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E-raamat: Advanced Nanomaterials for Point of Care Diagnosis and Therapy

Edited by (Associate Professor, Department of Applied Sciences, JIET, India), Edited by (Director of Research, Valnizen Healthcare Pvt Ltd, India), Edited by (Department of Microbiology, School of Science, RK University, Rajkot, Gujarat, India; Department of Physics)
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  • Ilmumisaeg: 11-Mar-2022
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323900669
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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 11-Mar-2022
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323900669
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Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite.

Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field.

  • Outlines the needs and challenges of point-of-care diagnostics
  • Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing
  • Overviews the different detection methods offered by using nanomaterials
  • Explains the advantages and drawbacks of nanomaterial-based sensing strategies
  • Describes the opportunities offered by technology as a cost-efficient biosensing platform
Contributors xiii
1 Nanomaterials-based biosensors
1(14)
Anirban Das
Varun Rai
Kamalakanta Behera
Ram S. Singh
1.1 Introduction
1(1)
1.2 Classification based on detection techniques
2(9)
1.3 Nanozymes
11(1)
1.4 Conclusion
11(4)
References
12(3)
2 Emerging technology for point-of-care diagnostics: Recent developments
15(28)
Subrata Mondal
Rahul Narasimhan
Ramesh B. Yathirajula
Indrani Medhi
Lidong Li
Shu Wang
Parameswar K. Iyer
2.1 Introduction
15(1)
2.2 Power systems
15(4)
2.3 Technologies involved
19(2)
2.4 Monitoring health parameters
21(6)
2.5 Biomarkers for disease diagnosis
27(10)
2.6 Conclusion and future perspective
37(6)
References
37(6)
3 Quantum dots enabled point-of-care diagnostics: A new dimension to the nanodiagnosis
43(10)
Swayamprabha Sahoo
Ananya Nayak
Ayushman Gadnayak
Maheswata Sahoo
Sushma Dave
Padmaja Mohanty
Jatindra N. Mohanty
Jayashankar Das
3.1 Introduction
43(1)
3.2 Characteristics of quantum dots-based point-of-care testing device
43(2)
3.3 Nanobiosensors for point-of-care diagnostics
45(8)
References
49(4)
4 Nanomaterials-based disposable electrochemical devices for point-of-care diagnosis
53(28)
A.M. Vinu Mohan
4.1 Introduction
53(2)
4.2 Paper-based disposable sensors for point-of-care testing
55(4)
4.3 Screen-printed disposable sensors for point-of-care analysis
59(8)
4.4 Ink-jet printed disposable sensors
67(2)
4.5 Laser-scribed graphene based disposable sensors
69(1)
4.6 Recent advances and future perspectives
70(3)
4.7 Summary
73(8)
Acknowledgment
74(1)
References
74(7)
5 Fabrication of nanomaterials for biomedical imaging
81(20)
Abhishek Sharma
Deepak Panchal
Om Prakash
Purusottam Tripathy
Prakash Bobde
Sukdeb Pal
5.1 Introduction
81(2)
5.2 Bioimaging modalities
83(1)
5.3 Fabrication of nanomaterials for bioimaging
84(8)
5.4 Nanoparticle design considerations: Core and surface fabrication
92(1)
5.5 Fabrication techniques of nanoparticles
93(2)
5.6 Conclusions
95(6)
Acknowledgment
96(1)
References
96(5)
6 Surface modification with nanomaterials for electrochemical biosensing application
101(20)
Sivaprakasam Radhakrishnan
Byoung-Suhk Kim
Sushma Dave
6.1 Introduction
101(1)
6.2 Essential requirement and role of nanomaterials in ideal biosensors development
102(2)
6.3 Fabrication of electrochemical biosensors using nanomaterials
104(10)
6.4 Conclusions, future prospects, and challenges
114(7)
Acknowledgments
115(1)
References
115(6)
7 Nanomaterials for sensors: Synthesis and applications
121(48)
Laxmi R. Adil
Retwik Parui
Mst N. Khatun
