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E-raamat: Advances in Ophthalmology and Optometry 2016: Advances in Ophthalmology and Optometry 2016

, , , (Hawthorn Medical Associa), , (Associate Professor), , , (Professor and Chair, Department of Ophthalmology, Drexel University College of Medicine; Adjunct Professor of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, USA),
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  • Ilmumisaeg: 15-Oct-2016
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323509206
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  • Formaat: EPUB+DRM
  • Sari: Advances
  • Ilmumisaeg: 15-Oct-2016
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323509206
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Advances in Ophthalmology and Optometry reviews the most current practices in both ophthalmomlogy and optometry. A distinguished editorial board, headed by Dr. Myron Yanoff, identifies key areas of major progress and controversy and invites expert ophthalmologists and Optometrists to contribute original articles devoted to these topics. These insightful overviews bring concepts to a clinical level and explore their everyday impact on patient care. Topics will cover all specialty areas, highlighting the most current and relevant information in the field.

Arvustused

"a comprehensive volume ... We would recommend the book to ophthalmology"

residents-in-training, general ophthalmologists and optometrists.

Associate Editors iii
Contributors v
Preface: Sorting Through the Confusion xxiii
Myron Yanoff
Section I Cornea and External Diseases
Novel Diagnostics and Therapeutics in Dry Eye Disease
Daniel Sarezky
Mina Massaro-Giordano
Vatinee Y. Bunya
Introduction
2(1)
Diagnostics
2(8)
Tear Osmolarity
2(1)
Oculus Keratograph
3(2)
Interferometry
5(1)
Matrix Metalloproteinase-9 Detection
6(1)
Confocal Microscopy
7(2)
Fluorophotometry
9(1)
Therapeutics
10(5)
Intense Pulsed Light
10(1)
LipiFlow
11(1)
Meibomian Gland Probing
12(1)
MiBoFlo Thermoflo
12(1)
BlephEx
12(1)
Scleral Lens
13(2)
Amniotic Membrane
15(1)
Summary
15(6)
Review of Descemet Stripping Automated Endothelial Keratoplasty Versus Descemet Membrane Endothelial Keratoplasty
Purak C. Parikh
Introduction
21(1)
Significance
22(5)
Visual outcomes
22(1)
Complications
23(2)
Endothelial cell density
25(1)
Patient satisfaction
26(1)
Graft preparation
26(1)
Transitioning from Descemet stripping automated endothelial keratoplasty to Descemet membrane endothelial keratoplasty
26(1)
Patient selection and counseling
27(1)
Future directions
27(1)
Summary
28(3)
Section II Cataract and Refractive Surgery
Pseudoexfoliation Syndrome and Cataract Surgery
Alan S. Crandall
Video content accompanies this article at: www.advancesinophthalmology.com.
Introduction
31(1)
Cataract surgery
32(10)
Divide and conquer
33(8)
The IOL selection in pseudoexfoliation syndrome
41(1)
Summary
42(3)
The Use of Temporary and Permanent Capsular Devices in Eyes with Compromised Zonules
Alan S. Crandall
Video content accompanies this article at: www.advancesinophthalmology.com.
Introduction
45(1)
Capsule support devices
46(2)
Capsular tension segments
48(2)
Capsular tension rings
50(1)
Modified capsular tension rings
50(1)
Summary
51(2)
Section III Uveitis
Therapeutic Options and Strategies for the Uveitis Patient
Jessica Ackert
Introduction
53(1)
Significance
54(2)
Present relevance and future avenues to consider or to investigate; how this article may change the approach to the subject
56(1)
Summary/discussion
57(2)
Follow-up on the Longitudinal Study of the Ocular Complications of Human Immunodeficiency Virus/AIDS
Meghan Berkenstock
Jessica Ackert
Background
59(1)
Epidemiology
60(1)
Diagnosis and management
60(2)
Non-cytomegalovirus retinitis infections
62(1)
Noninfectious ocular complications
63(1)
Cataract risk
63(1)
Epidemiology and discussion
63(1)
Age-related macular degeneration
64(1)
Epidemiology
64(1)
Human immunodeficiency virus neuroretinal disorder
64(1)
