Muutke küpsiste eelistusi

Aging: Exploring a Complex Phenomenon [Kõva köide]

Edited by (Nottingham Trent University, United Kingdom)
  • Formaat: Hardback, 658 pages, kõrgus x laius: 254x178 mm, kaal: 1960 g, 29 Tables, black and white; 35 Illustrations, color; 38 Illustrations, black and white
  • Ilmumisaeg: 25-Oct-2017
  • Kirjastus: CRC Press
  • ISBN-10: 1138196975
  • ISBN-13: 9781138196971
Teised raamatud teemal:
  • Formaat: Hardback, 658 pages, kõrgus x laius: 254x178 mm, kaal: 1960 g, 29 Tables, black and white; 35 Illustrations, color; 38 Illustrations, black and white
  • Ilmumisaeg: 25-Oct-2017
  • Kirjastus: CRC Press
  • ISBN-10: 1138196975
  • ISBN-13: 9781138196971
Teised raamatud teemal:

This book is a detailed and comprehensive synthesis of the scientific study of aging. Dozens of contributions from leading scholars review various theories of aging, and molecular, cellular, biochemical and microbial aspects of aging, among just a few of the topics included. Authoritative, wide ranging and thorough, this book will act as a source for experimental design, a comprehensive description of age related diseases, and provide information of the latest molecular theories underlying their causes. Additionally, it will target industries involved in developing anti-aging drugs, post-graduate medical students, and university libraries.

