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E-raamat: Advances in Ophthalmology and Optometry, E-Book 2022: Advances in Ophthalmology and Optometry, E-Book 2022

Edited by (Professor and Chair, Department of Ophthalmology, Drexel University College of Medicine; Adjunct Professor of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, USA)
  • Formaat: PDF+DRM
  • Sari: Advances
  • Ilmumisaeg: 27-Aug-2022
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323961882
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  • Formaat: PDF+DRM
  • Sari: Advances
  • Ilmumisaeg: 27-Aug-2022
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323961882
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Advances in Ophthalmology and Optometry reviews the year’s most important findings and updates within the field in order to provide clinicians with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Myron Yanoff, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in ophthalmology and optometry inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care.
  • Provides in-depth, clinical reviews in ophthalmology and optometry, providing actionable insights for clinical practice.

  • Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Associate Editors vii
Contributors ix
Preface: Looking Backward and Forward xxxv
Myron Yanoff
Optometry: Bioptic Driving in the United States
Laura Windsor
Richard Windsor
Introduction
1(1)
History of bioptics and driving in the United States
2(2)
A legal pathway for bioptic driving
3(1)
Controversies and research in bioptic driving
4(2)
Wearing the bioptic only to obtain licensure
4(1)
Ring scotoma of the telescope
5(1)
Bioptic driving safety
5(1)
Bioptics in the United States
6(2)
Visual acuities
7(1)
Visual fields
8(1)
Bioptic training
8(1)
Nighttime driving
8(1)
Bioptic telescope requirements
8(1)
Ocular conditions and ability to drive
8(6)
Other factors in patient selection for bioptic driving
14(2)
Visual processing skills and cognitive abilities
14(1)
Motor skills and functioning
15(1)
Age and maturity
15(1)
Medical and medication history
15(1)
Emotional/mental status
15(1)
Family support
15(1)
Designing the bioptic system
16(2)
Power and position of the telescope
16(1)
Field of view through the telescope
17(1)
Adaptability of the bioptic for light and glare issues
17(1)
Training the bioptic driver
18(3)
Training to use the bioptic
19(1)
Training with the certified driver rehabilitation specialist
19(1)
After bioptic licensure
20(1)
Vehicle modifications for bioptic drivers
21(1)
Vehicle selection
21(1)
Global positioning systems
21(1)
Speedometer
21(1)
Windshield and dash glare
21(1)
The Indiana program for visually impaired drivers
22(1)
Part 1 Waivered Drivers
22(1)
Part 2 Bioptic Drivers
22(1)
The Faces of Bioptic Driving
23(3)
Dr. Dennis Kelleher: First Legally Licensed Bioptic Driver in the United States
26(1)
Future research in bioptic driving
26(1)
Summary
27(1)
Clinics care points
27(4)
Disclosure
27(4)
The Use of B-Scan Ultrasound in Primary Eye Care
Elena Z. Biffi
Benjarnin Young
Joseph Edward Kane Jr.
