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E-raamat: Current Developments in Biotechnology and Bioengineering: Technologies for Production of Nutraceuticals and Functional Food Products

Edited by , Edited by (Scientist, Institute of Bioresources and Sustainable Development, Sikkim Centre, Sikkim, Gangtok, India), Edited by (Executive Director, Centre for Energy and Environmental Sustai), Edited by , Edited by (Center of Innovative and Applied Bioprocessing, Mohali, India)
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  • Ilmumisaeg: 30-Nov-2021
  • Kirjastus: Elsevier Science Publishing Co Inc
  • Keel: eng
  • ISBN-13: 9780128236437
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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 30-Nov-2021
  • Kirjastus: Elsevier Science Publishing Co Inc
  • Keel: eng
  • ISBN-13: 9780128236437
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Current Developments in Biotechnology and Bioengineering: Technologies for Production of Nutraceuticals and Functional Food Products covers a wide range of topics surrounding microbial processes and their use in the production of high value and fermented functional foods. The bioactive compounds covered in the book include those derived from food substrates in bioactive peptides, transformed polyphenols, oligosaccharides, prebiotics and functional lipids. The scientific information related to recombinant microorganisms and their role in the production of nutraceutical and functional foods is also discussed, with the translational aspects of microbial bioprocess technologies fully illustrated.

In addition, current requirements and future perspectives of industrial and food biotechnology are extensively covered.

  • Provides a deep and conceptual understanding of enzyme catalysis, enzyme engineering, discovery of novel enzymes, and technology perspectives
  • Offers information about inventions and advancements in microbial process development for the production of high value nutraceuticals and fermented functional foods
  • Includes updated references for further understanding of fermentation technology in the functional foods industry
List of contributors
xiii
About the editors xix
Preface xxiii
1 Microbial bioprocesses for production of nutraceuticals and functional foods
1(30)
Loreni Chiring Phukon
Sudhir P. Singh
Ashok Pandey
Amit Kumar Rai
1.1 Introduction
1(1)
1.2 Microbial production of nutraceuticals and functional foods
2(14)
1.3 Conclusions and perspectives
16(15)
References
16(15)
2 Microbial transformation for improving food functionality
31(16)
Antonia Terpou
Amit Kumar Rai
2.1 Microbes and food production over the centuries
31(2)
2.2 Bioactive compounds as functional food ingredients
33(1)
2.3 Health-promoting bioactive compounds synthesized via microbial transformation
34(4)
2.4 Trends in the delivery of bioactive compounds targeting enhanced food functionality
38(2)
2.5 Fermented food as potential for antiviral therapy
40(1)
2.6 Conclusions and perspectives
41(6)
References
41(6)
3 Bioactive peptide production in fermented foods
47(26)
Anja Dullius
Gabriela Rabaioli Rama
Maiara Giroldi
Marcia Ines Goettert
Daniel Neutzung Lehn
Claucia Fernanda Volken De Souza
3.1 Introduction
47(1)
3.2 Bioactive peptides in fermented dairy products
48(4)
3.3 Bioactive peptides in fermented meat products
52(3)
3.4 Bioactive peptides in fermented vegetables
55(2)
3.5 Biotechnological progress for industrial production of bioactive peptides
57(5)
3.6 Conclusions and perspectives
62(11)
References
63(10)
4 Probiotics in fermented products and supplements
73(36)
Neha Baliyan
Madhu Kumari
Poonam Kumari
Kiran Dindhoria
Srijana Mukhia
Sanjeet Kumar
Mahesh Gupta
Rakshak Kumar
4.1 Introduction
73(1)
4.2 Probiotic bacteria
74(6)
4.3 Probiotics in fermented foods
80(6)
4.4 Interactions between probiotics and components of fermented foods
86(1)
4.5 Impact of probiotics on the human gut microbiome
87(3)
4.6 Ethnic fermented probiotics products translated to industry and their advantages over nonfermented products
90(2)
4.7 Challenges in the probiotics industry and future prospects
92(3)
4.8 Conclusions and perspectives
95(14)
Acknowledgments
95(1)
References
96(13)
5 Fructooligosaccharides production and the health benefits of prebiotics
109(30)
Clarisse Nobre
Livia S. Simoes
Daniela A. Goncalves
Paulo Berni
Jose A. Teixeira
5.1 Introduction
109(1)
5.2 Fructans occurrence, chemical structure, technological properties, and market
110(2)
5.3 Fructooligosaccharides production
112(8)
5.4 Role of prebiotics in control of human diseases
120(7)
5.5 Conclusions and perspectives
127(12)
Acknowledgments
128(1)
References
128(11)
6 Production of food enzymes
139(18)
Qinghua Li
Guoqiang Zhang
