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E-raamat: Clinical Oncology: Basic Principles and Practice

(Cancer Centre, Mount Vernon Hospital, UK)
  • Formaat: 397 pages
  • Ilmumisaeg: 30-Apr-2020
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781351972000
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  • Formaat: 397 pages
  • Ilmumisaeg: 30-Apr-2020
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781351972000
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This popular textbook provides a clear and comprehensive introduction to the principles and practice of clinical oncology. Ideal for medical undergraduates, clinicians and other health professionals who want to increase their understanding of the challenges of managing patients with cancer, the book enables readers to learn and then test themselves on all aspects of cancer medicine, from epidemiology, aetiology, pathogenesis and presentation, through to diagnosis, staging, management and prognosis.

List of abbreviations
ix
Preface xiii
Acknowledgement xv
1 Pathogenesis of cancer
1(8)
Genetic factors
1(1)
Chemical factors
2(2)
Physical factors
4(1)
Viral factors
5(1)
Immune factors
6(1)
Endocrine factors
7(2)
2 Principles of cancer diagnosis and staging
9(12)
Securing a tissue diagnosis
9(1)
Principles of cancer staging
10(6)
The TNM staging system
16(5)
3 Decision-making and communication
21(14)
Treatment options
21(3)
Quality of life
24(1)
Communication
24(3)
Clinical evidence and clinical trials
27(8)
4 Principles of surgical oncology
35(4)
Management of the primary tumour
35(1)
Combined surgery and radiotherapy
35(1)
Management of regional lymph nodes
36(1)
Palliative surgery
37(2)
5 Principles of radiotherapy
39(12)
Types of radiation
39(1)
Biological actions of ionizing radiation
39(1)
Radiotherapy equipment
40(2)
Clinical use of radiotherapy
42(4)
Side effects of radiotherapy
46(1)
Radiation protection
47(4)
6 Principles of systemic treatment
51(16)
Chemotherapy agents
51(4)
Drug resistance
55(1)
Administration of chemotherapy
56(4)
Hormone therapy
60(2)
Biological therapy
62(1)
Immunotherapy
62(1)
Growth factors
63(1)
Experimental chemotherapy
63(4)
7 Lung cancer and mesothelioma
67(22)
Lung cancer
67(16)
Mesothelioma
83(6)
8 Breast cancer
89(26)
Epidemiology
89(1)
Aetiology
89(1)
Pathology
90(2)
Natural history
92(1)
Symptoms
93(2)
Signs
95(1)
Differential diagnosis
96(1)
Investigations
96(2)
Staging
98(1)
Treatment
98(12)
Prognosis
110(2)
Screening
112(1)
Prevention
113(2)
9 Gastrointestinal cancer
115(38)
Carcinoma of the oesophagus
115(6)
Carcinoma of the stomach
121(5)
Carcinoma of the pancreas
126(5)
Hepatocellular cancer
131(4)
Cholangiocarcinoma
135(3)
Carcinoma of the gallbladder
138(1)
Carcinoma of the colon and rectum
138(8)
Carcinoma of the anus
146(3)
Tumours of the peritoneum
149(4)
10 Urological cancer
153(26)
Renal cell carcinoma
153(3)
Prostate cancer
156(9)
Bladder cancer
165(5)
Cancer of the testis
170(4)
Cancer of the penis
174(5)
11 Gynaecological cancer
179(22)
Cervical cancer
179(6)
Endometrial cancer
185(3)
Ovarian cancer
188(4)
Cancer of the vagina
192(2)
Cancer of the vulva
194(2)
Choriocarcinoma
196(5)
12 CNS tumours
201(16)
Astrocytoma
204(2)
Oligodendroglioma
206(1)
Meningioma
206(1)
Pituitary tumours
207(1)
Craniopharyngioma
208(1)
Pineal tumours
209(1)
Germ cell tumours
209(1)
Ependymomas
210(1)
Medulloblastoma
210(1)
Chordoma
211(1)
Haemangioblastoma
211(1)
Lymphoma
211(1)
Metastases
211(2)
Carcinomatous meningitis
213(4)
13 Head and neck cancer
217(14)
Carcinoma of the oral cavity
217(6)
Carcinoma of the oropharynx
223(1)
Carcinoma of the larynx
223(1)
Carcinoma of the hypopharynx
224(1)
Carcinoma of the nasopharynx
225(1)
Carcinoma of the paranasal sinuses
226(1)
Salivary gland tumours
226(2)
Orbital tumours
228(3)
14 Endocrine tumours
231(14)
Thyroid cancer
231(7)
Tumours of the parathyroid gland
238(1)
Tumours of the adrenal glands
238(2)
Carcinoid tumours
240(3)
Multiple endocrine neoplasia (MEN)
243(2)
15 Sarcomas
245(14)
Soft-tissue sarcomas
245(5)
Osteosarcoma
250(4)
Ewing sarcoma
254(2)
Other bone tumours
256(3)
16 Lymphoma
259(20)
Hodgkin lymphoma
259(7)
Non-Hodgkin lymphoma (NHL)
266(13)
17 Haematological malignancy
279(22)
Leukaemia
279(11)
Multiple myeloma
290(11)
18 Paediatric cancer
301(16)
Leukaemia
301(1)
Central nervous system tumours
301(3)
Bone and soft-tissue tumours
304(2)
Lymphoma
306(1)
Neuroblastoma
307(3)
Nephroblastoma (Wilms' tumour)
310(2)
Other tumours
312(5)
19 Skin cancer
317(14)
Squamous and basal cell carcinoma
317(6)
Melanoma
323(5)
Metastases
328(1)
Rare tumours
328(3)
20 Carcinoma of unknown primary
331(6)
21 Oncological emergencies
337(12)
Hypercalcaemia
337(1)
Spinal cord and cauda equina compression
338(2)
Superior vena cava obstruction
340(2)
Neutropenic sepsis
342(1)
Tumour lysis syndrome
343(1)
Toxicities related to immunotherapy agents
343(6)
22 Palliative care
349(12)
Pain control
349(6)
Other symptoms
355(2)
The dying patient
357(4)
Appendix 1 Worldwide cancer burden - males and females 361(2)
Appendix 2 Worldwide cancer burden - males 363(2)
Appendix 3 Worldwide cancer burden - females 365(2)
Appendix 4 Answers to self-assessment questions 367(2)
Index 369
Peter Hoskin is Consultant in Clinical Oncology at Mount Vernon Hospital, Northwood, London and Professor in Clinical Oncology at University College London, UKRobert Glynn Jones is Consultant in Clinical Oncology at Mount Vernon Hospital, Northwood, London, UKPeter Ostler is Consultant in Clinical Oncology and Divisional Lead at Mount Vernon Hospital, Northwood, London, UK