Mehdi Najafi
Introduction
31(1)
Indications and contraindications
32(1)
Principles of B-scan ultrasound examination
33(3)
B-scan description
33(1)
Probe positions and image interpretation
34(2)
Clinical examination principles
36(1)
B-scan applications in clinical care
36(10)
Vitreous diseases
36(3)
Retinal diseases
39(3)
Choroidal diseases
42(2)
Optic nerve diseases
44(2)
Advances in ultrasonography
46(1)
Summary
47(1)
Clinics care points
47(1)
Disclosure
47(4)
Nonsurgical Treatment of Strabismus
Marie L. Bodack
Introduction
51(1)
Significance/present relevance
52(12)
Esotropia
52(1)
Observation
52(1)
Lens correction
53(2)
Occlusion
55(1)
Prism correction
56(1)
Vision therapy/orthoptics
57(2)
Exotropia
59(1)
Observation
59(1)
Lenses
60(1)
Overminus lenses
60(1)
Occlusion
61(2)
Prism
63(1)
Summary
64(1)
Clinics care points
65(1)
Disclosure
66(5)
Pediatric
Update on Pediatric Optic Neuritis
Sravanthi Vegunta
Introduction
71(1)
Significance
72(11)
Overview of pediatric optic neuritis
72(4)
Multiple sclerosis-associated optic neuritis
76(1)
Myelin oligodendrocyte giycoprotein-associated disease optic neuritis
76(4)
Neuromyelitis optica spectrum disorder optic neuritis
80(3)
Other causes of optic neuritis
83(1)
Relevance and future avenues to consider
84(1)
Summary
84(5)
Acknowledgments
85(4)
Genetics of Congenital Cataract
Reddin Ahmad
Suzannah Bell
Mariya Moosajee
Introduction
89(1)
Cause and classification
90(1)
Significance
91(1)
Nonsyndromic congenital cataract
91(19)
Crystallins
91(4)
Cytoskeletal structural proteins
95(1)
Membrane proteins
95(3)
Transcription factors
98(12)
Syndromic congenital cataract
110(2)
Down syndrome (Trisomy 21)
110(1)
Patau syndrome (Trisomy 13)
110(1)
Lowe syndrome
110(1)
Norrie disease
110(1)
Nance-Horan syndrome
111(1)
Myotonic dystrophy 1
111(1)
Neurofibromatosis type 2
111(1)
Zellweger spectrum disorder
111(1)
Rothmund-Thompson syndrome
112(1)
Cockayne syndrome
112(1)
Cerebrotendinous xanthomatosis
112(1)
Galactosemia
112(1)
Acquired causes
112(1)
Congenital infections
112(1)
Trauma
113(1)
Other common causes of cataract in children
113(1)
Uveitic cataract and steroid-related cataract
113(1)
Radiation cataract
113(1)
Relevance
113(1)
Management of childhood cataract
113(1)
Genetic testing
114(1)
Multidisciplinary care
114(1)
Summary
114(1)
Clinics care points
115(4)
Disclosure
115(4)
Pediatric Graft-Versus-Host Disease
Kerri Mclnnis-Smith
Holly K. Miller
Aparna Ramasubramanian
Background
119(16)
Hematopoietic stem cell transplant
120(1)
Pathophysiology of systemic GVHD
121(1)
Incidence of Chronic GVHD
121(1)
Diagnosis and Classification of Systemic GVHD
122(2)
Grading of Systemic Disease Severity
124(1)
Risk Factors for Systemic GVHD
125(1)
Prognosis
125(1)
Ocular GVHD
125(5)
Mainstays and recent developments in therapy
130(5)
Summary
135(1)
Clinics care points
135(1)
Disclosure
135(4)
Ophthalmic Pathology & Ocular Oncology
Fluorescence In Situ Hybridization in Ocular Oncology
Seema Sen
Shahzan Anjum
Mehar Chand Sharma
Introduction
139(1)
Significance of fluorescence in situ hybridization
140(5)
General Principle of Fluorescence In Situ Hybridization
141(1)
Detailed Fluorescence In Situ Hybridization Protocol for Tissue Sections
141(1)
Ocular Lymphomas
142(1)
Uveal Melanomas
143(1)
Adenoid Cystic Carcinoma
144(1)
Present relevance and future of fluorescence in situ hybridization
145(1)
Clinics care points
146(5)
Disclosure
148(3)
Intra-arterial Chemotherapy for Retinoblastoma: An Update
Bhavna Chawla
Navneet Sidhu
Shailesh Gaikwad
Introduction
151(1)
History
152(1)
Intra-arterial chemotherapy terminology
153(1)
Procedure
153(1)
Intra-arterial chemotherapy drugs
154(1)
Significance of intra-arterial chemotherapy
155(1)
Complications of intra-arterial chemotherapy
156(1)
Local
156(1)
Systemic
156(1)
What's new in intra-arterial chemotherapy?