Guocheng Du
6.1 Introduction
139(2)
6.2 Applications of food enzymes in food industry
141(3)
6.3 Current progress and challenges in food enzymes production
144(3)
6.4 Advanced technologies for food enzymes production
147(4)
6.5 Conclusions and perspectives
151(6)
References
151(6)
7 Production of fibrinolytic enzymes during food production
157(32)
Ali Muhammed Moula Ali
Sri Charan Bindu Bavisetty
Maria Gullo
Sittiwat Lertsiri
John Morris
Salvatore Massa
7.1 Introduction
157(1)
7.2 Mechanism of blood clotting and fibrinogenesis
158(1)
7.3 Mechanism of action of FEs: fibrinolysis and thrombolysis
159(1)
7.4 Classification of FEs
160(1)
7.5 Purification of FEs
160(1)
7.6 Biochemical characterization of FEs
161(2)
7.7 Sources of FEs
163(7)
7.8 Production of FEs
170(4)
7.9 Applications
174(3)
7.10 Conclusions and perspectives
177(12)
References
177(12)
8 Microbial production and transformation of polyphenols
189(20)
Puja Sarkar
Md Minhajul Abedin
Sudhir P. Singh
Ashok Pandey
Amit Kumar Rai
8.1 Introduction
189(1)
8.2 Types of polyphenols and their health benefits
190(2)
8.3 Microbial production and enhancement of polyphenols during fermentation
192(8)
8.4 Effect of gut microbes on polyphenols
200(1)
8.5 Conclusions and perspectives
200(9)
References
201(8)
9 Bioprocess technologies for production of structured lipids as nutraceuticals
209(30)
Suzana Ferreira-Dias
Natalia Osorio
Carla Tecelao
9.1 Introduction
209(1)
9.2 General aspects of lipids: definition, structure, and properties
210(3)
9.3 The role of lipids in human nutrition
213(2)
9.4 Production of structured lipids
215(15)
9.5 Conclusions and perspectives
230(9)
List of symbols
230(9)
References
231(8)
10 Microbial fermentation for reduction of antinutritional factors
239(22)
Ebenezer Jeyakumar
Rubina Lawrence
10.1 Introduction
239(1)
10.2 Nutritive and antinutritive properties in food
240(8)
10.3 Neutralizing antinutritional factors in fermented foods
248(6)
10.4 Conclusions and perspectives
254(7)
References
255(6)
11 Mycotoxins in foods: impact on health
261(12)
Samuel Ayofemi Olalekan Adeyeye
11.1 Introduction
261(1)
11.2 Mycotoxins in foods
262(2)
11.3 Mycotoxins in foods: impact on health
264(2)
11.4 Economic implications of mycotoxins in foods
266(1)
11.5 Mitigation and control of mycotoxins in foods
266(2)
11.6 Conclusions and perspectives
268(5)
References
269(4)
12 Gut microbes: Role in production of nutraceuticals
273(28)
Palanisamy Athiyaman Balakumaran
K. Divakar
Raveendran Sindhu
Ashok Pandey
Parameswaran Binod
12.1 Introduction
273(1)
12.2 Role of the gut microbiome in human health
274(2)
12.3 Nutraceuticals and gut microbes
276(1)
12.4 Nutrigenomics: Gut microbes and health benefits
276(2)
12.5 Developments in nutraceuticals production using gut microbes
278(1)
12.6 Microbial strategies for the production of nutraceuticals
279(1)
12.7 Production of gamma-aminobutyric acid and hyaluronic acid by lactic acid bacteria
279(1)
12.8 Vitamin B12 and folate production by Propionibacteria
280(1)
12.9 Nutraceuticals production by Bacillus subtilis
281(1)
12.10 Glutathione, carotenoids, and other nutraceuticals production by yeasts
281(1)
12.11 Metabolic engineering of microbes for the production of nutraceuticals
282(5)
12.12 Market trends in the production of nutraceuticals
287(1)
12.13 Conclusions and perspectives
288(13)
Acknowledgment
289(1)
References
289(12)
13 Bioprocessing of agri-food processing residues into nutraceuticals and bioproducts
301(22)
Vinod Kumar
Sudesh K. Yadav
Anil K. Patel
Bhuwan B. Mishra
Vivek Ahluwalia
Lalitesh K. Thakur
Jitendra Kumar
13.1 Introduction
301(2)
13.2 Agri-food processing residues and valorization
303(11)
13.3 Conclusions and perspectives
314(9)
Acknowledgments
314(1)
References
314(9)
14 Genetically modified microorganisms for enhancing nutritional properties of food
323(14)
Pardeep Kumar Bhardwaj
Kashmir Singh
14.1 Introduction
323(1)
14.2 Techniques used for genetic modification
324(1)
14.3 Advantages of genetic modification
324(1)
14.4 Need for genetically modified food products
324(1)
14.5 Microorganisms as source of food enzymes
325(1)
14.6 Use of genetically modified microbes in food industry
325(2)
14.7 Characteristics of genetically modified microorganisms
327(3)
14.8 Products development using genetically modified microorganisms in food industry
330(2)
14.9 Fermented food products and their health benefits
332(1)
14.10 Conclusions and perspectives
333(4)
References
334(3)
15 Exopolysaccharide producing microorganisms for functional food industry
337(18)
Rwivoo Baruah
Kumari Rajshee
Prakash M. Halami
15.1 Introduction
337(1)
15.2 Exopolysaccharides
338(1)
15.3 Important exopolysaccharides producing bacterial genera
339(6)
15.4 Fermented food containing exopolysaccharides
