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E-raamat: Basic Methods Handbook for Clinical Orthopaedic Research: A Practical Guide and Case Based Research Approach

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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 01-Feb-2019
  • Kirjastus: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • Keel: eng
  • ISBN-13: 9783662582541
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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 01-Feb-2019
  • Kirjastus: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • Keel: eng
  • ISBN-13: 9783662582541

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This book is designed to meet the needs of both novice and senior researchers in Orthopaedics by providing the essential, clinically relevant knowledge on research methodology that is sometimes overlooked during training. Readers will find a wealth of easy-to-understand information on all relevant aspects, from protocol design, the fundamentals of statistics, and the use of computer-based tools through to the performance of clinical studies with different levels of evidence, multicenter studies, systematic reviews, meta-analyses, and economic health care studies. A key feature is a series of typical case examples that will facilitate use of the volume as a handbook for most common research approaches and study types. Younger researchers will also appreciate the guidance on preparation of abstracts, poster and paper presentations, grant applications, and publications. The authors are internationally renowned orthopaedic surgeons with extensive research experience and the book is published in collaboration with ISAKOS.

Part I Evidence Based Medicine in Orthopaedics
1 What Is Evidence-Based Medicine?
3(8)
Eleonor Svantesson
Eric Hamrin Senorski
Jon Karlsson
Olufemi R. Ayeni
Kristian Samuelsson
2 What Is the Hierarchy of Clinical Evidence?
11(12)
Vishal S. Desai
Christopher L. Camp
Aaron J. Krych
3 Bias and Confounding
23(10)
Naomi Roselaar
Magaly Iniguez Cuadra
Stephen Lyman
4 Ethical Consideration in Orthopedic Research
33(10)
Jason L. Koh
Diego Villacis
5 Conflict of Interest
43(6)
Michael Hantes
Apostolos Fyllos
6 Ethics in Clinical Research
49(8)
Naomi Roselaar
Niv Marom
Robert G. Marx
Part II How to Get Started with Clinical Research?
7 How to Get Started: From Idea to Research Question
57(8)
Lachlan M. Batty
Timothy Lording
Eugene T. Ek
8 How to Write a Study Protocol
65(10)
Lukas B. Moser
Michael T. Hirschmann
9 The Ethical Approval Process
75(8)
Karren Takamura
Frank Petrigliano
10 How to Assess Patient's Outcome?
83(6)
Yuichi Hoshino
Alfonso Barnechea
11 Basics of Outcome Assessment in Clinical Research
89(8)
Monique C. Chambers
Sarah M. Tepe
Lorraine A. T. Boakye
MaCalus V. Hogan
12 Types of Scoring Instruments Available
97(14)
Jose F. Vega
Kurt P. Spindler
13 Health Measurement Development and Interpretation
111(10)
Andrew Firth
Dianne Bryant
Jacques Menetrey
Alan Getgood
14 How to Document a Clinical Study and Avoid Common Mistakes in Study Conduct?
121(12)
Caroline Mouton
Laura De Girolamo
Daniel Theisen
Romain Seil
15 Framework for Selecting Clinical Outcomes for Clinical Trials
133(10)
Adam J. Popchak
Andrew D. Lynch
James J. Irrgang
16 Advances in Measuring Patient-Reported Outcomes: Use of Item Response Theory and Computer Adaptive Tests
143(10)
Andrew D. Lynch
Adam J. Popchak
James J. Irrgang
Part III Basics in Statistics: Statistics Made Simple!
17 Common Statistical Tests
153(10)
Stephan Bodkin
Joe Hart
Brian C. Werner
18 The Nature of Data
163(8)
Clair Smith
19 Does No Difference Really Mean No Difference?
171(14)
Carola F. van Eck
Marcio Bottene Villa Albers
Andrew J. Sheean
Freddie H. Fu
20 Power and Sample Size
185(8)
Stephen Lyman
21 Visualizing Data
193(16)
Stephen Lyman
Naomi Roselaar
Chisa Hidaka
Part IV Basic Toolbox for the Young Clinical Researcher
22 How to Prepare an Abstract
209(10)
Elmar Herbst
Brian Forsythe
Avinesh Agarwalla
Sebastian Kopf
23 How to Make a Good Poster Presentation
219(8)
Baris Kocaoglu
Paulo Henrique Araujo
Carola Francisca van Eck
24 How to Prepare a Paper Presentation?
227(8)
Timothy Lording
Jacques Menetrey
25 How to Write a Clinical Paper
235(8)
Brendan Coleman
26 How to Write a Book
Chapter
243(6)
Thomas R. Pfeiffer
Daniel Guenther
27 How to Write a Winning Clinical Research Proposal?
249(6)
Christian Lattermann
