This book providesa practical approach to bronchoalveolar lavage (BAL) and its analyses, which are used worldwide in both research and clinical settings. It includes useful guidelines with a theoretic background and provides details on microscopic and flow cytometric measurements for all known differential diagnostics made with BAL analyses, from chronic diseases like COPD and ILD via infectious diseases to inherited illnesses like cystic fibrosis. It includes BAL in both adult and pediatric medicine. The text is supported throughout by illustrations and clinical cases, serving as an invaluable resource for respiratory medicine and infectious disease clinicians and trainees.
Key features:
- Uses BAL in the infectious diseases field and the search for respiratory viruses using the reverse transcription polymerase chain reaction (RT-PCR) technique.
- Presents contributions from worldwide experts.
- Clarifies the BAL technique and its diagnostic utility to respiratory physicians, cytologists, and pathologists involved in the diagnosis of pulmonary disease.
- Provides an updated perspective on the future applications of BAL techonology to research and clinical medicine.
A practical approach to bronchoalveolar lavage (BAL) and its analyses, which are used worldwide in both research and clinical settings. This book includes practical guidelines with the theoretic background and provides details on microscopic and flow cytometric measurements for all known differential diagnostics made with BAL analyses.
Part I: Performing and Analysing BAL.
1. Bronchoalveolar Lavage:
Historical Aspects.
2. Technical Aspects of Performing Bronchoalveolar
Lavage.
3. BAL as a Research Tool.
4. BAL as a Diagnostic Tool. Part 2: Using
BAL as a Diagnostic and/or Research Tool.
5. Respiratory Infections.
6.
Interstitial Lung Diseases.
7. Asthma.
8. Chronic Obstructive Lung Disease.
9. Cystic Fibrosis and Non-CF Bronchiectasis.
10. Pulmonary Malignancy.
11.
Lung Transplantation.
12. COVID-19. Part 3: Therapeutic Uses of BAL.
12.
Pulmonary Alveolar Proteinosis (PAP).
13. Donor Lung Repair.
14. Reverse
BAL. Part 4: Future Uses of BAL.
15. Perspective on Future Applications of
BAL to Basic Research and Clinical Medicine.
16. Perspective on Future
Clinical Uses of BAL.
Prof. Dr. rer. nat. Oliver Schildgen, Head of Molecular Pathology Division, Institute of Pathology, University Hospital of the Private University Witten/ Herdecke, Hospital of the City of Cologne
Priv.-Doz. Dr. rer. nat. Verena Schildgen, Private Lecturer for Molecular Pathology, Institute of Pathology, University Hospital of the Private University Witten/ Herdecke, Hospital of the City of Cologne
Prof. Dr. med. Michael Brockmann, Director and Chief Pathologist, Institute of Pathology, University Hospital of the Private University Witten/ Herdecke, Hospital of the City of Cologne
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