| Contributors |
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xiii | |
| Preface |
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xvii | |
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Section I Theories and concepts of big data analytics in healthcare |
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1 Big data analytics in healthcare: theory, tools, techniques and its applications |
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3 | (2) |
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3 | (1) |
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4 | (1) |
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4 | (1) |
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1.4 Other factors influencing in big data |
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4 | (1) |
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2 Challenges in big data analytics |
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5 | (1) |
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2.1 Management of big data |
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5 | (1) |
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2.2 Security and privacy concerns |
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5 | (1) |
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6 | (1) |
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3 Data analytics life cycle |
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6 | (1) |
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6 | (1) |
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3.2 Big data acquisition in healthcare |
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7 | (1) |
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4 Data analytics during the Covid-19 pandemic |
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7 | (2) |
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5 Big data tools in healthcare |
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9 | (1) |
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5.1 Big data management and analysis |
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9 | (1) |
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10 | (3) |
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10 | (1) |
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11 | (2) |
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2 Driving impact through big data utilization and analytics in the context of a Learning Health System |
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13 | (1) |
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2 What matters for healthcare? |
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13 | (1) |
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3 Global strategies for impact on health |
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14 | (1) |
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14 | (1) |
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5 Applying big data--precision medicine |
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15 | (1) |
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6 Learning Health System--a paradigm for the future? |
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15 | (2) |
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7 Driving big data utilization in an LHS |
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17 | (2) |
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19 | (1) |
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19 | (4) |
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20 | (1) |
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20 | (3) |
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3 Classification of medical big data: a review of systematic analysis of medical big data in real-time setup |
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Katpadi Varadarajan Arulalan |
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23 | (1) |
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24 | (3) |
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2.1 Attributes of big data |
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25 | (1) |
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2.2 Core big data analysis strategies |
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25 | (2) |
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3 Accountancy of big data analytics in health care domains |
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27 | (1) |
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3.1 Hospital and health hubs |
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27 | (1) |
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3.2 Malignancy detection using big data analytics |
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27 | (1) |
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28 | (1) |
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28 | (1) |
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28 | (1) |
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3.6 Evolution of new medicines and practices in healthcare |
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28 | (1) |
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4 Machine learning based on big data analytics in real time: autism disease diagnosis |
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28 | (2) |
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5 Open source tools: cloud resources for health care management |
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30 | (1) |
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30 | (1) |
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31 | (2) |
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32 | (1) |
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4 Towards big data framework in government public open data (GPOD) for health |
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Nur Hidayah Ilham Ahmad Azri |
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33 | (1) |
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34 | (2) |
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36 | (1) |
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37 | (6) |
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5 Contribution, limitation, and discussion |
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43 | (1) |
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44 | (5) |
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44 | (1) |
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45 | (4) |
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Section II Big medical data: Techniques, managements, and applications |
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5 Big data analytics techniques for healthcare |
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49 | (1) |
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50 | (2) |
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50 | (1) |
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50 | (1) |
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51 | (1) |
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51 | (1) |
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52 | (1) |
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52 | (1) |
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3 Characteristics of big data in healthcare |
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52 | (1) |
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52 | (1) |
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52 | (1) |
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53 | (1) |
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53 | (1) |
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53 | (1) |
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53 | (1) |
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4 Key elements of big data analysis |
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53 | (3) |
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54 | (1) |
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54 | (2) |
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56 | (1) |
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56 | (1) |
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5 Big data analytical tools used in healthcare |
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56 | (5) |
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5.1 Hadoop distribution file system |
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56 | (1) |
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57 | (1) |
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58 | (1) |
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59 | (1) |
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59 | (1) |
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60 | (1) |
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61 | (2) |
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61 | (2) |
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6 Big data analytics in precision medicine |
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63 | (1) |
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63 | (1) |
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64 | (1) |
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2.2 Electronic health record data |
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64 | (1) |
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3 Challenges associated with big data |