Moirangthem A. Chanu
Lidong Li
Shu Wang
Parameswar K. Iyer
7.1 Introduction of nanomaterials
121(1)
7.2 Classification of nanomaterials
121(3)
7.3 Synthesis of nanomaterials
124(10)
7.4 Properties of nanomaterials
134(1)
7.5 Characterization of nanoparticles
134(2)
7.6 Nanomaterials application in sensing
136(23)
7.7 Conclusion and future aspects
159(10)
References
160(9)
8 A comprehensive study toward the treatment of inflammatory diseases through nanoparticles
169(12)
Maheswata Moharana
Satya Narayan Sahu
Subrat Kumar Pattanayak
Fahmida Khan
8.1 Introduction
169(2)
8.2 Computational details
171(1)
8.3 Results and discussion
172(4)
8.4 Conclusions
176(5)
References
177(4)
9 Recent advances of nanomaterial sensor for point-of-care diagnostics applications and research
181(22)
Anshebo G. Alemu
Anshebo T. Alemu
9.1 Introduction
181(1)
9.2 Working principles of nanomaterial sensors
182(1)
9.3 Types of nanosensors
183(1)
9.4 Dimension of nanomaterials sensor
183(5)
9.5 Point-of-care applications
188(8)
9.6 Future perspectives and research
196(1)
9.7 Conclusion
197(6)
Conflicts of interest
197(1)
Acknowledgments
197(1)
References
197(6)
10 Hybrid organic or inorganic nanomaterials for healthcare diagnostics
203(8)
Indu Sharma
Satabdi Bhattacharjee
10.1 Introduction
203(1)
10.2 Classification of organic and inorganic materials
203(1)
10.3 Different types of inorganic and organic nanomaterial in treatment
204(1)
10.4 Applications in healthcare
205(1)
10.5 Prevailing scenario of nanomaterials in diagnostics and therapeutics
206(1)
10.6 Future perspectives and conclusions
207(4)
References
207(4)
11 Carbon nanomaterials: Application as sensors for diagnostics
211(38)
Naveen K. Dandu
Ch. G. Chandaluri
Kola Ramesh
D. Saritha
N. Mahender Reddy
Gubbala V. Ramesh
11.1 Introduction
211(2)
11.2 Carbon-based nanomaterials
213(6)
11.3 Biosensor applications
219(20)
11.4 Conclusion
239(10)
References
239(10)
12 Modification of screen printed biosensors using nanomaterials
249(26)
Silpa P. A.
12.1 Introduction
249(2)
12.2 Classification of nanomaterials for biosensors
251(2)
12.3 Modification of screen printed electrodes using nanomaterials
253(18)
12.4 Advantages of modification
271(1)
12.5 Conclusion
271(4)
References
272(3)
13 Hybrid organic or inorganic nanomaterials for healthcare diagnostics
275(38)
Pallab K. Bairagi
Pravat Rajbanshi
Prateek Khare
13.1 Introduction
275(2)
13.2 Different classes of nanomaterials and their applications
277(5)
13.3 Selection criteria of nanodevices for disease diagnosis
282(4)
13.4 Synthesis of smart nanomaterials
286(5)
13.5 Nanomaterials characterization techniques
291(4)
13.6 Application of hybrid inorganic and organic nanomaterials in healthcare diagnostics
295(5)
13.7 Conclusion
300(13)
References
300(13)
14 Emerging strategies in nanotheranostics: A paradigm shift
313(22)
Jnana R. Sahu
Tejaswini Sahoo
Anulipsa Priyadarshini
Deepak Senapati
Debasis Bisoi
Sabyasachi Parida
Goutam Ghosh
Rojalin Sahu
14.1 Introduction
313(1)
14.2 Nanotheranostics
314(1)
14.3 Metal-based nanomaterials
314(7)
14.4 Polymeric nanomaterials
321(2)
14.5 Silica-based nonmaterial
323(2)
14.6 Carbon nanomaterials
325(1)
14.7 Composite nonmaterial
325(2)
14.8 Other nanomaterials
327(1)
14.9 Conclusion and future scope
328(7)
References
328(7)
15 Nanoparticles in dentistry
335(24)
Debarchita Sarangi
Snigdha Pattanaik
15.1 Introduction
335(4)
15.2 Nanoparticles in dental materials
339(1)
15.3 Nanoparticles in diagnostic dentistry
340(1)
15.4 Nanotechnology in preventive dentistry
341(2)
15.5 Nanoparticles in therapeutic dentistry
343(3)
15.6 Nanoparticles in implant dentistry
346(1)
15.7 Nanoparticles in sterilization and disinfection
347(1)
15.8 Nanotechnology in different branches in dentistry
348(1)
15.9 Conclusion
348(11)
References
