| Contributors |
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ix | |
| Preface |
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xi | |
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1 Hedgehog on track: Long-distant signal transport and transfer through direct cell-to-cell contact |
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1 | (24) |
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2 | (2) |
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2 Dynamic cytonemes and gradient formation models |
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4 | (3) |
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3 Cytoneme-mediated Hh signaling between different cell types |
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7 | (2) |
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4 Cytoneme establishment and regulation: The weight of cell adhesion in Hh signaling |
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9 | (3) |
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5 Transport through the extending protrusion |
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12 | (4) |
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6 Signal transfer, reception and retraction |
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16 | (2) |
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18 | (7) |
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19 | (1) |
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19 | (6) |
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2 Receptor control by membrane-tethered ubiquitin ligases in development and tissue homeostasis |
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25 | (66) |
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28 | (2) |
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2 Classification of membrane-tethered E3s |
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30 | (6) |
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3 The R-spondin-ZNRF3/RNF43 signaling system tunes WNT and BMP receptor abundance |
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36 | (29) |
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4 Regulation of Hedgehog and melanocortin receptor abundance by the membrane-recruited E3 MGRN1 |
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65 | (10) |
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75 | (2) |
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77 | (14) |
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77 | (1) |
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78 | (13) |
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3 An itch for things remote: The journey of Wnts |
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91 | (38) |
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1 Introduction to Wnt signaling |
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92 | (2) |
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2 Biogenesis and transport to the plasma membrane |
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94 | (4) |
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98 | (13) |
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4 Wnt receptors and their regulation |
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111 | (1) |
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112 | (2) |
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114 | (1) |
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115 | (14) |
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116 | (1) |
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116 | (13) |
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4 Dynamic regulation of human epidermal differentiation by adhesive and mechanical forces |
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129 | (20) |
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130 | (1) |
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2 Epidermal adhesion mechanisms |
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131 | (2) |
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3 Keratinocyte-substrate interactions at the single cell level |
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133 | (2) |
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4 Role of cell-cell adhesion in regulating differentiation: A reductionist approach |
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135 | (1) |
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5 Cross-talk between cell-cell and cell-ECM adhesion mechanisms: Building a multilayered epidermis |
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136 | (2) |
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6 Physical forces and the control of differentiation of individual keratinocytes |
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138 | (2) |
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7 Physical forces acting at the level of epidermal assembly |
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140 | (2) |
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8 Conclusions and future directions |
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142 | (7) |
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143 | (1) |
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144 | (5) |
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5 Cell signaling pathways controlling an axis organizing center in the zebrafish |
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149 | (62) |
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150 | (2) |
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2 Defining the zebrafish dorsal organizer |
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152 | (3) |
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3 Establishment of the zebrafish dorsal organizer |
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155 | (19) |
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4 Cell signaling underlying the organizer's dorsalizing activities |
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174 | (21) |
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195 | (16) |
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195 | (1) |
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195 | (16) |
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6 Local BMP signaling: A sensor for synaptic activity that balances synapse growth and function |
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211 | (44) |
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212 | (3) |
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2 Synapse assembly and recruitment of neurotransmitter receptors at the fly neuromuscular junction |
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215 | (6) |
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3 Distinct mechanisms recruit type-A and type-B glutamate receptors |
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221 | (5) |
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4 Pmad as a sensor of synapse activity |
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226 | (5) |
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5 A positive feedback loop stabilizes glutamate receptor subtypes as a function of activity |
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231 | (7) |
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6 Motor neurons coordinate multiple BMP signaling to balance NMJ growth with synapse maturation/stabilization |
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238 | (5) |
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243 | (12) |
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245 | (1) |
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245 | (10) |
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7 Wnt-frizzled planar cell polarity signaling in the regulation of cell motility |
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255 | (44) |
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1 Overview of planar cell polarity (PCP) signaling |
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256 | (6) |
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2 PCP and cell motility in Drosophila |
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262 | (8) |
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3 PCP regulated cell motility processes in vertebrates |
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270 | (17) |
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287 | (12) |
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288 | (1) |
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289 | (10) |
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8 Talking to your neighbors across scales: Long-distance Notch signaling during patterning |
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299 | |
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300 | (2) |
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2 Patterning in space and time |
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302 | (4) |
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3 Notch mediated patterning across scales |
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306 | (11) |
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4 Modeling long-range Notch signaling |
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317 | (3) |
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5 Case studies of long-range Notch signaling |
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320 | (3) |
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6 Evolvability of patterns |
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323 | (2) |
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325 | |
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326 | (1) |
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326 | |
Lisainfo e-raamatute kohta