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64 | (1) |
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64 | (1) |
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65 | (1) |
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3.3 Data quality problems |
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65 | (1) |
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3.4 Frequency of collecting diverse data |
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65 | (1) |
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4 Machine learning techniques for big data analytics |
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65 | (1) |
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66 | (3) |
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5.1 Big data analytics in omics data |
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66 | (2) |
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5.2 Big data analytics in EHR data |
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68 | (1) |
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5.3 Enablers for big medical data analytics |
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69 | (1) |
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69 | (2) |
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6.1 Disease subtyping and biomarker discovery |
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69 | (1) |
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70 | (1) |
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6.3 Integrating omics data into EHR |
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71 | (1) |
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71 | (2) |
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72 | (1) |
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7 Recent advances in processing, interpreting, and managing biological data for therapeutic intervention of human infectious disease |
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73 | (1) |
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74 | (1) |
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1.1 Need of big data in therapeutic intervention |
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75 | (1) |
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2 Biological data capturing and processing |
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75 | (2) |
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2.1 Architectural framework |
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75 | (1) |
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76 | (1) |
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2.3 Maintenance of threshold quality of data |
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76 | (1) |
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3 Interpretation of processed clinical data |
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77 | (1) |
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77 | (1) |
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3.2 Quantitative approach |
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78 | (1) |
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4 Patients' data management for digital therapeutics |
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78 | (1) |
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5 Advantages and limitations |
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79 | (1) |
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6 Conclusion and future direction |
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80 | (3) |
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80 | (1) |
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80 | (3) |
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8 Big data analytics for health: a comprehensive review of techniques and applications |
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83 | (1) |
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84 | (4) |
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84 | (1) |
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2.2 Dimensions of big data in health |
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84 | (1) |
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2.3 Big data--based research in health |
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85 | (1) |
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2.4 Big data analytics applications for health |
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85 | (3) |
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88 | (1) |
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3.1 Opportunities and challenges |
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88 | (1) |
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89 | (6) |
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90 | (1) |
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90 | (5) |
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Section III Diagnosis and treatment: Big data analytical techniques, datasets, life cycles, managements, and applications for diagnosis and treatment |
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9 Recent applications of data mining in medical diagnosis and prediction |
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95 | (1) |
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2 Big data and the health sector |
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96 | (2) |
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3 A machine learning medical diagnosis model based on patients' complaints |
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98 | (1) |
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4 An early prediction and diagnosis of sepsis in intensive care units |
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98 | (2) |
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5 A machine learning approach to predict creatine kinase test results |
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100 | (2) |
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101 | (1) |
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6 Use of artificial intelligence in the prediction of malignant potential of gastric gastrointestinal stromal tumors |
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102 | (2) |
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7 Weekly emotional changes amidst Covid-19: Turkish experience |
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104 | (3) |
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107 | (4) |
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107 | (4) |
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10 Big medical data analytics for diagnosis |
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111 | (3) |
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111 | (1) |
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112 | (1) |
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1.3 Impact of big medical data on the healthcare system |
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112 | (1) |
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1.4 Digitized big medical data analytical applications for the health industry |
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112 | (2) |
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2 Big medical data analytics in disease diagnosis |
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114 | (6) |
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114 | (1) |
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115 | (2) |
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117 | (1) |
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118 | (2) |
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3 Big medical data analytics tools/algorithms |
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120 | (1) |
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3.1 Machine learning on big medical data analysis for diagnosis |
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120 | (1) |
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3.2 Data mining in big medical data analytics |
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120 | (1) |
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3.3 The Internet of Things and disease prediction |
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121 | (1) |
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121 | (1) |
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122 | (1) |
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122 | (3) |
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122 | (3) |
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11 Big data analytics and radiomics to discover diagnostics on different cancer types |
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125 | (1) |
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125 | (1) |
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3 The methodology of radiomics |
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126 | (3) |
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127 | (1) |
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127 | (1) |
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127 | (1) |
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127 | (2) |
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4 The applications of radiomics on several kinds of cancer types |
