Life's context is uncertain environmental information, communication is its means, and genes are its tools. Evolution is its yield as continuous non-random self-referential cellular problem-solving.
Cognition-Based Evolution is the first comprehensive alternative to 20th-century Neodarwinism, proposing a radical 21st-century evolutionary framework with a novel point of origination: all cells are intelligent and must measure uncertain environmental information to sustain themselves. In Cognition-Based Evolution, life is defined by cognition. From this differential stance, evolutionary biology transforms into the science of why, how, what, and with whom cells measure and communicate under stressful environmental conditions. Life's context is uncertain environmental information, communication is its means, and genes are its tools. Evolution is its yield as continuous non-random self-referential cellular problem-solving.
Introduction: Evolution Recast. Neodarwinism: Evolution in the 20th
Century. 21st Century Evolution: The Intelligent Measuring Cell. The Cellular
Information Cycle and Biological Information Management. The Senome: The
Cellular Connection with Environmental Information. The N-space Episenome:
Concordant Cellular Information. Natural Cellular Engineering as
Multicellular Problem-solving. Non-random Variations in Natural Cellular
Engineering. The Virome and Natural Viral-Cellular Engineering. Holobionts: A
Consensual We. The Role of the Microbiome in the Evolution and Development
of Holobionts. Four Domains and the Primacy of the Unicellular State.
Speciation. Sexual Reproduction and its Impact on Evolutionary Variation.
Extinction . Old Controversies RevisitedWhere is the Cusp of Creativity? The
Primacy of Cellular Consciousness. How Might Biology Instruct Physics? A
Separation from the Past. ConclusionThe Intelligent Measuring Cell.
Appendix: Differential Features Between Cognition-Based Evolution and the
Neodarwinian Modern Synthesis.
Dr. William B. Miller, Jr. is a graduate of the Six-Year Medical Honors Program at Northwestern University and is a member of the prestigious Alpha Omega Alpha medical honors society. Thirty years of medical observations led to a conviction that the dominant assessment of disease causation and evolutionary development is insufficient, demanding a revitalized evolutionary narrative. Dr. Miller is an internationally recognized and widely cited evolutionary biologist and author and co-author of seven books on evolutionary mechanisms.
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