Covering the role of circadian rhythms in pharmacokinetics and pharmacodynamics, this book provides practical tools for clinicians and researchers to optimize treatments in cardiovascular disease, oncology, and sleep disorders. A comprehensive guide on the science of timed drug administration to maximize therapeutic benefits.
Chronopharmacology: Time-Dependent Pharmacotherapy explores the cutting-edge science of tailoring drug administration to the body's natural biological rhythms, known as circadian rhythms. This comprehensive book provides healthcare professionals and researchers a deep understanding of how the timing of drug administration can impact therapeutic efficacy, safety, and patient outcomes. By integrating knowledge from pharmacology, chronobiology, and clinical medicine, the book offers both theoretical insights and practical guidelines for applying chronopharmacology in the treatment of diseases like cardiovascular disorders, cancer, and sleep-related conditions. Through case studies and the latest research on circadian-based drug delivery systems, this text is an invaluable resource for clinicians aiming to optimize patient care and researchers exploring new frontiers in personalized medicine.
Preface.
1. The Circadian System and Biological Rhythms.
2. Historical
Perspectives and Evolution of Chronotherapy.
3. Fundamental Concepts of
Chronopharmacokinetics and Chronopharmacodynamics.
4. Chronotherapy in
Cardiovascular Disease.
5. Time-dependent Drug Responses in Oncology.
6.
Managing Sleep Disorders Through Chronopharmacology.
7. Chronopharmacological
Approaches to Diabetes and Metabolic Disorders.
8. Chrono-drug Delivery
Systems: Timed-release Formulations.
9. The Role of Artificial Intelligence
in Optimizing Drug Timing.
10. Future Trends and Clinical Applications of
Chronopharmacology. Index.
Mohd Aftab Siddiqui is an Associate Professor at Integral University's Faculty of Pharmacy, Lucknow, India. He obtained a PhD in Pharmacology in 2020, following distinguished M Pharm (2015) and B Pharm (2013) degrees. He has an excellent academic record and has significant teaching and research experience. His work focuses on natural products, drug discovery, and pharmacological interventions. Dr. Siddiqui has authored articles, contributed to book chapters, edited books, and served in administrative roles and professional societies. Honored with awards like the "Young Scientist Award," his ongoing research and publications advance pharmacological sciences.
Afreen Usmani is an Associate Professor and Vice Principal at MESCO Institute of Pharmacy, Amroha, India. She specializes in nanomedicine and targeted drug delivery. A PhD graduate in Pharmacology from Integral University, India, she has authored over 32 research articles, numerous book chapters, and more than 12 academic books widely recognized in pharmaceutical education. Holding multiple patents, she contributes to pharmacology, toxicology, nanotechnology, and drug development. Dr. Usmani actively participates in conferences, serves on journal editorial boards, and is a lifetime member of the Society for Progressive Letters, continuing to inspire and advance pharmaceutical sciences.
Mohd Nazam Ansari is a Professor in Pharmacology and Toxicology at PSAU, Saudi Arabia. He obtained a PhD in Pharmacology in 2008 from Hamdard University, India. With over 150 publications, 13 research projects, and extensive global conference participation, he is a recognized expert in his field. Dr. Ansari is a member of prominent pharmacological societies and serves on editorial boards of reputed journals.
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