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E-raamat: Ethanol and the Liver: Mechanisms and Management

(University of Arizona, Tucson, USA),
  • Formaat: 718 pages
  • Ilmumisaeg: 30-May-2002
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781420024272
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  • Formaat: 718 pages
  • Ilmumisaeg: 30-May-2002
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781420024272
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Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alcoholic liver disease. Providing broader coverage of the subject than any available monograph, the editors and their panel of experts relate basic science to pathogenesis and treatment modalities and explore future developments.

Coverage includes:
  • Histopathology-fatty liver, alcoholic hepatitis, and cirrhosis
  • Ethanol metabolism and its consequences
  • Mechanisms in the pathogenesis of ALD, including genetics, immunology, and insulin-like growth factors
  • Extrahepatic effects of ALD and the role of alcohol in potentiating liver damage due to other etiologies
  • Interaction of alcohol with viral hepatitis
  • Epidemiology, diagnosis, and treatment
  • Management strategies, including transplantation

    The vast amount of knowledge and expertise gathered in this book make it an unparalleled resource.
  • Foreword viii
    Preface ix
    List of abbreviations
    xi
    List of contributors
    xvii
    List of color plates
    xx
    Biographies xxii
    PART I Specific lesions 1(92)
    Alcoholic fatty liver
    3(18)
    Andrew J. Bathgate
    Kenneth J. Simpson
    Alcoholic hepatitis
    21(39)
    H. Denk
    K. Zatloukal
    C. Stumptner
    Fibrosis in alcoholic cirrhosis
    60(33)
    Samuel W. French
    PART II Direct and indirect consequences of alcohol metabolism 93(58)
    Genetics of ethanol metabolism and alcoholic liver disease
    95(35)
    Paul Y. Kwo
    David W. Grabb
    Acetaldehyde adducts: role in ethanol-induced liver disease
    130(21)
    John Koskinas
    PART III Mechanisms of damage 151(236)
    Free radicals and alcohol-induced liver injury
    153(38)
    Emanuele Albano
    Ethanol and the hepatic microcirculation
    191(15)
    Robert S. McCuskey
    Cytokines and alcohol liver disease
    206(14)
    F. Javier Laso
    J. Ignacio Madruga
    Alberto Orfao
    Adhesion molecules and chemokines in alcoholic liver disease
    220(24)
    Neil C. Fisher
    David H. Adams
    Role of endotoxin and Kupffer cells as triggers of hypoxia-reoxygenation in alcoholic liver injury
    244(21)
    R.G. Thurman
    B.U. Bradford
    K.T. Knecht
    Y. Iimuro
    G.E. Arteel
    M. Yin
    H.D. Connor
    C. Rivera
    J.A. Raleigh
    M.v. Frankenberg
    Y. Adachi
    D.T. Forman
    D. Brenner
    M. Kadiiska
    R.P. Mason
    Ethanol and protein turnover
    265(32)
    Elena Volpi
    Insulin-like growth factors: clinical and experimental
    297(22)
    Anthony J. Donaghy
    Cellular mechanisms of liver regeneration and the effect of alcohol
    319(24)
    Martin Phillips
    Elika Kashef
    Robin Hughes
    Alcohol and hepatocellular carcinoma
    343(15)
    Stephen D. Ryder
    Animal models of ethanol-induced liver damage
    358(29)
    Harri A. Jarvelainen
    Kai O. Lindros
    PART IV Epidemiology and diagnosis 387(64)
    Epidemiology and comparative incidence of alcohol-induced liver disease
    389(22)
    John B. Saunders
    Benedict M. Devereaux
    Serum diagnosis of alcoholic liver disease and markers of ethanol intake
    411(40)
    Onni Niemela
    PART V Extrahepatic effects 451(82)
    Extrahepatic effects of alcohol: an overview
    453(19)
    Helen L. Reeves
    Christopher P. Day
    Endocrine system
    472(23)
    Christian Gluud
    Cardiomyopathy and skeletal muscle myopathy
    495(17)
    Alvaro Urbano-Marquez
    Joaquim Fernandez-Sola
    Ramon Estruch
    Cerebral consequences of alcoholic liver disease
    512(21)
    Roger F. Butterworth
    PART VI Management 533(149)
    General management of alcoholic liver disease
    535(33)
    Martin Phillips
    John O. Grady
    The role of the psychiatrist in the treatment of alcoholic liver disease
    568(24)
    Jose Martinez-Raga
    E. Jane Marshall
    Pharmacological treatment for alcoholic hepatitis and cirrhosis: present practice and future strategies
    592(22)
    Philippe Mathurin
    Thierry Poynard
    Nutritional support in alcoholic liver disease: practical management and future strategies
    614(24)
    Angela Madden
    Alcohol and viral hepatitis: interactions and management
    638(16)
    Albert Pares
    Joan Caballeria
    Liver transplantation in alcoholic liver disease
    654(28)
    Stephen P. Pereira
    Roger Williams
    Index 682


    Sherman, David; Watson, Ronald Ross