349(10)
16 Advanced nanomaterial for point-of-care chemotherapy
359(24)
Soumya S. Panda
Hemlata Das
Saroj Prasad Panda
Spoorthy Kolluri
Sindhu Kilaru
16.1 Introduction
359(1)
16.2 Challenges with conventional chemotherapy agents
359(1)
16.3 Nanotherapeutics to overcome conventional chemotherapy limitations
360(1)
16.4 Nanocarriers in drug delivery systems
361(15)
16.5 Summary
376(7)
References
376(7)
17 Drug loaded nanomaterials for hematological malignancies diagnosis and enhanced targeted therapy
383(16)
Priyanka Samal
Shahani Begum
17.1 Introduction
383(3)
17.2 Different nanomaterials and their fabrication for targeted drug therapy
386(5)
17.3 Cancer diagnosis
391(1)
17.4 Some investigated nanomaterials based imaging techniques
391(1)
17.5 Clearance and toxicological investigation of nanomaterials
392(1)
17.6 Challenges to cancer nanotechnology
393(1)
17.7 Conclusion and future perspective
394(5)
References
395(4)
18 DNA nanotechnology based point-of-care theranostics devices
399(16)
Anjali Rajwar
Vinod Morya
Dhiraj Bhatia
18.1 Introduction
399(2)
18.2 Design and synthesis of DNA-based devices
401(2)
18.3 DNAhydrogels
403(1)
18.4 Characterization of DNA nanodevices
404(1)
18.5 Current applications
405(4)
18.6 Conclusion and future perspectives
409(6)
Acknowledgments
409(1)
Conflict of interest
410(1)
References
410(5)
19 Current trends in theranostic approaches using nanotechnology for oral squamous cell carcinoma
415(8)
Satya Ranjan Misra
Swagatika Panda
Neeta Mohanty
19.1 Introduction
415(1)
19.2 Early diagnosis of oral cancer using nanotechnology
416(2)
19.3 Enhanced treatment of oral cancer using nanotechnology
418(1)
19.4 Conclusion
419(4)
References
419(4)
20 Advanced nanomaterials for point-of-care diagnosis and therapy
423(28)
Sreejita Ghosh
Moupriya Nag
Dibyajit Lahiri
Dipro Mukherjee
Sayantani Garai
Rina Rani Ray
20.1 Introduction
423(1)
20.2 Point-of-care tests and diagnosis
424(1)
20.3 Nanomaterial and its classifications
424(2)
20.4 Applications of nanomaterials in point-of-care diagnosis
426(9)
20.5 Utilization of nanomaterials for point-of-care tests for infectious diseases
435(4)
20.6 Therapeutic applications of nanomaterials
439(6)
20.7 Conclusion
445(6)
References
445(6)
21 Synthesis and applications of carbon nanomaterials-based sensors
451(26)
Ravi Patel
Prakash Bobde
Vishal Singh
Deepak Panchal
Sukdeb Pal
21.1 Introduction
451(1)
21.2 Classification of nanosensors
452(5)
21.3 Study of carbon-based sensor
457(1)
21.4 Synthetic methods of carbon nanomaterials in sensing
458(6)
21.5 Current applications
464(3)
21.6 Conclusions
467(10)
Acknowledgments
467(1)
References
467(10)
22 Nanomaterials for sensors: Synthesis and applications
477(16)
Vinod Nandre
Yogesh Jadhav
Dwiti K. Das
Rashmi Ahire
Sougata Ghosh
Sandesh Jadkar
Kisan Kodam
Suresh Waghmode
22.1 Introduction
477(1)
22.2 Sensors
477(7)
22.3 Nanomaterials
484(2)
22.4 Modification of nanomaterials as a function of size, shape, composition, doping
486(1)
22.5 Applications of nanomaterials in sensor field
486(1)
22.6 Summary and future perspectives
487(6)
Acknowledgment
490(1)
References
490(3)
23 Nanomedicines as an alternative strategy for Fungal disease treatment
493(20)
Swati Goswami
Vijay Kumar
23.1 Introduction
493(1)
23.2 Fungi as human pathogens
493(1)
23.3 Types of fungal infections
494(1)
23.4 Antifungal drugs and their mode of action
495(1)
23.5 Nanomedicine/nanotherapy: An answer to antifungal resistance
496(7)
23.6 Antifungal peptides as antifungal drugs/delivery system
503(2)
23.7 Conclusion
505(8)
References
505(8)
24 Technological advancement in nano diagnostics point of care test development for biomedical application
513(28)
Anulipsa Priyadarshini
Tejaswini Sahoo
Deepak Senapati
Sabyasachi Parida
Rojalin Sahu
24.1 Introduction
