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E-raamat: Certifying Central Facility Beamlines for Biological and Chemical Crystallography and Allied Methods

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This book briefs beamline providers and users on what to look for when selecting experiments for a given type of facility and beamline so that beamtime usage and effectiveness can be maximized. It navigates facility publications, as well as data management and sharing policies. Like this, the information presented helps avoid potential pitfalls between facility and user on these important post-experiment aspects. Allied analytical methods are also described in terms of their certification for confident provision and use.

1.A beginners guide to synchrotron radiation and X-ray lasers.- 2.A
beginners guide to neutron reactor and spallation sources and detectors.-
3.A beginners guide to detectors in use at X-ray beamlines and their
calibration.- 4.Introduction to X-ray beamlines for crystallography.-
5.Guidance in preparing the experiment at your home facility including sample
preparation.- 6.Beamline scientist perspective.- 7.Beamline user
perspective.- 8.Fixed wavelength high intensity beamline.- 9.Tuneable
wavelength beamline.- 10.Laue diffraction beamline.- 11.Microfocus beamline.-
12.Serial crystallography beamline: synchrotron.- 13.Serial crystallography
beamline: X-ray laser.- 14.Time-resolved crystallography.- 15.Electron
crystallography facility.- 16.Neutron crystallography instruments.-
17.Facility data archiving policy considerations.- 18.Facility publication
authorship policies.- 19.Sample environment, cryostats and or containment,
light sources for photo-initiation or mixing devices for reactions in a
crystal.- 20.Electron biological imaging centres at the SR facilities:
Diamond, ESRF, Soleil and SSRL/SLAC as examples.- 21.NMR crystallography.-
22.Small and Wide-Angle Scattering beamlines.- 23.X-ray absorption
spectroscopy beamlines.- 24.Mass spectroscopy.- 25.UV/Vis and Infra-red
spectroscopy.- 26.Data analysis and software.- 27.Safety Matters.-
28.Theoretical and Computational Sciences.- 29.Summary.- 30.So, to the
Measuring Team briefing before the Experiment.
John R Helliwell, DSc (Physics, University of York), DPhil (Molecular Biophysics, Oxford University) is Emeritus Professor of Chemistry at The University of Manchester. At the Synchrotron Radiation Source at the UKs Daresbury Laboratory he held various appointments between 1979 to 2008, including as Director of Synchrotron Radiation Science. He is a Fellow of the Institute of Physics, the Royal Society of Chemistry, the Royal Society of Biology, the American Crystallographic Association, an Honorary Member of the British Crystallographic Association and of the British Biophysical Society, a Corresponding member of the Royal Academy of Sciences & Arts of Barcelona, Spain and an Honorary Member of the National Institute of Chemistry, Slovenia. His awards include the European Crystallographic Association Eighth Max Perutz Prize 2015, the American Crystallographic Association Patterson Award 2014, and the Professor K Banerjee Endowment Lecture Silver Medal of the Indian Association for the Cultivation of Science 2001. He has served as President of the European Crystallographic Association (2007 to 2010), Chairman of the International Union of Crystallographys (IUCr) Commission on Journals (1996-2005), Chairman of the IUCr Diffraction Data Deposition Working Group (2011 to 2017) and its Committee on Data (2017 onwards) and its Representative to CODATA (2012 onwards).