Leading international scientists bring current and developing topics in sterol research together in Biochemistry and Function of Sterols
Leading international scientists bring current and developing topics in sterol research together in Biochemistry and Function of Sterols. The authors are experts in each major area of sterol research-medicine, biochemistry, chemistry, and agriculture. Each chapter features the current state of research as well as new and developing research topics. Throughout the volume the focus is on the major and expanding areas of sterol biochemistry and function of sterols in all classes or organisms. The broad scope of this work embraces many disciplines and will be of interest to a variety of researchers, students, and lay people. Professors will find Biochemistry and Function of Sterols an excellent choice as a textbook for courses on steroid, lipid, or plant biochemistry.
Chapter 1 Inhibitors of 2,3-Oxidosqualene Cyclase as Tools for Studying the Mechanism and Function of the Enzyme 1(22) Luigi Cattel Maurizio Ceruti
Chapter 2 Aromatase Inhibitors 23(32) J. ONeal Johnston
Chapter 3 Variability of Metabolism and Function of Sterols in Insects 55(10) James A. Svoboda
Chapter 4 Oxysterols and Apoptosis: Evidence for Gene Regulation Outside the Cholesterol Pathway 65(8) E. Brad Thompson Sylvette Ayala-Torres
Chapter 5 Tracing Steroid Synthesis in Plants 73(12) Henri W. Groeneveld
Chapter 6 Biochemistry and Molecular Biology of Sterol Synthesis in Saccharomyces cerevisiae 85(16) Norman D. Lees Martin Bard Donald R. Kirsch
Chapter 7 19-Noraldosterone 101(10) Yoshiyu Takeda
Chapter 8 Enzymology of Phytosterol Transformations 111(12) W. David Nes Mylavarapu Venkatramesh
Chapter 9 Isoprenoid Biosynthesis in Plants: Carbon Partitioning Within the Cytoplasmic Pathway 123(12) Jeffery D. Newman Joseph Chappell
Chapter 10 Mevalonate Biosynthesis in Plants 135(16) Thomas J. Bach Albert Boronat Narciso Campos Albert Ferrer Kai-Uwe Vollack
Chapter 11 Lanosterol Analogs: Dual-Action Inhibitors of Cholesterol Biosynthesis 151(18) Leah L. Frye Deborah A. Leonard
Chapter 12 Biochemistry and Function of Nematode Steroids 169(12) David J. Chitwood
Chapter 13 Occurrence, Biosynthesis, and Putative Role of Ecdysteriods in Plants 181(12) John H. Adler Robert J. Grebenok
Chapter 14 Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity by Side-Chain Oxysterols and Their Derivatives 193(8) Edward J. Parish Sarawanee C. Parish Shengrong Li
Chapter 15 Biological Effects of Brassinosteroids 201(20) Carme Brosa
Chapter 16 Vitamin D: A Hormonal Regulator of the cAMP Signaling Pathway 221(10) Jens P. Berg Egil Haug
Chapter 17 Protein Isoprenylation in Plants 231(14) Stephen K. Randall Dring N. Crowell
Chapter 18 Chemical Modulation of Activity in Steroidal Estrogens 245(12) Eduardo Palomino
Chapter 19 Use of Sterol Mutants as Probes for Sterol Functions in the Yeast, Saccharomyces cerevisiae 257(6) Leo W. Parks James H. Crowley Frank W. Leak Steven J. Smith Michele E. Tomeo
Chapter 20 Integration of the Metabolic Pathways of Steroids, Carotenoids, and Retinoids 263(6) Anthony M. Gawienowski Index 269
Edward J. Parish and W. David Nes
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