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E-raamat: Biosensors and Bioelectronics

(Defence Institute of Physiological and Allied Sciences (DIPAS), Defence Research and Development Organization (DRDO), Ministry of Defence, Go), , (Associate Professor of Chemistry, Biomedical Research Lab, VHNSN College, Tamilnadu, India)
  • Formaat: PDF+DRM
  • Ilmumisaeg: 02-Jul-2015
  • Kirjastus: Elsevier Science Publishing Co Inc
  • Keel: eng
  • ISBN-13: 9780128031018
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  • Formaat: PDF+DRM
  • Ilmumisaeg: 02-Jul-2015
  • Kirjastus: Elsevier Science Publishing Co Inc
  • Keel: eng
  • ISBN-13: 9780128031018

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Biosensors and Bioelectronics presents the rapidly evolving methodologies that are relevant to biosensors and bioelectronics fabrication and characterization. The book provides a comprehensive understanding of biosensor functionality, and is an interdisciplinary reference that includes a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers.Authored by a team of bioinstrumentation experts, this book serves as a blueprint for performing advanced fabrication and characterization of sensor systems—arming readers with an application-based reference that enriches the implementation of the most advanced technologies in the field. Features descriptions of functionalized nanocomposite materials and carbon fibre electrode-based biosensors for field and in vivo applicationsPresents a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymersIncludes more than 70 figures and illustrations that enhance key concepts and aid in retentionIdeal reference for those studying bioreceptors, transducers, bioinstrumentation, nanomaterials, immunosensors, nanotubes, nanoparticles, and electrostatic interactionsAuthored by a collaborative team of scientists with more than 50 years of experienced in field research and instruction combined

Muu info

An interdisciplinary reference that reflects the latest developments in biosensors and bioinstrumentation
Contributors ix
Preface xi
1 Introduction to Biosensors
1(68)
Chandran Karunakaran
Raju Rajkumar
Kalpana Bhargava
1.1 Introduction
2(1)
1.2 Basic principle of a biosensor
3(1)
1.3 Components of a biosensor
3(14)
1.4 Molecular recognition
17(6)
1.5 Classification of biosensors based on transducers
23(9)
1.6 Piezoelectric biosensors
32(3)
1.7 Magnetoelastic biosensors
35(1)
1.8 Field effect transistor-based biosensor
36(2)
1.9 Calorimetric biosensor
38(1)
1.10 Noninvasive biosensors
38(4)
1.11 Electrochemical biosensors
42(4)
1.12 Various electrochemical techniques
46(12)
1.13 Electroanalytical characteristics of biosensors
58(2)
1.14 Membranes used in biosensors for selectivity
60(1)
1.15 Biosensor electrode fabrication techniques
61(8)
References
66(3)
2 Nanocomposite Matrix Functionalization for Biosensors
69(64)
Chandran Karunakaran
Paulraj Santharaman
Mainak Das
2.1 Introduction
70(1)
2.2 Organic conducting polymers
71(15)
2.3 Inorganic nanoparticles
86(30)
2.4 Chitosan and Nafion
116(3)
2.5 Immobilization strategies
119(8)
2.6 Properties of immobilized enzymes
127(1)
2.7 The biology of enzyme immobilization
128(5)
References
128(5)
3 Enzymatic Biosensors
133(72)
Chandran Karunakaran
Thangamuthu Madasamy
Niroj Kumar Sethy
3.1 Enzymatic biosensors
135(1)
3.2 History of biosensors
135(2)
3.3 Enzymatic and nonenzymatic biosensors for various diseases
137(2)
3.4 Biomarkers for diagnosis of diseases
139(2)
3.5 Glucose oxidase-based glucose biosensors for diabetes
141(2)
3.6 Noninvasive glucose biosensor
143(1)
3.7 Implantable glucose biosensors
144(1)
3.8 Cholesterol biosensor
144(2)
3.9 Oxidative stress biomarkers
146(1)
3.10 Superoxide anion radical biosensor
147(4)
3.11 Thiol biosensor
151(2)
3.12 Nitric oxide biosensor
153(4)
3.13 Nitrite biosensor
157(1)
3.14 Nitrate reductase-based biosensor for nitrate
158(4)
3.15 Apoptosis marker
162(6)
3.16 Simultaneous determination of biomarkers
168(2)
3.17 Bienzymatic biosensor
170(1)
3.18 Enzyme inhibition-based biosensors
171(2)
3.19 Enzyme mimetic (metalloporphyrin)-based biosensors
173(8)
3.20 Screen-printed functionalized electrodes and advantages
181(1)
3.21 Nanocomposite-enhanced electrochemical biosensors
181(6)
3.22 Recent applications
187(4)
3.23 Veterinary
191(1)
3.24 Food and agriculture
192(1)
3.25 Biomedical applications
193(12)
References
196(9)
4 Immunosensors
205(42)
Chandran Karunakaran
Manickam Pandiaraj
Paulraj Santharaman
4.1 Introduction
206(1)
4.2 Antibody as biorecognition element
207(1)
4.3 Types of antibodies and antibody fragments
208(5)
4.4 Types of immunosensors
213(13)
4.5 Labeled and label-free immunosensors
226(13)
4.6 Immunosensor applications
239(3)
4.7 Future prospects
242(5)
References
243(4)
5 Instrumentation
247(72)
Krishna Arun Venkatesh
Robson Benjamin
Chandran Karunakaran
Surendran Elango
5.1 Virtual instrumentation
249(1)
5.2 Introduction to NI LabVIEW
249(1)
5.3 Difference between LabVIEW and conventional languages
250(1)
5.4 Front panel
250(2)
5.5 Block diagram
252(1)
5.6 Icon and connector panel
253(1)
5.7 Controls palette
253(1)
5.8 Function palette
254(1)
5.9 Tools palette
255(1)
5.10 Creating, editing, wiring, debugging, and saving VIs
255(3)
5.11 SubVIs -- creating subVIs
258(1)
5.12 Looping: for loop, while loop
258(2)
5.13 Shift registers and sequence locals
260(1)
5.14 Case and sequence structures
260(4)
5.15 MyDAQ
264(2)
5.16 Virtual electrochemical analyzer
266(13)
5.17 Electronics of electrochemical biosensor
279(40)
References
315(4)
Index 319
Chandran Karunakaran, PhD, is Associate Professor of Chemistry in the Biomedical Research Lab at VHNSN College, Tamilnadu, India. Dr. Karunakaran received his PhD in magnetic resonance and has worked in the National Biomedical EPR Centre and Free Radical Research Centre in Medical College of Wisconsin for the last 5 years as Postdoc, Research Scientist and Assistant Professor.