The International Conference on Case-Based Reasoning (ICCBR) is the preeminentinternationalmeetingoncase-basedreasoning(CBR). Through2009, ICCBR (http://www. iccbr. org) had been a biennial conference, held in alter- tion with its sister conference, the European Conference on Case-BasedReas- ing (http://www. eccbr. org), which was located in Europe. At the 2009 ICCBR,the ICCBR ProgramCommittee elected to extend ano er of consoli- tion with ECCBR. The o er was accepted by the ECCBR 2010 organizers and they have considered it approved by the ECCBR community, as the two conf- ences share a majority of Program Committee members. ICCBR and ECCBR havebeen theleading conferencesonCBR. From2010,ICCBRandECCBRwill be merged in a single conference series, called ICCBR. As there had been eight previous ICCBR events and nine previous ECCBR events, the combined series is considered the 18th ICCBR. ICCBR 2010 (http://www. iccbr. org/iccbr10) was therefore the 18th in this seriesof internationalconferenceshighlighting the mostsigni cantcontributions tothe eldofCBR. TheconferencetookplaceduringJuly19-22,2010inthecity of Alessandria,Italy, on the beautiful campus of the University of Piemonte O- entale "A. Avogadro. " Previous ICCBR conferences were held in Sesimbra, P- tugal(1995),Providence,RhodeIsland,USA(1997),SeeonMonastery,Germany (1999), Vancouver, BC, Canada (2001), Trondheim, Norway (2003), Chicago, Illinois, USA (2005), Belfast, Northern Ireland (2007), and Seattle, Washington, USA (2009). Day 1 of the conference hosted an Applications Track, the second Doctoral Consortium, and the third Computer Cooking Contest. The Applications Track featured ?elded applications and CBR systems demos in industrial and scienti c settingswithanemphasis ondiscussionandnetworkingbetweenresearchersand industrials.