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129 | (1) |
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130 | (2) |
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130 | (1) |
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131 | (1) |
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131 | (1) |
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5.4 The components of big data |
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131 | (1) |
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132 | (2) |
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7 The similarities and differences of radiomics and big data analytics |
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134 | (1) |
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8 The challenges of radiomics and big data analytics |
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134 | (1) |
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9 The relationship between radiomics and big data analytics |
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135 | (1) |
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136 | (1) |
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136 | (3) |
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136 | (3) |
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12 Big medical data, cloud computing, and artificial intelligence for improving diagnosis in healthcare |
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139 | (1) |
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2 Retrieving patient data from medical apps |
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140 | (2) |
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2.1 Medical apps for cutaneous disorders |
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140 | (1) |
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2.2 Medical apps for cardiovascular diseases |
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141 | (1) |
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2.3 Medical apps for visual and cognitive disorders |
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142 | (1) |
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2.4 New methods in apps for testing blood pressure and blood glucose levels |
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142 | (1) |
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3 Collecting patient data into cloud-based big data repositories |
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142 | (2) |
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3.1 Big data repositories in healthcare |
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142 | (1) |
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3.2 Management and analysis of big data in healthcare |
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143 | (1) |
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3.3 Commercial platforms for healthcare data analytics |
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144 | (1) |
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4 Using artificial intelligence techniques for improving diagnosis |
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144 | (3) |
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4.1 Clinical Information Systems and clinical decision support systems |
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144 | (1) |
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4.2 Al methods used in healthcare |
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145 | (2) |
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147 | (6) |
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148 | (5) |
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Section IV Prediction: Big data analytical techniques, datasets, life cycles, managements, and applications for prediction |
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13 Use of artificial intelligence for predicting infectious disease |
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153 | (1) |
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2 Mathematical modeling of infectious diseases and their development |
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153 | (5) |
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153 | (3) |
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156 | (2) |
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3 Predicting infectious diseases using artificial intelligence |
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158 | (3) |
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158 | (1) |
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159 | (2) |
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161 | (4) |
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162 | (3) |
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14 Hospital data analytics system for tracking and predicting obese patients' lifestyle habits |
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165 | (1) |
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166 | (1) |
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2.1 Existing habit-based healthcare systems with analytical features |
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166 | (1) |
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2.2 Big data and predictive analytics in healthcare |
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166 | (1) |
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2.3 Big data and Clinical Decision Support Systems |
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166 | (1) |
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3 Development methodology |
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167 | (1) |
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4 System design and implementation |
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168 | (3) |
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4.1 System modules and use case diagram |
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168 | (2) |
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4.2 System architecture design and predictive analytics |
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170 | (1) |
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4.3 Implementation strategy |
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171 | (1) |
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171 | (1) |
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5 Data analytics, results, and user interface |
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171 | (5) |
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171 | (2) |
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5.2 Predictive analytics using machine learning |
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173 | (3) |
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5.3 User interface design |
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176 | (1) |
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6 Discussion and conclusion |
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176 | (3) |
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178 | (1) |
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178 | (1) |
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15 Predictions on diabetic patient datasets using big data analytics and machine learning techniques |
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179 | (1) |
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1.1 Challenges of healthcare data |
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180 | (1) |
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2 Big data analytics using mapreduce, Pig, Hive, and Spark |
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180 | (3) |
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2.1 Hadoop MapReduce framework |
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181 | (1) |
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181 | (1) |
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181 | (1) |
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182 | (1) |
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183 | (14) |
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3.1 Big data and machine learning techniques for healthcare |
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189 | (8) |
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197 | (4) |
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198 | (3) |
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16 Skin cancer prediction using big data analytics and Al techniques |
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201 | (3) |
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1.1 Dimensions of big data |
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201 | (2) |
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203 | (1) |
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203 | (1) |
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1.4 Platforms of big data analytics |
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204 | (1) |
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204 | (1) |
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204 | (1) |
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205 | (2) |
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207 | (3) |
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208 | (1) |
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208 | (1) |
