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E-book: Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies

Edited by (Université de Nantes, France), Edited by (Lunds Universitet, Sweden)
  • Format: EPUB+DRM
  • Pub. Date: 25-Jan-2018
  • Publisher: Cambridge University Press
  • Language: eng
  • ISBN-13: 9781108547734
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  • Format: EPUB+DRM
  • Pub. Date: 25-Jan-2018
  • Publisher: Cambridge University Press
  • Language: eng
  • ISBN-13: 9781108547734
Other books in subject:

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Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.

Master the techniques of flow cytometry in diagnosing complex hematological malignancies. Practical and current, this manual presents information from the World Health Organization, including instrument settings and panel construction. This resource supports all users in recognizing hematological abnormalities.

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This practical manual offers an active understanding of how to implement flow-cytometry when facing complex, haematological diseases.
List of Contributors
vii
Preface ix
List of Abbreviations
xi
1 Flow Cytometry in Clinical Haematopathology: Basic Principles and Data Analysis of Multiparameter Data Sets
1(13)
Francis Lacombe
Marie-Christine Bene
2 Antigens
14(22)
Marie-Christine Bene
Anna Porwit
3 Flow Cytometry of Normal Blood, Bone Marrow and Lymphatic Tissue
36(25)
Anna Porwit
Marie-Christine Bene
4 Reactive Conditions and Other Diseases Where Flow Cytometric Findings May Mimic Haematological Malignancies
61(14)
Wolfgang Kern
Marie-Christine Bene
Anna Porwit
5 Examples of Immunophenotypic Features in Various Categories of Acute Leukaemia
75(14)
Marie-Christine Bene
Anna Porwit
6 Acute Lymphoid Leukaemias (AIIl) and Minimal Residual Disease in All
89(16)
Giuseppe Basso
Barbara Buldini
Andrea Zangrando
7 Immunophenotyping of Mature B-Cell Lymphomas
105(23)
Olof Axler
Anna Porwit
8 Plasma Cell Myeloma and Related Disorders
128(12)
Ruth M. de Tute
Andrew C. Rawstron
Roger G. Owen
9 Mature T-Cell Neoplasms and Natural Killer-Cell Malignancies
140(21)
Anne Tierens
10 Flow Cytometric Diagnosis of Hodgkin's Lymphoma in Lymph Nodes
161(10)
Lori Soma
Brent L. Wood
Jonathan R. Fromm
11 Minimal Residual Disease in Acute Myeloid Leukaemia
171(20)
Gerrit J. Schuurhuis
Angele Kelder
Gert J. Ossenkoppele
Jacqueline Cloos
Wendelien Zeijlemaker
12 Ambiguous Lineage and Mixed Phenotype Acute Leukaemia
191(8)
Anna Porwit
Marie-Christine Bene
13 Flow Cytometry in Myelodysplastic Syndromes
199(16)
Theresia M. Westers
Arjan A. van de Loosdrecht
14 Future Applications of Flow Cytometry and Related Techniques
215(16)
Marie-Christine Bene
Francis Lacombe
Index 231
Anna Porwit MD, Ph.D. is Professor at the Department of Clinical Sciences, Division Oncology and Pathology, Lunds Universitet, Sweden. She is a co-author of approximately 200 original and review papers, and some chapters in the WHO2008 and 2016 classification of hematopoietic malignancies. Marie Christine Béné, PharmSciD-Ph.D., has been a professor of Immunology at the Faculty of Medicine of Nancy, France, between 1993 and 2012 and is now Professor of Hematology and the head of the Hematology Biology Department in the Université de Nantes, France. She has been co-author with Anna Porwit of several publications as well as chapters of the WHO2008 and 2016 classification of hematopoietic malignancies.