Preface xi
One World, One Humanity xv
Acknowledgments xvii
Editor xix
Contributors xxi
SECTION I Introduction to Aging
Chapter 1 A Synopsis on Aging
3(20)
Joao Pinto da Costa
Chapter 2 Understanding Aging after Darwin
23(20)
Michael A. Singer
SECTION II Aging Hypothesis
Chapter 3 Evolutionary Theories of Aging: A Systemic and Mechanistic Perspective
43(30)
Quentin Vanhaelen
Chapter 4 The Indispensable Soma Hypothesis in Aging
73(18)
Marios Kyriazis
Chapter 5 Programmed Aging Paradigm and Aging of Perennial Neurons
91(26)
Giacinto Libertini
Chapter 6 The Genetic Program of Aging
117(18)
Xiufang Wang
Huanling Zhang
Libo Su
Zhanjun Lv
Chapter 7 The Origins of Aging: Multicellularity, Speciation, and Ecosystems
135(26)
Michael A. Singer
Chapter 8 Human Culture: Urbanization and Human Aging
161(14)
Michael A. Singer
Chapter 9 Aging Epigenetics: Accumulation of Errors and More
175(34)
Vastly V. Ashapkin
Lyudmila I. Kutueva
Boris F. Vanyushin
SECTION III Diseases Associated with Aging and Treatment
Chapter 10 The Premature Aging Characteristics of RecQ Helicases
209(22)
Christ Ordookhanian
Taylor N. Dennis
J. Jefferson
P. Perry
Chapter 11 Cockayne Syndrome and the Aging Process
231(6)
Maria de la Luz Arenas-Sordo
Chapter 12 Cancer: The Price for Longevity
237(10)
Karel Smetana Jr.
Barbora Dvorankova
Lukas Lacina
Pavol Szabo
Betr Broz
Aleksi Sedo
Chapter 13 Nodular Thyroid Disease with Aging
247(12)
Enke Baldini
Salvatore Sorrenti
Antonio Catania
Francesco Tartaglia
Daniele Pironi
Massimo Vergine
Massimo Monti
Angelo Filippini
Salvatore Ulisse
Chapter 14 HIV and Aging: A Multifaceted Relationship
259(12)
Edward J. Wing
Chapter 15 Maturation, Barrier Function, Aging, and Breakdown of the Blood--Brain Barrier
271(34)
Elizabeth de Lange
Agnes Bajza
Peter Imre
Attila Csorba
Laszlo Denes
Franciska Erdo
Chapter 16 Senescent Cells as Drivers of Age-Related Diseases
305(30)
Cielo Mae D. Marquez
Michael C. Velarde
Chapter 17 Osteoimmunology in Aging
335(16)
Lia Ginaldi
Daniela Di Silvestre
Maria Maddalena Sirufo
Massimo De Martinis
Chapter 18 Manipulating Aging to Treat Age-Related Disease
351(6)
V. Mallikarjun
J. Swift
Chapter 19 Therapeutic Options to Enhance Poststroke Recovery in Aged Humans
357(26)
Aurel Popa-Wagner
Dumbrava Danut
Roxana Surugiu
Eugen Petcu
Daniela-Gabriela Glavan
Denissa-Greta Olaru
Raluca Sandu Elena
SECTION IV Mechanisms of Aging
Chapter 20 Increase in Mitochondrial DNA Fragments inside Nuclear DNA during the Lifetime of an Individual as a Mechanism of Aging
383(12)
Gustavo Barja
Chapter 21 Mitochondrial Oxidative Stress in Aging and Healthspan
395(28)
Dao-Fu Dai
Chapter 22 Immunology of Aging and Cancer Development
423(14)
T. Fulop
J. M. Witkowski
G. Dupuis
A. Le Page
A. Larbi
G. Pawelec
Chapter 23 Oxidation of Ion Channels in the Aging Process
437(18)
Federico Sesti
Chapter 24 Lipid Raft Alteration and Functional Impairment in Aged Neuronal Membranes
455(20)
Julie Colin
Lynn Gregory-Pauron
Frances T. Yen
Thierry Oster
Catherine Malaplate-Armand
Chapter 25 Autophagy: The Way to Death or Immortality? Activators and Inhibitors of Autophagy as Possible Modulators of the Aging Process
475(14)
Galina V. Morgunova
Alexander A. Klebanov
Alexander N. Khokhlov
SECTION V Treatments in Aging
Chapter 26 Aging: Grounds and Determents
489(10)
Sreeja Lakshmi
Preetham Elumalai
Chapter 27 Skin Aging Clock and Its Resetting by Light-Emitting Diode Low-Level Light Therapy
499(18)
R. Glen Calderhead
SECTION VI Healthy and Successful Aging
Chapter 28 Social Structure and Healthy Aging: Case Studies
517(8)
Jong In Kim
Gukbin Kim
Chapter 29 Successful Aging: Role of Cognition, Personality, and Whole-Person Wellness
525(18)
Peter Martin
Leonard W. Poon
Kyuho Lee
Yousun Baek
Jennifer A. Margrett
Chapter 30 Physical Activity in Prevention of Glucocorticoid Myopathy and Sarcopenia in Aging
543(16)
Teet Seene
Priit Kaasik
Chapter 31 Reductionism versus Systems Thinking in Aging Research
559(18)
Marios Kyriazis
SECTION VII Anti-Aging Drugs
Chapter 32 Anti-Aging Drug Discovery in Experimental Gerontological Studies: From Organism to Cell and Back
577(22)
Alexander N. Khokhlov
Alexander A. Klebanov
Galina V. Morgunova
SECTION VIII Aging in Caenorhabditis elegans
Chapter 33 Caenorhabditis elegans Aging Is Associated with a Decline in Proteostasis
599(18)
Elise A. Kikis
SECTION IX Hibernation and Aging
Chapter 34 Hibernation and Aging: Molecular Mechanisms of Mammalian Hypometabolism and Its Links to Longevity
617(20)
Cheng-Wei Wu
Kenneth B. Storey
SECTION X Mathematical Modeling of Aging
Chapter 35 The Role of Mathematical Modeling in Understanding Aging
637(16)
Mark Mc Auley
Amy Morgan
Kathleen Mooney
Index 653
Shamim I. Ahmad received his PhD from Leicester University and has been Lecturer at Nottingham Trent University where he the British Asian Award for "Excellence in Education." He has authored or edited eleven books and dozens of peer reviewed research papers. His research interests are in the field of DNA damage and repair and associated diseases, molecular mechanisms of Fanconi anemia, role of reactive oxygen species (ROS) in health and diseases, skin cancer by sunlight, Anti-AIDS drug development, development of new procedures for treatment of cancer, viral and bacterial infections.