513(1)
24.2 Classification of nanosensors
514(3)
24.3 Synthesis
517(2)
24.4 Metal and noble metal nanomaterials as nanosensors
519(3)
24.5 Metal oxide nanomaterials as nanosensors
522(3)
24.6 Carbon-based nanomaterials as nanosensors
525(3)
24.7 Polymer nanomaterials as nanosensors
528(3)
24.8 Bionanomaterials as nanosensors
531(2)
24.9 Electrochemical sensors for biomedical application
533(2)
24.10 Conclusion
535(6)
References
535(6)
25 Smart and intelligent vehicles for drug delivery: Theranostic nanorobots
541(24)
Vishakha Dave
Medha Pandya
Rakesh Rawal
S.P. Bhatnagar
Rasbindu Mehta
25.1 Introduction
541(1)
25.2 Magnetic fluid as a smart material
542(1)
25.3 Physical properties of magnetic fluids
543(2)
25.4 Engineering of magnetic fluid for biomedicine applications
545(2)
25.5 Nanorobots in diagnostics
547(3)
25.6 A drug delivery vehicle
550(7)
25.7 Safety measurements and risks
557(1)
25.8 Conclusion and prospects
557(8)
References
558(7)
Index 565
Dr. Sushma Dave received a master of science and PhD in analytical, electrochemistry, and environmental chemistry from the Biosensor Lab in the Chemistry Department of Jai Narayan Vyas University, Jodhpur. She is involved continuously in the field of higher education teaching pure, applied chemistry, cheminformatics, nanotechnology, electrochemistry, biology, solid waste management, wastewater treatment, and environmental chemistry to students of engineering and basic sciences. She also served as a Research Associate in the Soil Biochemistry and Microbiology Division, CAZRI, Jodhpur. She has published and presented over 50 papers in international and national journals, conferences and participated in various workshops and training programs. Her areas of interest are electrochemistry, biosensors environmental science, nanotechnology, biochemistry, cheminformatics, immunoinformatics, and drug repurposing.

Dr. Das received his PhD in biotechnology and served as a Scientist at the IBSD, DBT, Government of India. He is the Founder and CEO of Valnizen which deals with regulatory documents and healthcare compliances and support services to African and southeast Asian countries. He has served as a Joint Director of the Gujarat State Biotechnology Mission, DST, and Joint Director to Gujarat Biotechnology Research Centre, DST, both from the Government of Gujarat. He has served as a Director of the Savli Technology and Business Incubator, DST, Government of Gujarat, India. He was actively involved in the development and implementation of various policies and action plans like biotechnology policy, innovation policy, interpole disaster management policy, start-up policy for many universities and governments. His research team is involved in addressing societal challenges via cutting-edge research, namely, the development of molecular diagnostics for infectious diseases, the development of universal vaccine candidate for emerging diseases, the development of miRNA-based targeted therapeutics, and artificial intelligence in healthcare applications.

Dr. Sougata Ghosh is an Associate Professor in the Department of Microbiology at RK University, India, with a B.Sc., M.Sc., and Ph.D. in Microbiology from Savitribai Phule Pune University. He also serves as a Visiting Professor at Kasetsart University in Thailand and Northeastern University in the USA. Ghosh has led a DBT-funded Foldscope Research Project, filed seven patents, edited ten books, and authored 256 publications with 5,258 citations. He has spoken at numerous international conferences and reviews for 79 journals. A life member of the Association of Microbiologists of India, he has been recognized in Stanford's World Top 2% Scientists Ranking. His research focuses on nanobiotechnology, applied microbiology, and bioremediation.