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E-book: Combating Antimicrobial Resistance: A One Health Approach to a Global Threat: Proceedings of a Workshop

  • Format: 172 pages
  • Pub. Date: 08-Dec-2017
  • Publisher: National Academies Press
  • Language: eng
  • ISBN-13: 9780309466554
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  • Format: 172 pages
  • Pub. Date: 08-Dec-2017
  • Publisher: National Academies Press
  • Language: eng
  • ISBN-13: 9780309466554
Other books in subject:

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As of 2017, the emergence and spread of antimicrobial resistance continues unabated around the world, leaving devastating health and economic outcomes in its wake. Those consequences will multiply if collaborative global action is not taken to address the spread of resistance. Major drivers of antimicrobial resistance in humans have been accelerated by inappropriate antimicrobial prescribing in health care practices; the inappropriate use of antimicrobials in livestock; and the promulgation of antibiotic resistance genes in the environment.





To explore the issue of antimicrobial resistance, the Forum of Microbial Threats planned a public workshop. Participants explored issues of antimicrobial resistance through the lens of One Health, which is a collaborative approach of multiple disciplines - working locally, nationally, and globally - for strengthening systems to counter infectious diseases and related issues that threaten human, animal, and environmental health, with an end point of improving global health and achieving gains in development. They also discussed immediate and short-term actions and research needs that will have the greatest effect on reducing antimicrobial resistance, while taking into account the complexities of bridging different sectors and disciplines to address this global threat. This publication summarizes the presentations and discussions from the workshop.

Table of Contents



Front Matter 1 Introduction 2 The Global Momentum to Counter Antimicrobial Resistance 3 Microbial and Genetic Movements Across the One Health Domains 4 Applying Social and Behavioral Sciences to Combating Antimicrobial Resistance 5 Research and Development Actions for Reducing the Need for Antimicrobials 6 Strengthening Partnerships and International Cooperation 7 Moving from Knowledge to Action - Participants' Perspectives References Appendix A: Statement of Task Appendix B: Workshop Agenda Appendix C: Biographical Sketches of Workshop Speakers and Moderators
Acronyms and Abbreviations xvii
1 Introduction
1(4)
Workshop Objectives
2(1)
Organization of the Proceedings of a Workshop
3(2)
2 The Global Momentum to Counter Antimicrobial Resistance
5(8)
Moving from Knowledge to Action
5(3)
Devising and Prioritizing a Strategy for Immediate Action and Implementation
8(5)
3 Microbial and Genetic Movements Across the One Health Domains
13(26)
Strengthening the Knowledge and Evidence Base
14(9)
Discussion
23(1)
Antimicrobials in the Environment
24(12)
Discussion
36(3)
4 Applying Social and Behavioral Sciences to Combating Antimicrobial Resistance
39(30)
Reducing Antimicrobial Use: Stewardship Programs, Incentives, and Policy
40(11)
Discussion
51(2)
Achieving Desired Behavior Change Through Prevention Measures and Education
53(12)
Discussion
65(4)
5 Research and Development Actions For Reducing the Need For Antimicrobials
69(20)
Scientific Advances and Promising Research to Reduce the Need for Antimicrobials from a Human and an Animal Health Perspective
70(5)
Vaccination to Reduce the Burden of Antimicrobial Resistance
75(3)
Research and Development Actions in Diagnostics
78(2)
Economic Strategies for Accelerating Research and Development for New Antimicrobials
80(5)
Discussion
85(4)
6 Strengthening Partnerships and International Cooperation
89(18)
Implementation of the World Health Organization's Global Action Plan on Antimicrobial Resistance at the Country Level
90(2)
Immediate Strategies to Develop or Refine Partnerships
92(8)
The Role of Partnerships in Addressing Antimicrobial Resistance
100(3)
Discussion
103(4)
7 Moving From Knowledge to Action---Participants' Perspectives
107(16)
Suggested Actions to Improve Surveillance
108(1)
Suggested Actions to Improve Stewardship, Infection Prevention, and Behavior Modification
109(1)
Suggested Actions to Improve Basic and Applied Research and Development
109(1)
Suggested Actions to Improve Global Policy and Coordination
110(1)
Synthesis and General Discussion
111(4)
References
115(8)
APPENDIXES
A Statement of Task
123(2)
B Workshop Agenda
125(6)
C Biographical Sketches of Workshop Speakers and Moderators
131