Summary
65(4)
Retinal Vasculitis
Brian K. Do
Jerome Giovinazzo
Introduction
69(1)
Epidemiology
70(1)
Associated systemic and local diseases
71(1)
Pathophysiology
71(2)
Diagnosis
73(6)
History
73(1)
Laboratory testing
73(1)
Signs/associated clinical findings
74(2)
Symptoms
76(1)
Ancillary testing
77(2)
Management
79(2)
Immunosuppressive agents
80(1)
Biologics
80(1)
Laser photocoagulation and anti-vascular endothelial growth factor
81(1)
Future avenues
81(1)
Summary
82(3)
Section IV Vitreoretinal Disease
Recent Innovations in Stem Cell Therapy for Retinal Disease
Adnan Mallick
Ronni M. Lieberman
Introduction
85(1)
Types of stem cells
86(3)
Embryonic stem cells
87(1)
Mesenchymal stem cells
88(1)
Induced pluripotent stem cells
89(1)
Retina progenitor cells
89(1)
Neural stem cells or human central nervous system stem cells
89(1)
Animal models
89(1)
Very small embryonic-like stem cells
89(1)
Rodents
90(1)
Larger animals
90(1)
Mechanisms of stem cell transplantation
90(2)
Diseases treated with stem cell therapy
92(8)
Age-related macular degeneration
92(8)
Retinitis pigmentosa
100(2)
Current therapy
100(1)
Ongoing research and clinical trials
100(2)
Stargardt
102(3)
Current therapy
102(1)
Ongoing research and clinical trials
102(3)
Other retinal disease
105(2)
Summary
107(4)
Updates on the Management of Diabetic Macular Edema with New-Generation Intravitreal Injectable Drugs
Jennifer C. Larson
Mihai Mititelu
Introduction
111(3)
Epidemiology
111(1)
Pathophysiology
112(1)
Diagnosis
112(2)
Diabetic macular edema management
114(9)
Systemic risk factor control
114(1)
Photocoagulation
114(1)
Vitrectomy surgery
115(1)
Intravitreal injection of vitreolysis agents
115(1)
Intravitreal injection of corticosteroids
115(1)
Nonsteroidal anti-inflammatory drugs
116(1)
Intravitreal injection of anti-vascular endothelial growth factor agents
117(3)
New-generation intravitreal injectable drugs in development
120(3)
Summary
123(6)
Acknowledgments
126(3)
27-Gauge Vitrectomy: The Future of Posterior Segment Surgery?
Alan Sheyman
Albert Lin
Ronni M. Lieberman
Introduction
129(2)
The road to minimally invasive vitreous surgery
129(1)
Twenty-seven gauge vitrectomy
130(1)
Advantages
131(1)
Surgical indications
131(1)
Improved vitrector speed and precision
131(1)
Intraoperative optical coherence tomography
132(1)
Challenges
132(1)
Summary
133(2)
Section V Oculoplastics
The Ultrasonic Bone Aspirator in Endoscopic Dacryocystorhinostomy
Lama Khatib
William R. Katowitz
Introduction
135(1)
External dacryocystorhinostomy and endoscopic dacryocystorhinostomy: a brief history
136(1)
The ultrasonic bone aspirator: an overview
136(5)
Endoscopic dacryocystorhinostomy: a brief description of the procedure
139(2)
Surgical success
141(3)
Success rates of endoscopic dacryocystorhinostomy and its counterparts in the literature
142(1)
Surgical success of the ultrasonic bone aspirator in endoscopic dacryocystorhinostomy
142(1)
Factors affecting success rates
143(1)
Time taken to perform the osteotomy
143(1)
Complications
143(1)
Advantages of the ultrasonic bone aspirator
144(1)
Summary
144(4)
Orbital Manifestations of Immunoglobulin G4-Related Disease: Current State of Knowledge
Sunny Shen
Dion Paridaens
Anita Chan
Geoffrey E. Rose
Introduction
148(2)
Systemic immunoglobulin G4-related disease
150(12)
Definition and diagnosis of immunoglobulin G4-related disease
150(1)
Histologic diagnosis of immunoglobulin G4-related disease
150(2)
Epidemiology, etiology, and clinical relevance of immunoglobulin G4-related disease
152(1)
Orbital immunoglobulin G4-related disease
153(1)
Presentation and differential diagnosis of immunoglobulin G4-related orbital disease
153(1)
Imaging of immunoglobulin G4-related orbital disease
154(2)
Histology of immunoglobulin G4-related orbital disease
156(5)
Treatment of immunoglobulin G4-related orbital disease
161(1)
Summary
162(3)
Acknowledgments
162(3)
Scar Modulation
Kian Eftekhari
Raymond S. Douglas
Guy G. Massry
Introduction
165(1)
Stages of wound healing