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5.3 Techniques/models/algorithms |
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208 | (1) |
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208 | (1) |
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5.5 Support vector machine |
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208 | (1) |
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209 | (1) |
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209 | (1) |
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209 | (1) |
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209 | (1) |
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210 | (1) |
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6 Data visualization and analysis |
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210 | (2) |
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212 | (4) |
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7.1 Model implementation of combination of logistic regression, support vector machine, and gradient boosting |
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212 | (1) |
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7.2 Model implementation using VGG19 architecture |
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213 | (1) |
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7.3 Model implementation of lnceptionResNetV2 |
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214 | (1) |
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7.4 Model implementation of MobileNet SSD |
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214 | (1) |
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7.5 Model implementation MelConvo2D |
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215 | (1) |
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216 | (5) |
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217 | (4) |
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Section V Big medical fake news analytics for preventing medical misinformation and myths |
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17 COVID-19 fake news analytics from social media using topic modeling and clustering |
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221 | (1) |
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2 Background and related work |
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221 | (1) |
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2.1 Misinformation and fake news |
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222 | (1) |
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2.2 Related studies of misinformation and medical fake news on social media related to COVID-19 |
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222 | (1) |
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222 | (1) |
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222 | (1) |
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223 | (1) |
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223 | (1) |
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4 Data ana Vysis and results (COVID-19 news classification) |
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223 | (7) |
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4.1 COVID-19 news dataset |
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223 | (1) |
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4.2 Data cleaning and data preprocessing |
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224 | (1) |
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4.3 Initial analysis and data exploration |
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224 | (3) |
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227 | (3) |
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230 | (3) |
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231 | (1) |
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231 | (2) |
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18 Big medical data mining system (BigMed) for the detection and classification of COVID-19 misinformation |
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233 | (1) |
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2 Background and related works |
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233 | (1) |
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3 Development methodology |
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234 | (1) |
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4 System design and implementation |
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234 | (5) |
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4.1 System architecture and module design |
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234 | (2) |
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236 | (1) |
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4.3 System interface design |
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236 | (2) |
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4.4 Implementation strategy |
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238 | (1) |
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5 Data analytics and user interface |
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239 | (1) |
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5.1 Dataset and data preprocessing |
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239 | (1) |
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5.2 News detection and classification |
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239 | (1) |
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239 | (1) |
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6 System testing and evaluation |
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240 | (3) |
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240 | (3) |
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243 | (4) |
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244 | (1) |
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244 | (3) |
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Section VI Challenges and future of big data in healthcare |
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19 Privacy security risks of big data processing in healthcare |
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247 | (1) |
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247 | (1) |
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247 | (1) |
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2.2 Privacy issues of HBD |
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248 | (1) |
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2.3 Solution of the privacy problem of HBD |
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248 | (1) |
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248 | (7) |
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3.1 Big data analysis in China's healthcare sector |
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248 | (1) |
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3.2 Key technologies of HBD mining |
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248 | (2) |
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3.3 Establishment of indicator system for privacy and security risk assessment of HBD |
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250 | (1) |
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3.4 Assessment model for privacy security risk |
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251 | (4) |
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255 | (7) |
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4.1 Analysis on the development status of China's medical and healthcare field |
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255 | (1) |
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4.2 Analysis of medical and healthcare costs of major diseases in China |
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256 | (1) |
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4.3 Testing of privacy and security risk assessment model for HBD in cloud environment |
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257 | (3) |
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4.4 Application of parallel random forest algorithm in hospital intelligent guidance |
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260 | (2) |
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262 | (3) |
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262 | (1) |
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262 | (3) |
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20 Opportunities and challenges in healthcare with the management of big biomedical data |
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265 | (1) |
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2 Biomedical data types and role of machine learning |
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266 | (3) |
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2.1 Electronic health records |
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266 | (1) |
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267 | (2) |
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3 Current big data challenges in healthcare |
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269 | (3) |
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3.1 Big data and healthcare |
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269 | (2) |
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3.2 Big data challenges in healthcare |