345(2)
15.5 Technological advantages of exopolysaccharides
347(1)
15.6 Health benefits of exopolysaccharides
347(2)
15.7 Conclusions and perspectives
349(6)
Acknowledgments
349(1)
References
349(5)
Further Reading
354(1)
16 Microbial metabolites beneficial in regulation of obesity
355(22)
Khushboo
Kashyap Kumar Dubey
16.1 Introduction
355(1)
16.2 Composition of gut microbiota
356(1)
16.3 Obesity and lipid metabolism
357(1)
16.4 Pancreatic lipase
358(1)
16.5 Antilipid effect of Cineromycin B
359(1)
16.6 Gut---brain axis
359(1)
16.7 Short-chain fatty acids
360(2)
16.8 New players for obesity treatment
362(2)
16.9 Orlistat: Food and Drug Administration-approved antiobesity drug
364(1)
16.10 Bacillus natto probiotics
365(1)
16.11 Inhibitory effect of fermented skim milk
366(1)
16.12 Conclusions and perspectives
367(10)
References
367(10)
17 Potential bovine colostrum for human and animal therapy
377(20)
Maria Giovana Binder Pagnoncelli
Fernanda Guilherme Do Prado
Juliane Mayara Casarim Machado
Andreia Anschau
Carlos Ricardo Soccol
17.1 Introduction
377(1)
17.2 Bovine colostrum composition
378(4)
17.3 Passive immunity mechanism in human and different animal species
382(1)
17.4 Bovine colostrum application for human therapy
383(3)
17.5 Bovine colostrum application for animal therapy
386(3)
17.6 Conclusions and perspectives
389(8)
References
389(8)
18 Colostrum new insights: products and processes
397(26)
Alessandra Cristine Novak Sydney
Isadora Kaniakikeda
Maria Carolina De Oliveira Ribeiro
Eduardo Bittencourt Sydney
Dao Pedro De Carvalho Neto
Susan Grace Karp
Cristine Rodrigues
Carlos Ricardo Soccol
18.1 Introduction
397(1)
18.2 New insights in colostrum production process and quality control
398(4)
18.3 Colostrum patents
402(12)
18.4 Commercial bovine colostrum products
414(3)
18.5 Conclusion and perspectives
417(6)
References
418(5)
Index 423
Dr. Amit Kumar Rai is presently working as Scientist C at Institute of Bioresources and Sustainable Development, Regional Centre, Sikkim. He has completed his doctorate from CSIR-Central Food Technological Research Institute, Mysore on application of lactic acid fermentation for recovery nutraceuticals from fish and animal processing by-products. As an independent researcher, Dr. Amit has contributed in the area of Food Biotechnology for the production of nutraceuticals and functional foods rich in bioactive peptides and isoflavones using microorganisms associated with traditional fermented foods of North East India. To his credit, he has totally 45 publications including 31 publications in SCI Journals and 12 chapters in the book published by various International publishers. His performance as a researcher has resulted in the bestowment of the Young Scientist Award 2016 from Association of Food Scientist and Technologists (India), Young Scientist Award 2015 by Association of Microbiologist of India, AU-CBT Excellence Award 2009 by the Biotech Research Society of India, Award for excellence in Food Biotechnology 2016 from Society of Applied Biotechnology and several best presentation award at National and International conferences. Dr. Amit Kumar Rai is presently working as Scientist C at Institute of Bioresources and Sustainable Development, Regional Centre, Sikkim. He has completed his doctorate from CSIR-Central Food Technological Research Institute, Mysore on application of lactic acid fermentation for recovery nutraceuticals from fish and animal processing by-products. As an independent researcher, Dr. Amit has contributed in the area of Food Biotechnology for the production of nutraceuticals and functional foods rich in bioactive peptides and isoflavones using microorganisms associated with traditional fermented foods of North East India. To his credit, he has totally 45 publications including 31 publications in SCI Journals and 12 chapters in the book published by various International publishers. His performance as a researcher has resulted in the bestowment of the Young Scientist Award 2016 from Association of Food Scientist and Technologists (India), Young Scientist Award 2015 by Association of Microbiologist of India, AU-CBT Excellence Award 2009 by the Biotech Research Society of India, Award for excellence in Food Biotechnology 2016 from Society of Applied Biotechnology and several best presentation award at National and International conferences. Dr. Sudhir P. Singh obtained his Ph.D. in the year 2011 from University of Lucknow, India. Subsequently, he worked as research associate and then as Project Scientist at National Agri-Food Biotechnology Institute, Mohali, India. He joined Center of Innovative and Applied Bioprocessing, Mohali, India in 2015, as Scientist-C. He has been working in the area of molecular