166(1)
Fetal wound healing
166(1)
Hypertrophic scars and keloids
167(1)
Patient considerations before scar modulation
167(1)
Timing of scar modulation
168(1)
Approaches to scar modulation
169(1)
Surgical scar revision
169(1)
Scar resurfacing
169(1)
Nonsurgical approaches to scar modulation
169(7)
Triamcinolone
169(3)
Antimetabolites
172(1)
Neurotoxins
173(1)
Hyaluronic acid gel
174(2)
Other agents and future therapies
176(1)
Summary
176(5)
Section VI Pediatric Opthalmology
Amblyopia in the Twenty-First Century
Julia Byrd
Aparna Ramasubramanian
Introduction
181(1)
Significance/in-depth analysis
182(5)
Prevalence
182(1)
Mechanism of amblyopia
182(1)
Treatment
183(4)
Current relevance and future avenues to investigate
187(3)
Levodopa
187(1)
Acupuncture
188(1)
Binocular treatment
189(1)
Burden of amblyopia treatment
190(1)
Summary/discussion
190(3)
Telemedicine in Retinopathy of Prematurity
Anand Vinekar
Chaitra Jayadev
Bhujang Shetty
Introduction
193(1)
Significance
194(12)
The camera
195(1)
Telemedicine software
195(1)
Data and image management
196(1)
The retinopathy of prematurity specialist
196(1)
The imaging team
197(3)
Training of the imagers
200(1)
The project manager
200(1)
Other associations
201(5)
Future research and trends
206(1)
New wide-field imaging cameras
206(1)
Online training
206(1)
Software and autoanalysis
206(1)
Crowdsourcing in retinopathy of prematurity
206(1)
Government and financial support
206(1)
Changing paradigm in retinopathy of prematurity screening
207(1)
Summary
207(4)
Congenital Cataract: Lessons Learned from Infant Aphakia Treatment Study
Bharti R. Nihalani
Introduction
211(1)
Infant Aphakia Treatment Study: study design and clinical measures at enrollment
212(1)
Lessons learned from Infant Aphakia Treatment Study
213(1)
Morphology of cataract
214(1)
Intraocular lens power calculation and early refractive outcomes
215(1)
Contact lenses power
216(2)
Visual acuity outcomes
218(1)
Complications
218(3)
Glaucoma
221(2)
Strabismus
223(1)
Stereopsis
223(1)
Nystagmus and fixation instabilities
224(1)
Occlusion therapy
224(1)
Parenting stress
225(1)
Total costs incurred by each treatment group
225(1)
Summary
226(5)
Section VII Neuro-opthalmology
Objective Measures of Visual Function in Papilledema
Heather E. Moss
Introduction
231(1)
Significance
232(12)
Basis of objective visual function measurements
232(1)
Visual evoked potential
233(6)
Full-field electroretinography and the photopic negative response
239(4)
Pattern electroretinography
243(1)
Pupillary light response
244(1)
Current clinical relevance
244(1)
Future avenues for investigation
244(1)
Summary/discussion
245(4)
New Advancements in Migraine Assessment and Treatment
Shannon J. Beres
Grant T. Liu
Introduction
249(1)
Classification of headache
250(1)
Classification of migraine
250(4)
Migraine without aura
251(1)
Migraine with aura
252(1)
Complications of migraine visual aura
252(1)
Migraine with aura: red flags
253(1)
Other migraine-related visual conditions
253(1)
Etiology of migraine
254(1)
Management of migraine
255(2)
Acute therapies
255(1)
Preventive therapies
256(1)
Bio-behavioral strategies
256(1)
Novel product strategies
256(1)
Future avenues
257(1)
Summary
258(3)
Section VIII Opthalmic Pathology and Ocular Oncology
Update on Tumor-Node-Metastasis Staging for Uveal Melanoma
Alice Yang Zhang
Sherveen Salek
Mary Aronow
Introduction
261(1)
Prognostic indicators in uveal melanoma
262(1)
Classification of uveal melanoma
263(1)
Tumor-node-metastasis staging for uveal melanoma
264(2)
Updates to the 7th edition of tumor-node-metastasis staging for uveal melanoma
266(1)
Size category
266(1)
Ciliary body involvement
267(1)
Extraocular extension
267(1)
Validation of tumor-node-metastasis staging for uveal melanoma
267(2)
Survival based on size
268(1)
Survival based on ciliary body involvement and extraocular extension
268(1)
Survival based on overall stage
268(1)
Iris melanoma
269(1)
Future directions
269(1)
Summary
270(3)