Janey D. Whalen
28 How to Review a Clinical Research Paper?
255(10)
Neel K. Patel
Marco Yeung
Kanto Nagai
Volker Musahl
Part V How to Perform a Clinical Study: A Case Based Approach
29 Level 1 Evidence: A Prospective Randomized Controlled Study
265(20)
Seper Ekhtiari
Raman Mundi
Vickas Khanna
Mohit Bhandari
30 Level 1 Evidence: Long-Term Clinical Results
285(4)
Daisuke Araki
Ryosuke Kuroda
31 Level 2 Evidence: Prospective Cohort Study
289(6)
Naomi Roselaar
Niv Marom
Robert G. Marx
32 Level III Evidence: A Case-Control Study
295(6)
Andrew D. Lynch
Adam J. Popchak
James J. Irrgang
33 Level 4 Evidence: Clinical Case Series
301(6)
Mitchell I. Kennedy
Robert F. LaPrade
34 How to Perform a Clinical Study: Level 4 Evidence---Case Report
307(6)
Andrew J. Sheean
Gregory V. Gasbarro
Nasef M. N. Abedelatif
Volker Musahl
35 Level 5: Evidence
313(10)
Sean Mc Auliffe
Pieter D'Hooghe
Part VI How to Perform a Review Article?
36 Type of Review and How to Get Started
323(8)
Matthew Skelly
Andrew Duong
Nicole Simunovic
Olufemi R. Ayeni
Part VII How to Perform a Systematic Review or Meta-analysis?
37 What Is the Difference Between a Systematic Review and a Meta-analysis?
331(12)
Shakib Akhter
Thierry Pauyo
Moin Khan
38 Reliability Studies and Surveys
343(16)
Kelsey L. Wise
Brandon J. Kelly
Michael L. Knudsen
Jeffrey A. Macalena
39 Registries
359(14)
R. Kyle Martin
Andreas Persson
Havard Visnes
Lars Engebretsen
Part VIII How to Perform an Economic Health Care Study?
40 How to Perform an Economic Healthcare Study
373(10)
Jonathan Edgington
Xander Kerman
Lewis Shi
Jason L. Koh
Part IX Multi-Center Study: How to Pull It Off?
41 Conducting Multicenter Cohort Studies: Lessons from MOON
383(8)
Jose F. Vega
Kurt P. Spindler
42 MARS: The Why and How of It
391(12)
Rick W. Wright
Amanda K. Haas
Laura J. Huston
43 Multicenter Study: How to Pull It Off? The PIVOT Trial
403(12)
Eleonor Svantesson
Eric Hamrin Senorski
Alicia Oostdyk
Yuichi Hoshino
Kristian Samuelsson
Volker Musahl
44 Conducting a Multicenter Trial: Learning from the JUPITER (Justifying Patellar Instability Treatment by Early Results) Experience
415(12)
Jason L. Koh
Shital Parikh
Beth Shubin Stein
45 How to Organise an International Register in Compliance with the European GDPR: Walking in the Footsteps of the PAMI Project (Paediatric ACL Monitoring Initiative)
427(10)
Daniel Theisen
Havard Moksnes
Cyrille Hardy
Lars Engebretsen
Romain Seil
Part X Helpful Further Information
46 Common Scales and Checklists in Sports Medicine Research
437(34)
Alberto Grassi
Luca Macchiarola
Marco Casali
Ilaria Cucurnia
Stefano Zaffagnini
47 A Practical Guide to Writing (and Understanding) a Scientific Paper: Meta-Analyses
471(28)
Alberto Grassi
Riccardo Compagnoni
Kristian Samuelsson
Pietro Randelli
Corrado Bait
Stefano Zaffagnini
48 A Practical Guide to Writing (and Understanding) a Scientific Paper: Clinical Studies
499(8)
Riccardo Compagnoni
Alberto Grassi
Stefano Zaffagnini
Corrado Bait
Kristian Samuelsson
Alessandra Menon
Pietro Randelli
49 Reporting Complications in Orthopaedic Trials
507(8)
S. Goldhahn
Norimasa Nakamura
J. Goldhahn
50 Understanding and Addressing Regulatory Concerns in Research
515(18)
Jason L. Koh
Denise Gottfried
Daniel R. Lee
Sandra Navarrete
51 What Is Needed to Make Collaboration Work?
533(4)
Richard E. Debski
Gerald A. Ferrer
52 A Clinical Practice Guideline
537(14)
Aleksei Dingel
Jay son Murray
James Carey
Deborah Cummins
Kevin Shea
53 How to Navigate a Scientific Meeting and Make It Worthwhile? A Guide for Young Orthopedic Surgeons
551(10)
Darren de Sa
Jayson Lian
Conor I. Murphy
Ravi Vaswani
Volker Musahl
54 How to Write a Scientific Article
561(18)
Lukas B. Moser
Michael T. Hirschmann
55 Common Mistakes in Manuscript Writing and How to Avoid Them
579
Eleonor Svantesson
Eric Hamrin Senorski
Kristian Samuelsson
Jon Karlsson
Volker Musahl, MD, is Associate Professor of Orthopaedic Surgery at the University of Pittsburgh School of Medicine, Associate Professor of Bioengineering at the University of Pittsburgh's Swanson School of Engineering, Program Director of the Sports Medicine fellowship program, and Medical Director of the UPMC Center for Sports Medicine. Dr. Musahl has received various honors and awards and in 2015 was appointed Assistant Editor-in-Chief of Knee Surgery, Sports Traumatology, Arthroscopy (KSSTA). His research interests include knee and shoulder biomechanics. 