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271 | (1) |
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4 Healthcare data management and its limitations |
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272 | (1) |
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4.1 Data interoperability |
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272 | (1) |
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272 | (1) |
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273 | (1) |
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273 | (1) |
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273 | (4) |
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273 | (4) |
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21 Future direction for healthcare based on big data analytics |
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277 | (1) |
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277 | (3) |
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2.1 Leadership conceptual framework |
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277 | (1) |
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2.2 Big data analytics and Al in the health sector |
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278 | (2) |
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3 Empirical methodological approach |
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280 | (2) |
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281 | (1) |
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282 | (2) |
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5 Implications and future research |
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284 | (1) |
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5.1 Theoretical implications of the study findings |
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284 | (1) |
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284 | (1) |
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5.3 Future research avenues |
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284 | (1) |
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284 | (7) |
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285 | (1) |
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285 | (1) |
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286 | (5) |
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Section VII Case studies of big data in healthcare arena |
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22 Big data in orthopedics: between hypes and hopes |
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291 | (2) |
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2 Roles and applications of epidemiological big data in current orthopedics research |
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293 | (2) |
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3 Roles and applications of molecular big data in current orthopedics research |
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295 | (1) |
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4 Roles and applications of big data generated by imaging techniques and wearable technologies/smart sensors in current orthopedics research |
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295 | (1) |
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5 Roles and applications of infodemiological big data in current orthopedics research |
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296 | (1) |
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6 "Participatory orthopedics": integrating basic and translational orthopedics and citizen science |
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296 | (1) |
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7 Conclusions and future prospects |
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297 | (4) |
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297 | (4) |
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23 Predicting onset (type-2) of diabetes from medical records using binary class classification |
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301 | (1) |
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1.1 Background of the study |
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301 | (1) |
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1.2 Problem statement, objectives, and scope of the study |
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301 | (1) |
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301 | (3) |
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301 | (2) |
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303 | (1) |
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304 | (2) |
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304 | (1) |
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3.2 Brief description of algorithms used |
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304 | (1) |
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305 | (1) |
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305 | (1) |
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305 | (1) |
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306 | (5) |
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4.1 Classifier's performance based on of classified instance |
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306 | (1) |
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307 | (1) |
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307 | (1) |
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307 | (1) |
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308 | (1) |
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309 | (1) |
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4.7 Comparative analysis summary |
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310 | (1) |
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311 | (2) |
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311 | (2) |
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24 Screening programs incorporating big data analytics |
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1 Introduction: disease screening and screening programs |
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313 | (3) |
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1.1 Goals and measures for screening programs |
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313 | (1) |
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1.2 Measures and utility of a screening program |
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314 | (1) |
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1.3 Databases and training sets of screening programs |
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314 | (1) |
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1.4 Nationwide screening programs |
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314 | (2) |
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2 Evidence-based medicine for big data analytics--facilitated screening programs |
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316 | (3) |
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2.1 Principles of evidence-based medicine |
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316 | (1) |
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2.2 Gap between clinical research and best practices |
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317 | (1) |
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2.3 Hierarchy and levels of clinical evidence and information |
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318 | (1) |
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3 Screening programs incorporating big data analytics |
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319 | (3) |
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3.1 Cancer screening programs in the era of big data analytics |
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319 | (1) |
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3.2 Diabetes screening programs in the era of big data analytics |
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320 | (1) |
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3.3 Drug allergy screening in the era of big data analytics |
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321 | (1) |
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4 Challenges of big data--acilitated screening programs |
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322 | (2) |
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4.1 Acquisition of high-quality clinical data |
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322 | (1) |
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4.2 Overdiagnoses in big data--facilitated screening programs |
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322 | (1) |
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4.3 External validation with prospective studies |
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323 | (1) |
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4.4 Ensuring representativeness and mitigating bias |
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323 | (1) |
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5 Conclusions: toward next generation big data analytics--facilitated disease screening |
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324 | (5) |
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324 | (5) |
| Index |
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329 | |