biology, and synthetic biology. In the area of plant molecular biology his some of the significant contribution are: development stringently regulated expression systems for inducing male sterility and male sterility-fertility restoration system in plants, investigation of tissue and cell-type specific distribution pattern of mineral nutrients in wheat grains and its possible impacts on bioavailability, the first transcriptome analysis and molecular insights into seed development biology in the fruit crops, Custard apple and Litchi, and secondary metabolite pathways in Rose-scented geranium, development of approaches based on Rootstock-scion or modified viral genome based long distance signalling as possible strategies for inducing trait modification such as seedlessness. His current research focus is towards development of synthetic biocatalysts for biotransformation of agro-industrial by-products and residues into value added biomolecules. In the area of biosynthetic technology his some of the significant contribution are: development of novel approaches for transformation of agro-industrial residues and bioresources into functional and prebiotic biomolecules, development of a novel strategy for the improvement of operational stability of D-psiose 3-epimerase enzyme. He has been interested in employing the basic knowledge for translational research. He has published 33 research papers in peer reviewed journals, 4 review articles/book chapters, and 4 patents to his credit. Prof. Ashok Pandey is currently Executive Director, Centre for Energy and Environmental Sustainability-India, Lucknow. His major research and technological development interests are industrial and environmental biotechnology and energy biosciences, focusing on biomass to biofuels and chemicals, waste to wealth and energy, etc.

Prof. Christian Larroche is Director of Polytech Clermont-Ferrand, a graduate school of engineering of University Clermont-Auvergne, France. He is also member of the research laboratory Institut Pascal and of the laboratory of excellence ImobS3 at the same university. He has strong research skills and expertise in the area of applied microbiology and biochemical engineering. He is author of 220 documents, including 114 articles, three patents, 15 book chapters and 24 co-editions of books or journal special issues. He is member of French Society for Process Engineering (SFGP), French Society of Biotechnology and European Federation of Chemical Engineering. He is administrator of IBA-IFIBiop and editor of Bioresource Technology. Professor Carlos Ricardo Soccol is the research group leader of DEBB (Department of Bioprocess Engineering and Biotechnology) at the Federal University of Paraná, Brazil, with twenty years of experience in biotechnological research and development of bioprocesses with industrial application. He is graduated in Chemical Engineering (UFPR, 1979), Master in Food Technology (UFPR, 1986) and Ph.D. in Genie Enzymatique, Microbiologie et Bioconversion (Université de Technologie de Compiègne,- France, 1992). Postdoctor at Institut ORSTOM/IRD (Montpellier, 1994 and 1997) and at the Université de Provence et de la Méditerranée (Marseille, 2000). He is HDR Professor at Ecole d'Ingénieurs Supériure of Luminy, Marseille-France. He has experience in the areas of Science and Food Technology, with emphasis on Agro-industrial and Agroalimentary Biotechnology, acting in the following areas: bioprocess engineering and solid state fermentation, submerged fermentation, bioseparations, industrial bioprocesses, enzyme technology, tissue culture, bio-industrial projects and bioproduction. He is currently Coordinator of Master BIODEV-UNESCO, Associate Editor of five international journals and Editor in Chief of Brazilian Archives of Biology and Technology Journal. Professor Soccol received several national and international awards which include Science & Technology award of the Govt. of Paraná (1996), Scopus/Elsevier award (2009), Dr. Honoris Causa, University Blaise Pascal-France (2010), Outstanding Scientist 5th International Conference on Industrial Bioprocesses, Taipei, Taiwan (2012), Elected Titular Member of the Brazilian Academy of Sciences (2014). He is a technical and scientific consultant of several companies, agencies and scientific journals in Brazil and abroad. He has supervised and formed 96 Master Science students, 48 PhD students and 14 Post-Doctorate Students. He has 995 publications/communications which include 17 books, 107 book chapters, 270 original research papers, 557 research communications in international and national conferences and has registered 44 patents. His research articles until the moment were cited (Scopus DataBase) 5600 Times with Index h=36.