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E-raamat: Computational Biology of Non-Coding RNA: Methods and Protocols

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  • Formaat: EPUB+DRM
  • Sari: Methods in Molecular Biology 2883
  • Ilmumisaeg: 19-Dec-2024
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071642900
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Computational Biology of Non-Coding RNA: Methods and ProtocolsSuurem pilt
  • Formaat: EPUB+DRM
  • Sari: Methods in Molecular Biology 2883
  • Ilmumisaeg: 19-Dec-2024
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071642900
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This second edition details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.





 





Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
Overview of the different classes of small RNAs during B cell
development.- A Current Perspective of Medical Informatics Developments for a
Clinical Translation of (non-coding)RNAs and Single-Cell Technologies.-
Non-coding RNA networks in infection.- The role of non-coding RNAs in
tumorigenesis, diagnosis/prognosis, and therapeutic strategies for cutaneous
melanoma.- A review on circular RNA translation and its implications in
disease.- Modeling ncRNA-Mediated Circuits in Cell Fate Decision: From
Systems Biology to Synthetic Biology.- Mathematical modeling for oscillations
driven by noncoding RNAs.- Out-of-equilibrium ceRNA crosstalk.- Mechanistic
Modelling the Role of MicroRNAs and Transcription Factors in Disease
Progression.- Architects and Partners: The Dual Roles of Non-Coding RNAs in
Gene Fusion Events.- Unveiling Long Non-Coding RNA Networks from Single-Cell
Omics Data through Artificial Intelligence.- LncRNA recognition associated
CpG island detection and methylation analysis.- Computational resources for
lncRNA functions and targetome.- Temporal expression analysis to unravel gene
regulatory dynamics by microRNAs.- Computational prediction of gene
regulation by lncRNAs.- Structure-based prediction of lncRNA-protein
interactions by deep learning.- Modelling ncRNA Synergistic Regulation in
Cancer.- A Practical Guideline for MicroRNA Sequencing Data Analysis in
Chronic Lymphocytic Leukemia.- A Network Biology-Guided Investigation of the
Long Non-Coding RNAs role in Glaucoma.- ncRNA editing: Functional
Characterization and Computational Resources.
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