Intravitreal Chemotherapy for Retinoblastoma
Roomasa Channa
Jithin Yohannan
Mary Aronow
Introduction
273(1)
Indications and historical aspects
274(1)
Therapeutic agents
275(1)
Melphalan
275(1)
Topotecan
276(1)
Combination therapy
276(1)
Technique and safety considerations
276(1)
Efficacy of intravitreal chemotherapy
277(3)
Side effects of intravitreal chemotherapy
280(1)
Safety considerations
280(1)
Relevance to current treatment of retinoblastoma
281(1)
Limitations
282(1)
Contraindications
282(1)
Future directions
282(1)
Adenoviral vectors
283(1)
Summary
283(4)
Section IX Optometry
The Amblyopia Treatment Studies: Implications for Clinical Practice
Angela M. Chen
Susan A. Cotter
Introduction
287(2)
Signs, symptoms, and quality-of-life concerns
288(1)
Historical perspective on amblyopia treatment
288(1)
Amblyopia Treatment Studies
288(1)
Results and clinical implications
289(13)
Prescribing guidelines for refractive error correction
289(1)
Optical treatment studies
290(2)
Forms of occlusion
292(4)
Treatment of older children with amblyopia
296(2)
Residual amblyopia
298(2)
Recurrence of amblyopia
300(1)
Long-term follow-up
300(1)
Role of near activities
301(1)
Summary
302(5)
Acknowledgments
303(4)
Traumatic Brain Injury: Visual Consequences, Diagnosis, and Treatment
Kenneth J. Ciuffreda
Diana P. Ludlam
Naveen K. Yadav
Preethi Thiagarajan
Introduction
307(6)
Traumatic brain injury: the visual consequences, diagnosis, and treatment
313(11)
Tier 1
313(4)
Tier 2
317(3)
Tier 3
320(3)
Tier 4
323(1)
Current relevance
324(3)
Military encounters
324(1)
Sports
325(1)
Aging
326(1)
Air pollution
327(1)
Future avenues to investigate
327(1)
Natural history of traumatic brain injury
327(1)
Quality-of-fife assessment questionnaire
328(1)
Clinical trials
328(1)
Other populations
329(1)
Further development of objective tests for detection of concussion/mild traumatic brain injury
330(1)
Objective visual biomarker(s) for concussion/mild traumatic brain injury
330(1)
Automation
330(1)
Summary
330(6)
Age-related Macular Degeneration Beyond the Age-related Eye Disease Study II
Stuart Richer
Natalia A. Popenko
Dorothy Hitclunoth
Bill Sardi
Steven G. Pratt
Paul Chous
Lawrence Ulanski II
Shana Patel
Shivani Sockanathan
Introduction
336(1)
Supportive nutrients beyond Age-related Eye Disease Study I and II
337(5)
Glutathione master antioxidant and selenium status
337(2)
Vitamin D status
339(1)
Tocotrienols and tocopherols
340(1)
Bioflavonoids
340(1)
Magnesium shortage with suboptimal magnesium2+/calcium2+ ratio affecting 50% of the United States population
340(1)
Maintenance of an antiinflammatory omega-6/omega-3 ratio and a high Holman Index with adequate docohexanoic acid intake
341(1)
Embracing high-dose zeaxanthin
341(1)
Embracing nitric oxide-promoting activities/nutrients for sustained choroidal vasodilation
342(1)
Summary
342(1)
Minimizing environmental stress
343(11)
Chronic ascorbate depletion/dosing considerations
343(1)
Excess simple sugars against concurrent cellular ascorbate depletion (vitamin C deficiency)
344(3)
Folypharmacy and drug-induced nutrient and energy depletion
347(1)
Ubiquitous modern copper plumbing (United States)
347(2)
Labile iron toxicity
349(3)
Iatrogenic calcification via overzealous calcium++ supplementation
352(1)
Maintaining a healthy gastrointestinal microbiome
353(1)
Genetics, zinc epigenetics, and hormetic adaptive response
354(9)
Nutrigenomics
354(1)
Epigenetics, the epigenome, and hormesis in postdarwinian biology
355(2)
General principles: actions of sirtuin 3
357(1)
General principles: hormesis
357(6)
Therapeutic intervention
363(2)
Summary
365(6)
Section X Glaucoma
Recent Advances in the Pharmacotherapy for Glaucoma
Joseph M. Ortiz
Introduction
371(3)
Discussion
374(10)
New drugs in development
382(2)
Summary
384(5)
New Glaucoma Surgical Procedures
Victoria Addis
Monica Zhang
Eydie Miller-Ellis
Introduction
389(1)
Significance
390(16)
Ab interno procedures
390(11)
Ab externo procedures
401(1)
Future directions
402(4)
Summary
406