Surveys the biocomputing needs and objectives of genome projects as of the early 1990s, focusing on the mapping of human genes. Covering automated laboratory notebooks, nucleic acid sequence analysis, protein structure, and database activities, provides a grounding in genome-related informatics. Accessible to undergraduates in molecular biology and related fields. Annotation copyright Book News, Inc. Portland, Or.
The results of today's genome projects promise enormous medical and agricultural benefits and point to a new predictive approach to the conduct of future research in biology. Biocomputing: Informatics and Genome Projects represents a survey of the needs and objectives of genome projects as of the early 1990's. It provides the groundwork necessary to understand genome-related informatics, including computational and database storage objectives. The book covers four general areas: automated laboratory notebooks, nucleic acid sequence analysis, protein structure, and database activities.
D.W. Smith, Introduction.
S.P. Clark, G.A. Evans, and H.R. Garner, Informatics and Automation Used in
Physical Mapping of the Genome.
D.W. Smith, J. Jorgensen, J.P. Greenberg, J. Keller, J. Rogers, H.R. Garner,
and L.T. Eyck, Supercomputers, Parallel Processing, and Genome Projects.
S. Henikoff, Comparative Sequence Analysis: Finding Genes.
A.K. Knopka, Sequence and Codes: Fundamentals of Biomolecular Cryptology.
C. Wills, Phylogenetic Analysis and Molecular Evolution.
B.I. Cohen and F.E. Cohen, Predictions of Protein Secondary and Tertiary
Structure.
K. Yoshida, C.L. Smith, and R. Overbeek, A Primer on Rapid Prototyping of
Genomic Databases in Prolog.
D.W. Mount and B.R. Schatz, A Genomic Database of E. coli: Total Information
on a Given Organism.
A.R. Galper and D.L. Brutlag, Computational Simulations of Biological
Systems.
Index.
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