157(1)
Treatment Approaches
157(1)
Drugs
157(1)
Patient profile
157(1)
Summary
157(1)
Clinics care points
158(3)
Disclosure
159(2)
Advances in Pediatric Periocular Vascular Neoplasms
Kasturi Bhattacharjee
Aditi Mehta
Vatsalya Venkatraman
Introduction
161(1)
Significance
162(8)
Vascular tumors
162(3)
Vascular malformations
165(4)
Secondary orbital involvement
169(1)
Present relevance and future avenues to consider
170(3)
Summary
173(1)
Clinics care points
174(3)
Disclosure
174(3)
Cataract & Refractive Surgery
Femtosecond Laser-Assisted Cataract Surgery
Emily Chang
Amy Zhang
Introduction
177(1)
Femtosecond laser technology
178(1)
Clear corneal incision
178(1)
Anterior capsulectomy
179(2)
Nuclear fragmentation
181(2)
Astigmatism management
183(1)
Summary
183(1)
Clinics care points
184(1)
Disclosure
184(3)
Advanced Technology Intraocular Lenses
Mariam S. Hamid
Man Li Jin
Kevin J. Everett
Introduction
187(1)
Significance
188(6)
Accommodative Lenses
188(1)
Multifocal Lenses
189(2)
Optical Side Effects in Multifocal Intraocular Lenses
191(1)
Extended-Vision Intraocular Lens
192(1)
Monofocal Intraocular Lenses with Increased Depth of Focus
193(1)
Light Adjustable Intraocular Lenses
193(1)
Phakic Intraocular Lenses
194(1)
Discussion, future considerations, and summary
194(3)
Clinics care points
197(4)
Vitreoretinal Disease
Diagnostic and Treatment Considerations for Macular Holes
Rupak Bhuyan
Jeffrey Brown
Robin Ginsburg
Introduction
201(2)
Significance
203(8)
Nonsurgical treatment
203(1)
Surgery
204(7)
Present relevance and future avenues
211(3)
Topical agents
211(1)
Ocriplasmin
212(1)
Pneumatic vitreolysis
212(1)
Internal limiting membrane staining
213(1)
Glial plug after internal limiting membrane manipulation
213(1)
Intraoperative optical coherence tomography
213(1)
Autologous mesenchymal stem cell transplantation
213(1)
Autologous retinal transplantation
214(1)
Summary
214(2)
Clinical care points
216(1)
Disclosure
216(1)
Supplementary data
216(4)
Peripheral Retinal Degenerations and Treatment Options
George Jiao
Marib Akanda
Ronni M. Lieberman
Benign lesions
220(3)
Peripheral retinal drusen
220(1)
Paving-stone (cobblestone) degeneration
220(1)
Retinal pigment epithelium hyperplasia
220(1)
Retinal pigment epithelium hypertrophy
221(1)
Peripheral cystoid degeneration
222(1)
Snowflake degeneration
222(1)
Pars plana cysts
222(1)
Pearl degeneration
222(1)
White-with-pressure and white-without-pressure
222(1)
Lesions predisposing to retinal detachment
223(5)
Lattice degeneration
223(1)
Senile retinoschisis
224(2)
Vitreoretinal tufts
226(1)
Meridional folds
226(1)
Enclosed ora bays
226(1)
Peripheral retinal excavations
226(1)
Chorioretinal atrophy
227(1)
Dark-without-pressure
227(1)
Snail track degeneration
227(1)
Retinal Tears and Holes
228(3)
Dialysis
228(1)
Horseshoe tear
228(1)
Operculated round tear
229(1)
Atrophic round hole
230(1)
Treatment options for lattice peripheral degeneration
231(1)
Summary
232(1)
Clinics care points
232(5)
Disclosure
233(4)
Update on Retinal and Ocular Imaging
Samuel Gelnick
Minh Trinh
Ronni M. Lieberman
Background and introduction
237(1)
Optical coherence tomography
238(4)
Fundus photography
