Preface |
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xv | |
Acknowledgments |
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xix | |
Abbreviations and Acronyms |
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xxi | |
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1 Introduction: What Is Biomedical Engineering? |
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1 | (36) |
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1 | (3) |
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1.2 Engineering in modem medicine |
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4 | (4) |
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1.3 What is biomedical engineering? |
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8 | (15) |
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1.4 Biomedical engineering in the future |
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23 | (3) |
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26 | (11) |
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Profiles In BME: THE Author, W. Mark Saltzman |
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28 | (9) |
Part 1. Molecular And Cellular Principles |
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2 Biomolecular Principles |
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37 | (57) |
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37 | (2) |
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2.2 Bonding between atoms and molecules |
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39 | (4) |
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2.3 Water: The medium of life |
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43 | (2) |
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2.4 Biochemical energetics |
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45 | (5) |
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50 | (8) |
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2.6 Macromolecules: Polymers of biological importance |
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58 | (14) |
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72 | (22) |
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Profiles In BME: Tiffanee Green Mackey |
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80 | (14) |
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3 Biomolecular Principles: Nucleic Acids |
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94 | (66) |
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94 | (5) |
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3.2 Overview: Genetics and inheritance |
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99 | (7) |
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3.3 Molecular basis of genetics |
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106 | (10) |
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3.4 The central dogma: Transcription and translation |
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116 | (7) |
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3.5 Control of gene expression |
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123 | (5) |
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3.6 Recombinant DNA technology |
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128 | (32) |
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Profiles In BME: Laura Liptai |
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143 | (17) |
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4 Biomolecular Principles: Proteins |
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160 | (30) |
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160 | (2) |
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162 | (9) |
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4.3 Modification and processing of polypeptides |
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171 | (4) |
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175 | (15) |
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Profiles In BME: Brenda K. Mann |
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182 | (8) |
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190 | (41) |
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190 | (2) |
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5.2 Cell structure and function |
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192 | (4) |
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196 | (2) |
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5.4 Molecules in the cell membrane |
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198 | (8) |
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206 | (4) |
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5.6 Cell differentiation and stem cells |
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210 | (3) |
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213 | (1) |
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5.8 Cell culture technology |
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214 | (17) |
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Profiles In BME: E.E. "Jack" Richards II |
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219 | (12) |
Part 2. Physiological Principles |
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6 Communication Systems in the Body |
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231 | (49) |
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231 | (6) |
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6.2 Signaling fundamentals |
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237 | (5) |
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242 | (9) |
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251 | (5) |
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6.5 The adaptive immune system |
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256 | (9) |
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6.6 Connections to biomedical engineering |
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265 | (15) |
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Profiles In BME: Douglas Lauffenburger |
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268 | (12) |
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7 Engineering Balances: Respiration and Digestion |
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280 | (61) |
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280 | (1) |
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7.2 Introduction to mass balances |
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281 | (14) |
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7.3 Respiratory physiology |
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295 | (18) |
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7.4 Digestion and metabolism |
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313 | (28) |
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331 | (10) |
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341 | (36) |
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341 | (1) |
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8.2 The circulating fluid |
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342 | (3) |
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345 | (16) |
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361 | (16) |
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Profiles In BME: Curtis G. Neason |
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368 | (9) |
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9 Removal of Molecules from the Body |
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377 | (36) |
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377 | (2) |
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9.2 Examples of elimination of molecules from the body |
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379 | (4) |
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9.3 Biotransformation and biliary excretion |
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383 | (2) |
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9.4 Elimination of molecules by the kidneys |
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385 | (28) |
Part 3. Biomedical Engineering |
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413 | (35) |
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413 | (2) |
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10.2 Mechanical properties of materials |
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415 | (9) |
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10.3 Mechanical properties of tissues and organs |
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424 | (9) |
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433 | (15) |
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Profiles In BME: Walt Baxter |
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438 | (10) |
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448 | (49) |
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448 | (3) |
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11.2 Overview of measurement systems |
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451 | (2) |
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453 | (10) |
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11.4 Instruments in medical practice |
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463 | (15) |
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11.5 Instruments in the research laboratory |
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478 | (4) |
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482 | (2) |
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11.7 Biomicroelectromechanical systems and lab-on-a-chip devices |
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484 | (13) |
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Profiles In BME: Bill Hawkins |
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488 | (9) |
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497 | (47) |
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497 | (4) |
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501 | (7) |
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508 | (5) |
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513 | (7) |
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520 | (4) |
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524 | (3) |
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12.7 Image processing and analysis |
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527 | (17) |
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Profiles In BME: Rebecca Richards-Kortum |
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535 | (9) |
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13 Biomolecular Engineering I: Biotechnology |
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544 | (44) |
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544 | (2) |
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546 | (13) |
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559 | (8) |
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567 | (7) |
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13.5 Other areas of biomolecular engineering |
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574 | (14) |
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Profiles In BME: Robert Langer |
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577 | (11) |
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14 Biomolecular Engineering II: Engineering of Immunity |
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588 | (38) |
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588 | (2) |
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14.2 Antigens, Abs, and mAbs |
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590 | (2) |
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592 | (5) |
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14.4 How can specific Abs be manufactured? |
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597 | (3) |
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14.5 Clinical uses of Abs |
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600 | (3) |
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603 | (23) |
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Profiles In BME: Eliah R. Shamir |
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618 | (8) |
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15 Biomaterials and Artificial Organs |
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626 | (40) |
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626 | (1) |
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627 | (7) |
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634 | (9) |
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15.4 Membrane oxygenators |
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643 | (2) |
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645 | (5) |
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15.6 Biohybrid artificial organs |
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650 | (16) |
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Profiles In BME: Elias Quijano |
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659 | (7) |
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16 Biomedical Engineering and Cancer |
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666 | (39) |
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666 | (1) |
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16.2 Introduction to cancer |
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667 | (2) |
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669 | (2) |
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671 | (9) |
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680 | (6) |
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16.6 Hormonal and biological therapies |
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686 | (5) |
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16.7 Systems biology, biomedical engineering, and cancer |
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691 | (14) |
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Profiles In BME: Katie Serrano |
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699 | (6) |
Appendix A Physiological Parameters |
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705 | (10) |
Appendix B Chemical Parameters |
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715 | (6) |
Appendix C Units and Conversion Factors |
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721 | (2) |
Index |
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723 | |