New edition of a reference in which medical experts provide updated information relating to connective tissue and its heritable disorders. The first 19 chapters (biology of extracellular matrix) address the morphological, physiological, and molecular biological aspects of the connective tissues and their constituents under normal conditions. Subsequent contributions (heritable disorders of connective tissue) discuss specific disorders, or groups of disorders, including a number of new additions related to the less common or only recently defined conditions. A new appendix includes information on collagen metabolites in body fluids. Edited by Peter M. Royce and Beat Steinmann of the U. of Zurich Children's Hospital. Annotation c. Book News, Inc., Portland, OR (booknews.com)
The Second Edition of Connective Tissue and Its Heritable Disorders: Molecular, Genetic, and Medical Aspects is the definitive reference text in its field, with over 40% more pages on the nature, diagnosis, and treatment of disease than its predecessor. Collecting new research on disorders detailed in the first edition as well as on those previously excluded, editors Peter Royce and Beat Steinmann provide the most up-to-date clinical and scientific information for medical specialists treating affected individuals. Features of this revised and updated volume include detailed reviews of the clinical diagnosis, mode of inheritance, risk of recurrence, and prenatal diagnosis of each inherited connective tissue disorder; a thorough description of the morphology of connective tissues; a completely updated and revised section on the biology of the extracellular matrix; and the addition of syndromes such as craniosyntosis, and disorders of sulfate metabolism.
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