining the Functional Capacity of Microbiotas
155(1)
Metatranscriptomics: Microbiota Biochemical Pathways in Action
156(1)
Metaproteomics
157(1)
Metabolomics
157(1)
Summary
158(1)
References 159(4)
Index 163
Professor Gerald W. Tannock is based at the University of Otago and was awarded a Professorial Chair in 1996. He was awarded a Royal Society of New Zealand Silver Medal in 2000 for his contributions to science and technology and was elected a Fellow of the American Academy of Microbiology in 2002. Professor Tannock's research concerns the communities of bacteria that inhabit the gastrointestinal tract of animals. Research projects include the microbiology of inflammatory bowel diseases, the use of a unique colony of Lactobacillus-free mice in investigating the molecular foundations of gut autochthony using lactobacilli as model bacteria, engineering bowel communities by dietary manipulation, and the impact of bifidobacterial species on the activation of human dendritic cells with respect to atopic diseases. Professor Tannock's expertise has added an important microbiological facet to national and international, multi-disciplinary clinical studies in recent years.