A comprehensive reference, this book explores both pathogenic and clinical aspects of alcoholic liver disease (ALD). The authors provide an in-depth review of the major mechanisms thought to contribute to ALD and, where possible, relate the basic science to pathogenesis and potential treatment modalities. They cover clinical aspects, diagnosis and patient management, histopathology, ethanol metabolism and its consequences, mechanisms in the pathogenesis of ALD, interaction of alcohol with viral hepatitis, and more. The book is an essential resource for basic scientists and clinicians and anyone investigating the effects of alcohol and liver pathologies.
Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alcoholic liver disease. Providing broader coverage of the subject than any available monograph, the editors and their panel of experts relate basic science to pathogenesis and treatment modalities and explore future developments.
Coverage includes:
Histopathology-fatty liver, alcoholic hepatitis, and cirrhosis
Ethanol metabolism and its consequences
Mechanisms in the pathogenesis of ALD, including genetics, immunology, and insulin-like growth factors
Extrahepatic effects of ALD and the role of alcohol in potentiating liver damage due to other etiologies
Interaction of alcohol with viral hepatitis
Epidemiology, diagnosis, and treatment
Management strategies, including transplantation
The vast amount of knowledge and expertise gathered in this book make it an unparalleled resource.