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  • Price: 63,69 €*
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  • Format: 370 pages
  • Pub. Date: 22-Dec-2022
  • Publisher: National Academies Press
  • Language: eng
  • ISBN-13: 9780309274036
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Biological physics, or the physics of living systems, has emerged fully as a field of physics, alongside more traditional fields of astrophysics and cosmology, atomic, molecular and optical physics, condensed matter physics, nuclear physics, particle physics, and plasma physics. This new field brings the physicist's style of inquiry to bear on the beautiful phenomena of life. The enormous range of phenomena encountered in living systems - phenomena that often have no analog or precedent in the inanimate world - means that the intellectual agenda of biological physics is exceptionally broad, even by the ambitious standards of physics.



Physics of Life is the first decadal survey of this field, as part of a broader decadal survey of physics. This report communicates the importance of biological physics research; addresses what must be done to realize the promise of this new field; and provides guidance for informed decisions about funding, workforce, and research directions.

Table of Contents



Front Matter Executive Summary Introduction and Overview PART I: EXPLORING BIG QUESTIONS 1 What Physics Problems Do Organisms Need to Solve? 2 How Do Living Systems Represent and Process Information? 3 How Do Macroscopic Functions of Life Emerge from Interactions Among Many Microscopic Constituents? 4 How Do Living Systems Navigate Parameter Space? PART II: CONNECTIONS 5 Relation to Other Fields of Physics 6 Biology and Chemistry 7 Health, Medicine, and Technology PART III: REALIZING THE PROMISE 8 Education 9 Funding, Collaboration, and Coordination 10 Building an Inclusive Community Appendixes Appendix A: Statement of Task Appendix B: Recommendations Appendix C: Queries to Funding Agencies Appendix D: Agency Missions Appendix E: Details Regarding National Science Foundation and National Institutes of Health Grants Appendix F: Minimal Support Levels Appendix G: Committee Biographies
Executive Summary 1(4)
Introduction And Overview 5(40)
Reader's Guide
6(1)
Defining the Field
7(14)
Connections
21(5)
Challenges
26(3)
A Decadal Survey in Context
29(2)
Findings, Conclusions, and Recommendations
31(14)
PART I EXPLORING BIG QUESTIONS
45(136)
1 What Physics Problems Do Organisms Need To Solve?
47(41)
Energy Conversion
49(12)
Mechanics, Movement, and the Physics of Behavior
61(9)
Sensing the Environment
70(10)
Structures in Space and Time
80(8)
2 How Do Living Systems Represent And Process Information?
88(31)
Information Encoded in DNA Sequence
88(9)
Information in Molecular Concentrations
97(7)
Information in the Brain
104(8)
Communication and Language
112(7)
3 How Do Macroscopic Functions Of Life Emerge From Interactions Among Many Microscopic Constituents?
119(39)
Protein Structure, Folding, and Function
120(9)
Chromosome Architecture and Dynamics
129(5)
Phases and Phase Separation
134(5)
Cellular Mechanics and Active Matter
139(5)
Networks of Neurons
144(8)
Collective Behavior
152(6)
4 How Do Living Systems Navigate Parameter Space?
158(23)
Adaptation
159(7)
Learning
166(4)
Evolution
170(11)
PART II CONNECTIONS
181(62)
5 Relation To Other Fields Of Physics
182(14)
6 Biology And Chemistry
196(23)
Tools for Discovery
196(6)
Molecular and Structural Biology
202(6)
Genes, Genomes, and Evolution
208(2)
Cell and Developmental Biology
210(6)
From Neuroscience to Psychology
216(3)
7 Health, Medicine, And Technology
219(24)
Imaging, Diagnostics, and Treatment
222(5)
Molecular Design
227(4)
Synthetic Biology
231(2)
Predicting and Controlling Evolution
233(3)
Biomechanics and Robotics
236(3)
Neural Networks and Artificial Intelligence
239(4)
PART III REALIZING THE PROMISE
243(74)
8 Education
244(27)
Current State of Education in Biological Physics
246(6)
Strengthening Biological Physics Education
252(15)
Postdoctoral Trajectories
267(2)
Summary
269(2)
9 Funding, Collaboration, And Coordination
271(33)
Current Funding for Research and Education
272(17)
Responding to Challenges and Opportunities
289(9)
User Facilities
298(6)
10 Building An Inclusive Community
304(13)
International Engagement
305(5)
Race and Ethnicity
310(3)
Gender
313(2)
Toward Broader Engagement
315(2)
APPENDIXES
317
A Statement of Task
319(2)
B Recommendations
321(4)
C Queries to Funding Agencies
325(5)
D Agency Missions
330(2)
E Details Regarding National Science Foundation and National Institutes of Health Grants
332(6)
F Minimal Support Levels
338(6)
G Committee Biographies
344