| Contributors |
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ix | |
| Preface |
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xvi | |
| Acknowledgments |
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xviii | |
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Section 1 Basic Principles |
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1 Intrauterine growth and development |
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3 | (16) |
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2 Maternal physiological adaptations to pregnancy |
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19 | (6) |
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3 Placental respiratory gas exchange |
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25 | (7) |
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32 | (7) |
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5 Fetal responses to hypoxia |
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39 | (14) |
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6 Pharmacokinetics in pregnancy |
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53 | (10) |
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7 The first few breaths: normal transition from intra- to extra-uterine life |
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63 | (12) |
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Section 2 Endpoint Variables: Assessments of Fetal Wellbeing and Neonatal Outcome |
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8 Validity of endpoint measurement |
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75 | (14) |
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Section 2.1 Antenatal and Intrapartum Assessment of the Fetus |
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9 Imaging of the fetus and the uteroplacental blood supply: ultrasound |
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89 | (8) |
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10 Imaging of the fetus and the uteroplacental blood supply: MRI |
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97 | (7) |
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11 Fetal heart rate monitoring |
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104 | (10) |
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12 Fetal acid-base monitoring |
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114 | (9) |
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123 | (6) |
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14 Neonatal assessment and prediction of neonatal outcome |
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129 | (12) |
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Section 3 Interventions: Anesthesia, Analgesia, and Their Effects on the Fetus |
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15 Environmental exposure to anesthetic agents |
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141 | (6) |
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16 Anesthesia and analgesia for assisted reproduction techniques and other procedures during the first trimester |
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147 | (9) |
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17 The effect of anesthetic drugs on the developing fetus: considerations in non-obstetric surgery |
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156 | (9) |
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18 Substance abuse and pregnancy |
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165 | (8) |
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19 Intrauterine fetal procedures for congenital anomalies |
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173 | (10) |
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183 | (9) |
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21 Mechanisms and consequences of anesthetic-induced neuroapoptosis in the developing brain |
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192 | (8) |
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22 Relevance to clinical anesthesia of anesthetic-induced neurotoxicity in developing animals |
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200 | (10) |
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23 External cephalic version |
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210 | (7) |
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Section 3.1 Anesthesia for Cesarean Delivery |
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24 Effects on the fetus of general versus regional anesthesia |
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217 | (18) |
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25 Anesthesia for cesarean delivery: effects on the fetus of maternal blood pressure control |
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235 | (9) |
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26 Effects on the fetus of maternal oxygen administration |
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244 | (7) |
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27 Effects on the fetus of maternal position during cesarean delivery |
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251 | (12) |
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Section 3.2 Analgesia for Labor |
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28 Effects on the fetus of systemic vs. neuraxial analgesia |
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263 | (7) |
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29 The effects on the fetus of early versus late regional analgesia |
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270 | (7) |
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30 Regional analgesia, maternal fever, and its effect on the fetus and neonate |
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277 | (8) |
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31 Effects on the fetus of major maternal anesthetic complications |
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285 | (12) |
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Section 4 Confounding Variables: The Compromised Fetus, the Compromised Mother |
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297 | (6) |
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33 Preeclampsia: the compromised fetus, the compromised mother |
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303 | (12) |
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315 | (12) |
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Section 5 Trauma and Resuscitation |
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327 | (8) |
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36 Maternal resuscitation and perimortem cesarean delivery |
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335 | (10) |
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37 Intrauterine fetal resuscitation |
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345 | (7) |
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38 Neonatal resuscitation and immediate neonatal emergencies |
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352 | (13) |
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Section 6 Medicine, Ethics, and the Law |
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39 Fetal beneficence and maternal autonomy: ethics and the law |
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365 | (9) |
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40 Maternal-fetal research in pregnancy |
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374 | (7) |
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| Index |
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381 | |