242(4)
Artificial intelligence-deep learning
246(1)
Adaptive optics
247(1)
Teleophthalmology
248(1)
Types of teleophthalmology
249(1)
Diabetic screening
249(1)
Retinopathy of prematurity
249(1)
Future directions
249(1)
Clinics care points
250(3)
Disclosure
250(3)
Glaucoma 30-Gauge Needle in Glaucoma/Anterior Segment Management
Ramesh Ayyala
Alireza Baradaran-Rafii
Jacob Liechty
Introduction
253(1)
Preparation of the patient
254(1)
Follow-up after slit lamp procedures
254(1)
Indications and procedure description
254(5)
Bleb needling revision for scarred, fibrosed blebs
254(2)
Bleb needling revision for encapsulating/encapsulated blebs following Ahmed glaucoma valve implantation
256(1)
Paracentesis to decrease intraocular pressure
257(1)
Anterior chamber reformation
257(1)
Suturing at the slit lamp
258(1)
Suture removal
258(1)
Injections
258(1)
Ahmed glaucoma valve removal
259(1)
Unplugging sclerotomy
259(1)
Corneal procedures
259(2)
DSEAK-related issues and 30G needle
259(1)
Vitreous strand release
260(1)
Astigmatic keratotomy
260(1)
Summary
261(1)
Disclosure
261(1)
Supplementary data
261(2)
Neuro-ophthalmology Screening for Plaquenil
Pushpinder Kanda
Stuart Coupland
Chloe Gottlieb
Lynca Kantungane
Rustum Karanjia
Introduction
263(3)
Plaquenil screening modalities
266(1)
Automated visual fields
267(3)
Spectral-domain optical coherence tomography
270(1)
Fundus autofluorescence
270(1)
Multifocal electroretinogram
271(2)
Current trends and future research
273(2)
Summary
275(1)
Clinics care points
276(4)
Disclosure
276(4)
Update on Optic Neuritis in Adults: Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease
Serena Li
Rahul A. Sharma
Benson S. Chen
Introduction
280(1)
Diagnosis
280(4)
Demographics
280(2)
Clinical features
282(1)
Radiologic features
283(1)
Acute management
284(2)
Long-term management
286(3)
Clinically isolated syndrome and multiple sclerosis
287(1)
Neuromyelitis optica spectrum disorder
288(1)
Myelin oligodendrocyte glycoprotein antibody associated diseases
289(1)
Prognosis
289(1)
Future avenues
290(1)
Summary
291(1)
Clinics care points
291(4)
Disclosure
292(3)
Efficacy and Safety of Tocilizumab in the Treatment of Ocular Manifestations in Giant Cell Arteritis
Nooran Badeeb
Rustum Karanjia
Introduction
295(1)
Methodology
296(1)
Selection criteria
297(1)
Results
297(1)
Significance
297(10)
Visual outcomes reported with Tocilizumab
299(6)
Duration of treatment with Tocilizumab
305(1)
Administration of Tocilizumab
306(1)
Safety and side effects of Tocilizumab
306(1)
Summary
307(1)
Clinics care points
307(5)
Acknowledgments
308(1)
Disclosure
308(4)
Corona virus Disease 2019-Related Health Disparities in Ophthalmology with a Retrospective Analysis at a Large Academic Public Hospital
Y. Grace Chung
Christie M. Person
Jacquelyn O'Banion
Susan A. Primo
Introduction
312(1)
Significance
313(5)
COVLD-19 disproportionate impact
313(1)
COVLD-19 related health care disparities in ophthalmology
313(1)
COVLD-19 related ophthalmic manifestations
314(4)
Relevance and future avenues
318(1)
Conclusion
319(1)
Summary
320(5)
Disclosure
320(5)
Cornea and External Diseases
