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E-raamat: Bionanomaterials for Skin Regeneration

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This book gives a concise overview of bionanomaterials with applications for skin regeneration. The advantages and challenges of nanoscale materials are covered in detail, giving a basic view of the skin structure and conditions that require transdermal or topical applications. Medical applications, such as wound healing, care for burns, skin disease, and cosmetic care, such as aging of the skin and photodamage, and how they benefit from bionanomaterials, are described in detail. A final chapter is devoted to the ethical and social issues related to the use of bionanomaterials for skin regeneration. This is an ideal book for researchers in materials science, medical scientists specialized in dermatology, and cosmetic chemists working in formulations. It can also serve as a reference for nanotechnologists, dermatologists, microbiologists, engineers, and polymer chemists, as well as students studying in these fields.

1. Bionanomaterials for the skin - more than just size.- 2. Bionanomaterials for the skin - more than just size.- 3. Wound Healing and Skin Regeneration.- 4. Transdermal and Topical Delivery to the Skin.- 5. Nanoparticles, Nanomaterials and Nanocarriers.- 6. Bioavailability in Delivery to the Skin.- 7. Lipid-based Nanoparticles in Cosmetic and Pharmaceutical Products for the Skin.- 8. Bionanomaterials with Antioxidant Effect for Skin Regeneration.- 9. Nanochitosan and the Skin.- 10. Nanocellulose.- 11. Bionanomaterials from Plant Sources.- 12. Nanomaterials, Scaffolds, and Skin Tissue Regeneration.- 13. Peptide and Protein-based Nanomaterials in Applications for the Skin.- 14. Nanotoxicity and the Skin.- 15. Ethical and Social Issues Linked to Using Nanomaterials in Skin Regeneration.
1 Bionanomaterials for the Skin: More than Just Size
1(6)
References
4(3)
2 Skin, Genetic Defects, and Aging
7(10)
2.1 The Skin
7(3)
2.2 Genetic Defects in the Skin Barrier
10(2)
2.3 Skin Aging
12(5)
References
13(4)
3 Wound Healing and Skin Regeneration
17(10)
3.1 Wound Care
18(1)
3.2 Autograft Procedures
19(1)
3.3 Wound Dressings
20(1)
3.4 Delivery of Growth Factors to Wounds
21(1)
3.5 Stem Cells for Skin Regeneration
22(5)
References
23(4)
4 Transdermal and Topical Delivery to the Skin
27(10)
4.1 Chemical Enhancers
30(1)
4.2 Prodrug Approach
30(1)
4.3 Formulation Approaches
31(1)
4.4 Biochemical Enhancers
32(1)
4.5 Enhancement Using Physical Methods
32(5)
References
33(4)
5 Nanoparticles, Nanomaterials and Nanocarriers
37(10)
5.1 Nanoemulsions
40(1)
5.2 Liposomes and Related Nanostructures
40(2)
5.3 Solid Lipid Nanoparticles
42(1)
5.4 Dendrimers
43(1)
5.5 Still to Address
43(4)
References
45(2)
6 Bioavailability in Delivery to the Skin
47(6)
References
51(2)
7 Lipid-Based Nanoparticles in Cosmetic and Pharmaceutical Products for the Skin
53(8)
References
59(2)
8 Bionanomaterials with Antioxidant Effect for Skin Regeneration
61(8)
References
66(3)
9 Nanochitosan and the Skin
69(10)
9.1 Chitosan. Properties and Applications
69(2)
9.2 Nanochitosan. Preparative Methods and Characterization
71(2)
9.3 Loading Active Agents into Nanochitosan
73(6)
References
76(3)
10 Nanocellulose
79(12)
10.1 Types of Nanocelluloses. Preparation and Properties
79(3)
10.2 Nanocellulose-Based Wound Dressings
82(3)
10.3 Nanocellulose in Cosmetic Products for the Skin
85(6)
References
86(5)
11 Bionanomaterials from Plant Sources
91(12)
11.1 Phenolic Compounds from Plant Sources Delivered as Nanoparticles
91(3)
11.2 Essential Oils Delivered in Nanostructures
94(1)
11.3 Carbohydrates and Polysaccharides from Honey and Seaweed in Nanomedicines and Cosmetic Products for the Skin
95(2)
11.4 Nanoparticles Containing Hops, Aloe, Coconut Oil and Other Ingredients from Plants
97(6)
References
99(4)
12 Nanomaterials, Scaffolds, and Skin Tissue Regeneration
103(14)
12.1 Biomaterials for Scaffolds and Skin Tissue
103(4)
12.2 The Scaffolds
107(2)
12.3 Skin Substitutes
109(8)
References
114(3)
13 Peptide and Protein-Based Nanomaterials in Applications for the Skin
117(14)
13.1 Growth Factors Delivered in Nanoparticles
118(2)
13.2 Collagen, Elastin, Protease Inhibitors, Thrombin, DNA, and Stem Cells Delivered in Nanosized Carriers
120(1)
13.3 Bacteriocins Delivered in Nanostructures
121(1)
13.4 Silk Proteins in Nanostructures
122(1)
13.5 Zein-Based Nanostructures
123(2)
13.6 Melanin in Nanosize for the Skin
125(1)
13.7 siRNA Delivered to the Skin
126(5)
References
127(4)
14 Nanotoxicity and the Skin
131(4)
References
134(1)
15 Ethical and Social Issues Linked to Using Nanomaterials in Skin Regeneration
135(6)
References
139(2)
Index 141
Mihaela D. Leonida is a Professor of Chemistry at Fairleigh Dickinson University, Metropolitan Campus, in Teaneck, NJ (mleonida@fdu.edu). She received a M.S.and a Ph.D. in Chemical Engineering from Polytechnic University in Bucharest, Romania, and a second Ph.D. in Chemistry from Wesleyan University in Middletown, CT. While teaching, she has mentored research with over sixty students. Her scientific interests are broad, from wiring enzymes to bionanomaterials with antimicrobial and anti-proliferation activity, to detecting art forgeries, to materials and techniques used by artisans of times past.

 

Ish Kumar is an Associate Professor of Chemistryat Fairleigh Dickinson University,  Metropolitan Campus, in Teaneck, NJ (ikumar@fdu.edu).  He earned his B.S., M.S. and Ph.D. degrees from Panjab University, in Chandigarh, India. During his years as faculty Dr. Kumar has supervised research of more than twenty students. His research interests involve designing new molecular inhibitors using the tools of computational chemistry, enzyme structures, enzyme kinetics and chemical synthesis.
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