Jon Karlsson, MD, PhD, is Professor of Orthopaedics and Sports Traumatology at Sahlgrenska Academy, Gothenburg University, Sweden, where he is a Senior Consultant and Academic Head of the Orthopaedic Department. He is the editor or author of more than 300 papers and 30 textbooks in Orthopaedics and Sports Traumatology. He has held important positions in both ESSKA and ISAKOS and is currently Editor-in-Chief of Knee Surgery, Sports Traumatology, Arthroscopy (KSSTA). 

Michael T. Hirschmann, MD, is Leading Consultant in Head and Knee Surgery, Department of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland, Switzerland. He was awarded his Habilitation venia docendi from the University of Basel in 2012. Dr. Hirschmann is a member of the Executive Committee of the Gesellschaft für Arthroskopie und Gelenkchirurgie and Secretary General of European Knee Associates. He is a member of the editorial boards of various journals, including KSSTA and World Journal of Orthopedics. 

Olufemi R. Ayeni, MD, MSc, FRCSC, is Associate Professor in the Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada. He is also Director of MacSports, Division of Orthopaedic Surgery, McMaster University. Dr. Ayeni is an ISAKOS Scientific Committee Member. He acts as a reviewer for a number of leading journals in Orthopaedics and Sports Medicine and is lead or co-author of over 150 peer-reviewed journal articles. 

Robert G. Marx, MS, MSc, is Attending Orthopaedic Surgeon at the Hospital for Special Surgery, Weill Cornell Medical College, New York, where he is Professor of Orthopaedic Surgery and Professor of Public Health. He is also Director of the Foster Center for Clinical Outcome Research, Hospital for Special Surgery. He is a former member of the Board of Directors of ISAKOS and has served as Chair of the ISAKOS Scientific Advisory Committee. Dr. Marx is the author of four books and 210 peer-reviewed articles. 

Jason Lee Koh, MD, MBA, is Chairman of the Department of Orthopaedic Surgery and Clinical Director of the Orthopaedic Institute at NorthShore University HealthSystem, Chicago. He is also Clinical Professor of Surgery at University of Chicago Pritzker School of Medicine. In 2012 he received the prestigious Charles Neer Award from the American Shoulder and Elbow Society. Dr. Koh has sat on numerous committees and is a member of the Board of Councilors of the American Academy of Orthopaedic Surgery. 





Norimasa Nakamura, MD, PhD, is an orthopaedic surgeon and Professor at the Institute for Medical Science in Sports, Osaka Health Science University, Osaka City, Japan. Dr. Nakamura is a Fellow of the Royal College of Surgeons (FRCS) (England). He is President of the International Cartilage Repair Society (ICRS) and a former chair of the Scientific Committee of ISAKOS. He is a member of the editorial boards of various leading journals in the field of Orthopaedics and author of more than 120 peer-reviewed papers.