Stepwise Approach to the Diagnosis and Management of Dry Eye and Ocular Surface Disease
Jennifer B. Nadelmann
Angela Gupta
Caroline W. Chung
Stephen E. Orlin
Introduction 325(58)
Significance
326(10)
Approach to diagnosis
326(4)
Clinical examination
330(1)
Approach to treatment
331(5)
Recent and upcoming innovations
336(2)
Diagnostic imaging
336(1)
Pipeline treatments
337(1)
Summary
338(1)
Clinics care points
339(6)
Disclosure
339(6)
Update on the Classification and Management of Corneal Dystrophies
Vivian L. Qin
Devin Cohen
Tomas Andersen
Stephen E. Orlin
Introduction
345(2)
Significance/in-depth analysis
347(11)
Epithelial and Subepithelial Dystrophies
347(2)
Epithelial-Stromal TGFB1 dystrophies
349(4)
Stromal Dystrophies
353(3)
Endothelial Dystrophies
356(2)
Relevance and future avenues
358(3)
Summary
361(2)
Clinics care points
363(1)
Disclosure
363(4)
Surgical Management of the Aphakic Eye
Tianyu Liu
Brian J. Nguyen
Samantha L. Marek
Stephen E. Orlin
Introduction
367(1)
Significance and in-depth analysis of the topic
368(8)
Epikeratophakia
368(1)
Anterior chamber intraocular lenses
368(1)
Iris-fixated intraocular lenses
369(1)
Sulcus placement of intraocular lenses
370(2)
Sutured scleral-fixated intraocular lenses
372(2)
Sutureless scleral-fixated intraocular lenses
374(2)
Current relevance and future avenues
376(3)
Minimizing suture erosion with scleral pockets and Z-sutures
376(2)
Modifications of the Yamane sutureless fixation technique
378(1)
Correction of pediatric aphakia
378(1)
Summary
379(1)
Clinics care points
380(3)
Disclosure
380(3)
Oculoplastics
Teprotumumab: A Major Advance in the Treatment of Thyroid Eye Disease Management
Caroline Y. Yu
Jamie A. Keen
Erin M. Shriver
Introduction 383(18)
Pathophysiology of thyroid eye disease: the role of insulin-like growth factor 1 receptor
385(1)
Treatment landscape for thyroid eye disease--anti-inflammatory therapies
385(2)
Teprotumumab: mechanism of action
387(1)
Safety profile of teprotumumab
387(1)
Clinical effect of teprotumumab
388(2)
Clinical applications of teprotumumab: future avenues
390(5)
Clinics care points
395(1)
Disclosure
396(5)
Diagnosis and Management of Irritated Eyelids
Christine Ryu
Rao V. Chundury
Introduction
401(1)
Significance
402(17)
Blepharitis
402(1)
Immunologic
403(10)
Inflammatory
413(1)
Infectious
414(1)
Neoplastic
414(5)
Present relevance and future avenues
419(6)
Blepharitis
419(2)
Immunologic
421(1)
Inflammatory
421(3)
Infectious
424(1)
Neoplastic
424(1)
Summary
425(2)
Clinics care points
427(6)
Disclosure
428(5)
Uveitis
Uveitic Glaucoma
Erick Rivera-Grana
Stephanie M. Llop
Introduction
433(1)
Significance
434(6)
Pathogenesis
434(1)
Signs and symptoms
435(1)
Uveitis etiologies associated with uveitic glaucoma
436(4)
Present relevance and future directions to consider or investigate
440(5)
Standard treatment approaches
440(2)
Treatments apart from well-known intraocular pressure medications and filtering surgery
442(3)
Summary
445(1)
Clinics care points
446
Disclosure
446
Solo Private Practice Journey
Priya Kalyam
Introduction
i
A step forward
i
Opening the practice
ii
Day-to-day life
iii
Things I wish I focused on during residency
iv
Summary
iv
Disclosure
iv